Publications by authors named "Toshiya Oba"

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A cell-penetrating peptide derived from SARS-CoV-2 protein Orf9b allosterically inhibits MARK4 activity and mitigates tau toxicity.
Toshiya Oba, Daiki Homma, Sophia Jobien M Limlingan, Aoi Fukuchi, Akiko Asada

Neurobiol Dis· November 2023

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Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
Taro Saito, Tomoki Chiku, Mikiko Oka, Satoko Wada-Kakuda, Mika Nobuhara, Toshiya Oba

Hum Mol Genet· October 2021

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Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.
Toshiya Oba, Taro Saito, Akiko Asada, Sawako Shimizu, Koichi M Iijima

J Biol Chem· December 2020

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Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
Taro Saito, Toshiya Oba, Sawako Shimizu, Akiko Asada, Koichi M Iijima

Hum Mol Genet· September 2019

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