Publications by authors named "Tournier Nicolas"

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Premature aging and neuropathic behaviours induced by an acute low-dose exposure to a sarin surrogate.
Alexandre Champault, Sarah Leterrier, Rosalie Bel, Julie Knoertzer, Amélie Soyer, Nicolas Tournier

Toxicology· January 2026

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Imaging P-glycoprotein function at the blood-brain barrier in drug-resistant epilepsy using [C]metoclopramide.
Louise Breuil, Inès Arino, Myriam El Biali, Sebastian Rodrigo, Matthias Jackwerth, Nicolas Tournier

Eur J Nucl Med Mol Imaging· December 2025

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Comparing three methodologies for network analysis of human [C]glyburide whole-body PET data: d-networks, s-networks, and ΔPCC networks.
Abigail F Hellman, Paul S Clegg, Solène Marie, Nicolas Tournier, Adriana A S Tavares

EJNMMI Res· December 2025

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Modeling Whole-Body Dynamic PET Microdosing Data to Predict the Whole-Body Pharmacokinetics of Glyburide in Humans.
Léa Comin, Solène Marie, Moreno Ursino, Sarah Zohar, Nicolas Tournier

Clin Pharmacokinet· November 2025

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Quantitative monitoring of ketamine's impact on synaptic density using C-UCB-J PET imaging in the corticosterone mouse model of anxiety/depression.
Cassandre Corvo, Sébastien Goutal, Indira Mendez-David, Sarah Leterrier, Fabien Caille, Nicolas Tournier

Mol Psychiatry· November 2025

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Nanoparticle-Mediated Targeted Drug Delivery Systems.
Toshihiko Tashima, Nicolas Tournier

Pharmaceutics· November 2025

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Corrigendum to "Enhancing oxime efficacy into brain using ultrasound to counteract nerve agent exposure" [Biomed. Pharmacother. 187 (2025) 118120].
Lucie Lépinard, Sarah Leterrier, Laurène Jourdain, Louise Turri, Assia Belkebir, Nicolas Tournier

Biomed Pharmacother· July 2025

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Enhancing oxime efficacy into brain using ultrasound to counteract nerve agent exposure.
Lépinard Lucie, Leterrier Sarah, Jourdain Laurène, Turri Louise, Belkebir Assia, Tournier Nicolas

Biomed Pharmacother· June 2025

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Imaging the Activity of Efflux Transporters at the Blood-Brain Barrier in Neurologic Diseases: Radiotracer Selection Criteria.
Nicolas Tournier, Oliver Langer

J Nucl Med· May 2025

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Imaging the impact of sex and age on OATP function in humans: Consequences for whole-body pharmacokinetics and liver exposure.
Solène Marie, Anne-Lise Lecoq, Louise Breuil, Fabien Caillé, Vincent Lebon, Nicolas Tournier

Acta Pharm Sin B· May 2025

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PET Imaging of PD-L1 Occupancy for Preclinical Assessment of the Efficacy of Combined Anti-PD-L1 Immunotherapy and Targeted Therapy.
Céline Chevaleyre, Léa Zimmermann, Simon Specklin, Dimitri Kereselidze, Alizée Bouleau, Nicolas Tournier

J Nucl Med· April 2025

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TSPO-PET in pre-surgical evaluations: Correlation of neuroinflammation and SEEG epileptogenicity mapping in drug-resistant focal epilepsy.
Jennifer Kilmer, Sebatian Rodrigo, Ana-Maria Petrescu, Nozar Aghakhani, Anne Herbrecht, Nicolas Tournier

Epilepsia· February 2025

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Successful repositioning of mertansine for improved chemotherapy by combining a polymer prodrug approach and PET imaging.
Soizic Martin-Aubert, Kevin Avrillon, Nicolas Tournier, Alexandre Bordat, Vu Long Tran, Nicolas Tsapis, Julien Nicolas

J Control Release· February 2025

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Decreased opioid receptor availability and impaired neurometabolic coupling as signatures of morphine tolerance in male rats: A positron emission tomography study.
Amélie Soyer, Sarah Leterrier, Sébastien Goutal, Cassandre Corvo, Wadad Saba, Nicolas Tournier

Biomed Pharmacother· February 2025

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Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression.
Cassandre Corvo, Indira Mendez-David, Sébastien Goutal, Wadad Saba, Michel Bottlaender, Nicolas Tournier

ACS Pharmacol Transl Sci· February 2025

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Brain glucose metabolism as a neuronal substrate of the abnormal behavioral response to stress in the mdx mouse, a model of Duchenne muscular dystrophy.
Sébastien Goutal, Marion Lancien, François Rivier, Nicolas Tournier, Cyrille Vaillend

Neurobiol Dis· January 2025

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Impaired brain glucose metabolism as a biomarker for evaluation of dodecyl creatine ester in creatine transporter deficiency: Insights from patient brain-derived organoids and in vivo [18F]FDG PET imaging in a mouse model.
Clémence Disdier, Amélie Soyer, Léa Broca-Brisson, Sébastien Goutal, Anne-Cécile Guyot, Nicolas Tournier

Neurobiol Dis· November 2024

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[C]Metoclopramide PET can detect a seizure-induced up-regulation of cerebral P-glycoprotein in epilepsy patients.
Myriam El Biali, Louise Breuil, Matthias Jackwerth, Severin Mairinger, Maria Weber, Nicolas Tournier

Fluids Barriers CNS· October 2024

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[F]2-fluoro-2-deoxy-sorbitol ([F]FDS) PET imaging repurposed for quantitative estimation of blood-brain barrier permeability in a rat model of Alzheimer's disease.
Amélie Soyer, Sébastien Goutal, Sarah Leterrier, Solène Marie, Benoit Larrat, Nicolas Tournier

Ann Pharm Fr· September 2024

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Imaging quantitative changes in blood-brain barrier permeability using [F]2-fluoro-2-deoxy-sorbitol ([F]FDS) PET in relation to glial cell recruitment in a mouse model of endotoxemia.
Sarah Leterrier, Sébastien Goutal, Gaëlle Hugon, Maud Goislard, Wadad Saba, Nicolas Tournier

J Cereb Blood Flow Metab· July 2024

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Brain Glucose Metabolism as a Readout of the Central Nervous System Impact of Cigarette Smoke Exposure and Withdrawal and the Effects of NFL-101, as an Immune-Based Drug Candidate for Smoking Cessation Therapy.
Sébastien Goutal, Thi Tran, Claire Leroy, Nadine Benhamouda, Sarah Leterrier, Nicolas Tournier

ACS Chem Neurosci· July 2024

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St. John's wort extract with a high hyperforin content does not induce P-glycoprotein activity at the human blood-brain barrier.
Myriam El Biali, Michael Wölfl-Duchek, Matthias Jackwerth, Severin Mairinger, Maria Weber, Nicolas Tournier

Clin Transl Sci· May 2024

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Brain delivery enabled by transient blood-brain barrier disruption induced by regadenoson: a PET imaging study.
Benoit Hosten, Sébastien Goutal, Sarah Leterrier, Cassandre Corvo, Louise Breuil, Nicolas Tournier

Expert Opin Drug Deliv· May 2024

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Non-Invasive Device-Mediated Drug Delivery to the Brain across the Blood-Brain Barrier.
Toshihiko Tashima, Nicolas Tournier

Pharmaceutics· March 2024

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Performance and Sensitivity of [Tc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver.
Irene Hernández-Lozano, Sarah Leterrier, Severin Mairinger, Johann Stanek, Anna S Zacher, Nicolas Tournier

Mol Pharm· February 2024

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