Publications by authors named "Trisha Brock"

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Dynamicasome-a molecular dynamics-guided and AI-driven pathogenicity prediction catalogue for all genetic mutations.
Naeyma N Islam, Mathew A Coban, Jessica M Fuller, Caleb Weber, Rohit Chitale, Trisha J Brock

Commun Biol· July 2025

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Environmental carcinogen benzo[a]pyrene alters neutral lipid storage via a cyp-35A2 mediated pathway in Caenorhabditis elegans.
Yuzhi Chen, Mustafa Abbass, Trisha Brock, Gian Hobbs, Leonardo A Ciufo

Environ Pollut· December 2023

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A humanized Caenorhabditis elegans model of hereditary spastic paraplegia-associated variants in KLC4.
Selin Gümüşderelioğlu, Lauren Resch, Trisha Brock, , G W Gant Luxton

Dis Model Mech· August 2023

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Caenorhabditis elegans models for striated muscle disorders caused by missense variants of human LMNA.
Ellen F Gregory, Shilpi Kalra, Trisha Brock, Gisèle Bonne, G W Gant Luxton

PLoS Genet· August 2023

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Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics.
Christopher E Hopkins, Trisha Brock, Thomas R Caulfield, Matthew Bainbridge

Mol Aspects Med· June 2023

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Clinical variants in expressing human STXBP1 reveal a novel class of pathogenic variants and classify variants of uncertain significance.
Christopher E Hopkins, Kathryn McCormick, Trisha Brock, Matthew Wood, Sarah Ruggiero

Genet Med Open· June 2023

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Generation of a null allele and humanized containing human disease-variants.
Jeremy Lins, Trisha J Brock, Chris E Hopkins, Anne C Hart

MicroPubl Biol· June 2023

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A humanized model of Hereditary Spastic Paraplegia-associated variants in kinesin light chain KLC4.
Selin Gümüşderelioğlu, Lauren Resch, Trisha Brock, , G W Gant Luxton

bioRxiv· January 2023

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The use of CRISPR to generate a whole-gene humanized and the examination of P301L and G272V clinical variants, along with the creation of deletion null alleles of and loci.
Jeremy Lins, Christopher E Hopkins, Trisha Brock, Anne C Hart

MicroPubl Biol· September 2022

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Atropine reduces aldicarb-induced sensitivity to electroshock model.
Nirthieca Suthakaran, Trisha Brock, Akshay Naraine, Paola Gonzalez-Lerma, Chris Hopkins

MicroPubl Biol· August 2022

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Neuronal control of maternal provisioning in response to social cues.
Jadiel A Wasson, Gareth Harris, Sabine Keppler-Ross, Trisha J Brock, Abdul R Dar

Sci Adv· August 2021

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Precision deletion of the entire coding sequence of the locus causes increase in pharyngeal pumping frequency.
Trisha Brock, Stelian Pop, Chandler Bradford, Jenn Lawson, Lauren Resch

MicroPubl Biol· June 2017

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A Caenorhabditis elegans model for ether lipid biosynthesis and function.
Xun Shi, Pablo Tarazona, Trisha J Brock, John Browse, Ivo Feussner

J Lipid Res· February 2016

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Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response.
Mei Zhong, Wei Niu, Zhi John Lu, Mihail Sarov, John I Murray, Trisha Brock

PLoS Genet· February 2010

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Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans.
Trisha J Brock, John Browse, Jennifer L Watts

Genetics· June 2007

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Genetic regulation of unsaturated fatty acid composition in C. elegans.
Trisha J Brock, John Browse, Jennifer L Watts

PLoS Genet· July 2006

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