Publications by authors named "Tristan Felix"

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Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease.
Letizia Fontana, Pierre Martinucci, Simone Amistadi, Tristan Felix, Margaux Mombled

Cell Rep Med· October 2025

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Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies.
Simone Amistadi, Letizia Fontana, Chiara Magnoni, Tristan Felix, Matteo Kane Charvin

Nucleic Acids Res· July 2025

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Severe inflammation and lineage skewing are associated with poor engraftment of engineered hematopoietic stem cells in patients with sickle cell disease.
Steicy Sobrino, Laure Joseph, Elisa Magrin, Anne Chalumeau, Nicolas Hebert, Tristan Felix

Nat Commun· April 2025

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Safety and efficacy studies of CRISPR-Cas9 treatment of sickle cell disease highlights disease-specific responses.
Giacomo Frati, Megane Brusson, Gilles Sartre, Bochra Mlayah, Tristan Felix

Mol Ther· December 2024

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Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells.
Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix

Nat Commun· June 2024

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Novel lentiviral vectors for gene therapy of sickle cell disease combining gene addition and gene silencing strategies.
Mégane Brusson, Anne Chalumeau, Pierre Martinucci, Oriana Romano, Tristan Felix

Mol Ther Nucleic Acids· June 2023

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Adenine base editor-mediated correction of the common and severe IVS1-110 (G>A) β-thalassemia mutation.
Giulia Hardouin, Panagiotis Antoniou, Pierre Martinucci, Tristan Felix, Sandra Manceau

Blood· March 2023

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Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.
Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Giacomo Frati, Tristan Felix

Nat Commun· November 2022

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Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease.
Sophie Ramadier, Anne Chalumeau, Tristan Felix, Nadia Othman, Sherazade Aknoun

Mol Ther· January 2022

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GATA Factor-Mediated Gene Regulation in Human Erythropoiesis.
Oriana Romano, Luca Petiti, Tristan Felix, Vasco Meneghini, Michel Portafax

iScience· April 2020

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Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Leslie Weber, Giacomo Frati, Tristan Felix, Giulia Hardouin, Antonio Casini

Sci Adv· February 2020

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Optimization of CRISPR/Cas9 Delivery to Human Hematopoietic Stem and Progenitor Cells for Therapeutic Genomic Rearrangements.
Annalisa Lattanzi, Vasco Meneghini, Giulia Pavani, Fatima Amor, Sophie Ramadier, Tristan Felix

Mol Ther· January 2019

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Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8 T Cell Responses.
Céline Cousin, Marine Oberkampf, Tristan Felix, Pierre Rosenbaum, Robert Weil

Cell Rep· January 2019

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An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype.
Leslie Weber, Valentina Poletti, Elisa Magrin, Chiara Antoniani, Samia Martin, Tristan Felix

Mol Ther Methods Clin Dev· September 2018

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Plerixafor enables safe, rapid, efficient mobilization of hematopoietic stem cells in sickle cell disease patients after exchange transfusion.
Chantal Lagresle-Peyrou, François Lefrère, Elisa Magrin, Jean-Antoine Ribeil, Oriana Romano

Haematologica· May 2018

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Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus.
Chiara Antoniani, Vasco Meneghini, Annalisa Lattanzi, Tristan Felix, Oriana Romano

Blood· April 2018

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Human mutations affect the epigenetic/bookmarking function of HNF1B.
Jonathan Lerner, Alessia Bagattin, Francisco Verdeguer, Munevver P Makinistoglu, Serge Garbay, Tristan Felix

Nucleic Acids Res· September 2016

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Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach.
Maria H Daleke-Schermerhorn, Tristan Felix, Zora Soprova, Corinne M Ten Hagen-Jongman, David Vikström

Appl Environ Microbiol· September 2014

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Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses.
Gilles Dadaglio, Catherine Fayolle, Xiaoming Zhang, Bernard Ryffel, Marine Oberkampf, Tristan Felix

J Immunol· August 2014

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A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malaria.
Frédéric Coutant, Raul Yusef Sanchez David, Tristan Félix, Aude Boulay, Laxmee Caleechurn

PLoS One· May 2013

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Expression of miR-124 inhibits growth of medulloblastoma cells.
Joachim Silber, Rintaro Hashizume, Tristan Felix, Sujatmi Hariono, Mamie Yu

Neuro Oncol· January 2013

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