Publications by authors named "Troy A McEachron"

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STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma.
Elizabeth P Young, Christine A Johnson, Alex G Lee, Douglass Morris, Jessica Tsui, Troy A McEachron

bioRxiv· October 2025

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Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases.
Jason Eigenbrood, Nathan Wong, Paul Mallory, Janice S Pereira, Demond Williams, Troy A McEachron

Cancer Res· June 2025

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Spatial profiling identifies regionally distinct microenvironments and targetable immunosuppressive mechanisms in pediatric osteosarcoma pulmonary metastases.
Jason Eigenbrood, Nathan Wong, Paul Mallory, Janice Pereira, Douglass W Morris-Ii, Troy A McEachron

bioRxiv· January 2025

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Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans.
Joshua D Mannheimer, Gregory Tawa, David Gerhold, John Braisted, Carly M Sayers, Troy A McEachron

Commun Biol· August 2023

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Highly Multiplexed Spatially Resolved Proteomic and Transcriptional Profiling of the Glioblastoma Microenvironment Using Archived Formalin-Fixed Paraffin-Embedded Specimens.
Youngmi Kim, Patrick Danaher, Patrick J Cimino, Kyle Hurth, Sarah Warren, Troy A McEachron

Mod Pathol· January 2023

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Immunohistochemical analysis of glassy cell carcinoma of the cervix reveals robust lymphocyte infiltrate and the expression of targetable inhibitory immune checkpoints.
Erin A Blake, Malcolm S Ross, Megan E Ross, Koji Matsuo, Emily T Silverstein, Troy A McEachron

Arch Gynecol Obstet· February 2022

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Recent Advances in Pediatric Cancer Research.
Troy A McEachron, Lee J Helman

Cancer Res· December 2021

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Applicability of spatial transcriptional profiling to cancer research.
Rania Bassiouni, Lee D Gibbs, David W Craig, John D Carpten, Troy A McEachron

Mol Cell· April 2021

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Targeted transcriptional profiling of the tumor microenvironment reveals lymphocyte exclusion and vascular dysfunction in metastatic osteosarcoma.
Laurie Sorenson, Yanfen Fu, Tressa Hood, Sarah Warren, Troy A McEachron

Oncoimmunology· February 2021

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Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group.
Pooja Hingorani, Valentin Dinu, Xiyuan Zhang, Haiyan Lei, Jack F Shern, Troy A McEachron

Sci Rep· July 2020

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Profiling targetable immune checkpoints in osteosarcoma.
Troy A McEachron, Timothy J Triche, Laurie Sorenson, David M Parham, John D Carpten

Oncoimmunology· September 2018

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Molecular Genetic Profiling of Adolescent Glassy Cell Carcinoma of the Cervix Reveals Targetable EGFR Amplification with Potential Therapeutic Implications.
Troy A McEachron, Leonard S Sender, Keri B Zabokrtsky, Brian Kaltenecker, W Nathan Holmes

J Adolesc Young Adult Oncol· September 2016

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Successful Treatment of Genetically Profiled Pediatric Extranodal NK/T-Cell Lymphoma Targeting Oncogenic STAT3 Mutation.
Troy A McEachron, Ivan Kirov, Minkkwan Wungwattana, Daisy Cortes, Keri B Zabokrtsky

Pediatr Blood Cancer· April 2016

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Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4.
Pilar Ramos, Anthony N Karnezis, David W Craig, Aleksandar Sekulic, Megan L Russell, Troy A McEachron

Nat Genet· May 2014

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Histone H3 mutations in pediatric brain tumors.
Xiaoyang Liu, Troy A McEachron, Jeremy Schwartzentruber, Gang Wu

Cold Spring Harb Perspect Biol· April 2014

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An integrated approach to identifying clinically relevant targets in pediatric gliomas.
Troy A McEachron, Patrick Tomboc, Nhan L Tran

CNS Oncol· July 2013

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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
Gang Wu, Alberto Broniscer, Troy A McEachron, Charles Lu, Barbara S Paugh

Nat Genet· January 2012

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Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells.
Troy A McEachron, Frank C Church, Nigel Mackman

Blood Coagul Fibrinolysis· October 2011

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Protease-activated receptors mediate crosstalk between coagulation and fibrinolysis.
Troy A McEachron, Rafal Pawlinski, Kristy L Richards, Frank C Church, Nigel Mackman

Blood· December 2010

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