Publications by authors named "Troy Barger"

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Inhibition of RANKL is critical for accurate assessment of anti-drug antibody incidence to denosumab in clinical studies.
Mieke Jill Miller, Mark A Kroenke, Troy Barger, Marta Starcevic Manning, Winnie Sohn

J Immunol Methods· May 2025

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Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target.
Mark A Kroenke, Troy E Barger, Jenny Hu, Mieke Jill Miller, Kevin Kalenian

Front Immunol· February 2022

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Assessment of romiplostim immunogenicity in pediatric patients in clinical trials and in a global postmarketing registry.
Charles Bowers, Daniel T Mytych, Tatiana Lawrence, Kejia Wang, Troy E Barger

Blood Adv· December 2021

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Anti-drug Antibody Validation Testing and Reporting Harmonization.
Heather Myler, João Pedras-Vasconcelos, Kelli Phillips, Charles Scott Hottenstein, Paul Chamberlain, Troy Barger

AAPS J· December 2021

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Assessment of romiplostim immunogenicity in adult patients in clinical trials and in a global postmarketing registry.
Daniel T Mytych, Joseph K Park, June Kim, Troy E Barger, Andy Boshier

Br J Haematol· September 2020

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Establishment of the first WHO Erythropoietin antibody reference panel: Report of an international collaborative study.
Meenu Wadhwa, Daniel T Mytych, Chris Bird, Troy Barger, Thomas Dougall

J Immunol Methods· August 2016

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2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3--LBA, biomarkers and immunogenicity).
Lakshmi Amaravadi, An Song, Heather Myler, Theingi Thway, Susan Kirshner, Troy Barger

Bioanalysis· December 2015

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Comparison of cell-based and non-cell-based assay platforms for the detection of clinically relevant anti-drug neutralizing antibodies for immunogenicity assessment of therapeutic proteins.
Jenny Hu, Iwona Wala, Hong Han, Janice Nagatani, Troy Barger

J Immunol Methods· April 2015

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Dose-related differences in the pharmacodynamic and toxicologic response to a novel hyperglycosylated analog of recombinant human erythropoietin in Sprague-Dawley rats with similarly high hematocrit.
Dina A Andrews, Babette M Boren, James R Turk, Rogely W Boyce, Yudong D He, Troy E Barger

Toxicol Pathol· December 2014

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Cytokines associated with increased erythropoiesis in Sprague-Dawley rats administered a novel hyperglycosylated analog of recombinant human erythropoietin.
Dina A Andrews, Hisham K Hamadeh, Yudong D He, Babette M Boren, James R Turk, Troy E Barger

Toxicol Pathol· December 2014

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A detailed examination of the antibody prevalence and characteristics of anti-ESA antibodies.
Troy E Barger, Deborah Wrona, Theresa J Goletz, Daniel T Mytych

Nephrol Dial Transplant· October 2012

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Development and characterization of a human antibody reference panel against erythropoietin suitable for the standardization of ESA immunogenicity testing.
Daniel T Mytych, Troy E Barger, Chadwick King, Stephanie Grauer, Raj Haldankar

J Immunol Methods· August 2012

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Detection of anti-ESA antibodies in human samples from PRCA and non-PRCA patients: an immunoassay platform comparison.
Troy E Barger, Andrew J Kuck, Narendra Chirmule, Steven J Swanson, Daniel T Mytych

Nephrol Dial Transplant· February 2012

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Strategy to confirm the presence of anti-erythropoietin neutralizing antibodies in human serum.
Sergio Sanchez, Troy Barger, Lei Zhou, Michael Hale, Daniel Mytych

J Pharm Biomed Anal· July 2011

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Comparing exponentially weighted moving average and run rules in process control of semiquantitative immunogenicity immunoassays.
Troy E Barger, Lei Zhou, Michael Hale, Michael Moxness, Steven J Swanson

AAPS J· March 2010

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The development and validation of a sensitive, dual-flow cell, SPR-based biosensor immunoassay for the detection, semi-quantitation, and characterization of antibodies to darbepoetin alfa and epoetin alfa in human serum.
Daniel T Mytych, Stephon La, Troy Barger, John Ferbas, Steven J Swanson

J Pharm Biomed Anal· February 2009

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