Publications by authors named "Troy Cellmer"

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Therapeutic potential of the latest oxygen affinity-modifying agent, GBT021601, for treating sickle cell disease is questionable.
Braydon Alaimo, Belhu Metaferia, Troy Cellmer, Swee Lay Thein, H Franklin Bunn

Br J Haematol· December 2024

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Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease.
Angelo D'Alessandro, Kang Le, Maureen Lundt, Quan Li, Emily B Dunkelberger, Troy Cellmer

Haematologica· August 2024

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In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation.
Alexis K Leonard, Dana Furstenau, Zaina Inam, Christina Luckett, Rebecca Chu, Troy Cellmer

Blood Adv· April 2024

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Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
Belhu Metaferia, Troy Cellmer, Emily B Dunkelberger, Quan Li, Eric R Henry

Proc Natl Acad Sci U S A· October 2022

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Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
Eric R Henry, Belhu Metaferia, Quan Li, Julia Harper, Robert B Best, Troy Cellmer

Blood· September 2021

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Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Eric R Henry, Troy Cellmer, Emily B Dunkelberger, Belhu Metaferia, James Hofrichter

Proc Natl Acad Sci U S A· June 2020

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Theoretical Simulation of Red Cell Sickling Upon Deoxygenation Based on the Physical Chemistry of Sickle Hemoglobin Fiber Formation.
Emily B Dunkelberger, Belhu Metaferia, Troy Cellmer, Eric R Henry

J Phys Chem B· December 2018

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Dynamics of Structural Elements of GB1 β-Hairpin Revealed by Tryptophan-Cysteine Contact Formation Experiments.
Andrea Soranno, Francesca Cabassi, Maria Elena Orselli, Troy Cellmer, Alessandro Gori

J Phys Chem B· December 2018

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Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
Quan Li, Eric R Henry, James Hofrichter, Jeffrey F Smith, Troy Cellmer

Proc Natl Acad Sci U S A· January 2017

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Universality of supersaturation in protein-fiber formation.
Troy Cellmer, Frank A Ferrone, William A Eaton

Nat Struct Mol Biol· May 2016

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Measuring ultrafast protein folding rates from photon-by-photon analysis of single molecule fluorescence trajectories.
Hoi Sung Chung, Troy Cellmer, John M Louis, William A Eaton

Chem Phys· August 2013

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Coarse-grained simulations of protein aggregation.
Troy Cellmer, Nicolas L Fawzi

Methods Mol Biol· December 2012

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Evidence of multiple folding pathways for the villin headpiece subdomain.
Li Zhu, Kingshuk Ghosh, Michael King, Troy Cellmer, Olgica Bakajin

J Phys Chem B· November 2011

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Extracting rate coefficients from single-molecule photon trajectories and FRET efficiency histograms for a fast-folding protein.
Hoi Sung Chung, Irina V Gopich, Kevin McHale, Troy Cellmer, John M Louis

J Phys Chem A· April 2011

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Making connections between ultrafast protein folding kinetics and molecular dynamics simulations.
Troy Cellmer, Marco Buscaglia, Eric R Henry, James Hofrichter, William A Eaton

Proc Natl Acad Sci U S A· April 2011

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Chemical, physical, and theoretical kinetics of an ultrafast folding protein.
Jan Kubelka, Eric R Henry, Troy Cellmer, James Hofrichter, William A Eaton

Proc Natl Acad Sci U S A· December 2008

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Measuring internal friction of an ultrafast-folding protein.
Troy Cellmer, Eric R Henry, James Hofrichter, William A Eaton

Proc Natl Acad Sci U S A· November 2008

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Relaxation rate for an ultrafast folding protein is independent of chemical denaturant concentration.
Troy Cellmer, Eric R Henry, Jan Kubelka, James Hofrichter, William A Eaton

J Am Chem Soc· November 2007

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Protein aggregation in silico.
Troy Cellmer, Dusan Bratko, John M Prausnitz, Harvey W Blanch

Trends Biotechnol· June 2007

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Kinetic studies of protein L aggregation and disaggregation.
Troy Cellmer, Rutger Douma, Ansgar Huebner, John Prausnitz, Harvey Blanch

Biophys Chem· February 2007

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Molecular simulation of protein aggregation.
Dusan Bratko, Troy Cellmer, John M Prausnitz, Harvey W Blanch

Biotechnol Bioeng· January 2007

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Effect of single-point sequence alterations on the aggregation propensity of a model protein.
Dusan Bratko, Troy Cellmer, John M Prausnitz, Harvey W Blanch

J Am Chem Soc· February 2006

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Protein-folding landscapes in multichain systems.
Troy Cellmer, Dusan Bratko, John M Prausnitz, Harvey Blanch

Proc Natl Acad Sci U S A· August 2005

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Interactions of lysozyme in guanidinium chloride solutions from static and dynamic light-scattering measurements.
Wei Liu, Troy Cellmer, David Keerl, John M Prausnitz, Harvey W Blanch

Biotechnol Bioeng· May 2005

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Thermodynamics of folding and association of lattice-model proteins.
Troy Cellmer, Dusan Bratko, John M Prausnitz, Harvey Blanch

J Chem Phys· May 2005

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