Publications by authors named "Troy Harkness"

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Activation of the Anaphase Promoting Complex Restores Impaired Mitotic Progression and Chemosensitivity in Multiple Drug-Resistant Human Breast Cancer.
Mathew Lubachowski, Cordell VanGenderen, Sarah Valentine, Zach Belak, Gerald Floyd Davies, Troy Anthony Alan Harkness

Cancers (Basel)· April 2024

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Activation of the Anaphase Promoting Complex Reverses Multiple Drug Resistant Cancer in a Canine Model of Multiple Drug Resistant Lymphoma.
Terra G Arnason, Valerie MacDonald-Dickinson, Matthew Casey Gaunt, Gerald F Davies, Liubov Lobanova, Troy A A Harkness

Cancers (Basel)· August 2022

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Smc5/6 in the rDNA modulates lifespan independently of Fob1​.
Sarah Moradi-Fard, Aditya Mojumdar, Megan Chan, Troy A A Harkness, Jennifer A Cobb

Aging Cell· June 2021

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High-Throughput Rapid Yeast Chronological Lifespan Assay.
Abd-Al-Wahab Khawaja, Zach R Belak, Christopher H Eskiw, Troy A A Harkness

Methods Mol Biol· March 2021

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The role of Anaphase Promoting Complex activation, inhibition and substrates in cancer development and progression.
Cordell VanGenderen, Troy Anthony Alan Harkness, Terra Gayle Arnason

Aging (Albany NY)· August 2020

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The Nuclear Lamina: Protein Accumulation and Disease.
Carla Almendáriz-Palacios, Zoe E Gillespie, Matthew Janzen, Valeria Martinez, Joanna M Bridger, Troy A A Harkness

Biomedicines· July 2020

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A rapid, high-throughput method for determining chronological lifespan in budding yeast.
Zachery R Belak, Troy Harkness, Christopher H Eskiw

J Biol Methods· December 2018

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Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan.
Zheng Hu, Bo Xia, Spike Dl Postnikoff, Zih-Jie Shen, Alin S Tomoiaga, Troy A Harkness

Elife· August 2018

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Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan.
Troy A A Harkness

Int J Mol Sci· June 2018

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Rapid Nuclear Exclusion of Hcm1 in Aging Leads to Vacuolar Alkalization and Replicative Senescence.
Ata Ghavidel, Kunal Baxi, Martin Prusinkiewicz, Cynthia Swan, Zach R Belak, Troy A Harkness

G3 (Bethesda)· May 2018

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Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer.
Gerald Davies, Liubov Lobanova, Wojciech Dawicki, Gary Groot, John R Gordon, Troy Harkness

PLoS One· January 2018

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Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in .
Kunal Baxi, Ata Ghavidel, Brandon Waddell, Troy A Harkness, Carlos E de Carvalho

Genetics· September 2017

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Novel Dimer Compounds That Bind α-Synuclein Can Rescue Cell Growth in a Yeast Model Overexpressing α-Synuclein. A Possible Prevention Strategy for Parkinson's Disease.
Joe Kakish, Kevin J H Allen, Troy A Harkness, Ed S Krol, Jeremy S Lee

ACS Chem Neurosci· December 2016

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The ubiquitin-conjugating enzyme, Ubc1, indirectly regulates SNF1 kinase activity via Forkhead-dependent transcription.
Rubin Jiao, Liubov Lobanova, Amanda Waldner, Anthony Fu, Linda Xiao, Troy A Harkness

Microb Cell· November 2016

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A short motif in Arabidopsis CDK inhibitor ICK1 decreases the protein level, probably through a ubiquitin-independent mechanism.
Qin Li, Xianzong Shi, Shengjian Ye, Sheng Wang, Ron Chan, Troy Harkness

Plant J· September 2016

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Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance.
Mackenzie E Malo, Spike D L Postnikoff, Terra G Arnason, Troy A A Harkness

Aging (Albany NY)· April 2016

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Living longer through mitochondrial housekeeping.
Troy A A Harkness

Cell Cycle· March 2016

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Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1.
Terra Arnason, Troy Harkness

Cancers (Basel)· October 2015

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A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.
Ata Ghavidel, Kunal Baxi, Vladimir Ignatchenko, Martin Prusinkiewicz, Terra G Arnason, Troy A A Harkness

PLoS Genet· August 2015

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The SNF1 Kinase Ubiquitin-associated Domain Restrains Its Activation, Activity, and the Yeast Life Span.
Rubin Jiao, Spike Postnikoff, Troy A Harkness, Terra G Arnason

J Biol Chem· June 2015

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TFPI1 mediates resistance to doxorubicin in breast cancer cells by inducing a hypoxic-like response.
Gerald F Davies, Arnie Berg, Spike D L Postnikoff, Heather L Wilson, Terra G Arnason, Troy A A Harkness

PLoS One· December 2014

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Replicative and chronological life-span assays.
Spike D L Postnikoff, Troy A A Harkness

Methods Mol Biol· December 2014

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The anaphase promoting complex regulates yeast lifespan and rDNA stability by targeting Fob1 for degradation.
Johannes Menzel, Mackenzie E Malo, Cynthia Chan, Martin Prusinkiewicz, Terra G Arnason, Troy A A Harkness

Genetics· March 2014

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The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.
Vladimir I Titorenko, Troy A A Harkness

Front Physiol· November 2012

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The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex.
Spike D L Postnikoff, Mackenzie E Malo, Berchman Wong, Troy A A Harkness

PLoS Genet· September 2012

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