Publications by authors named "Troy Messick"

Claim this Profile
B
Bioassay-guided Isolation of SARS-CoV-2 Viral Entry Inhibitors From the Brown Algae Lobophora variegata Identifies Fucoxanthin as a Selective ACE-2/Spike Inhibitor.
Victoria M Casimir-Montán, Marie L Matos-Hernández, Adrián González-Bravo, Edwin A Hernández-Delgado, Grayce Dyer, Troy E Messick

Chem Biodivers· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural Basis for TRF2-RAP1 Recruitment by EBNA1 at the EBV origin of replication.
Paul Lieberman, Samantha Sustek, Troy Messick, Jayaraju Dheekollu, Coltin Albitz

Res Sq· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
First-in-Human Clinical Trial of a Small-Molecule EBNA1 Inhibitor, VK-2019, in Patients with Epstein-Barr-Positive Nasopharyngeal Cancer, with Pharmacokinetic and Pharmacodynamic Studies.
A Dimitrios Colevas, Zahra Talebi, Elizabeth Winters, Caroline Even, Victor Ho-Fun Lee, Troy E Messick

Clin Cancer Res· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of novel and highly selective SARS-CoV-2 main protease inhibitors.
Adi N R Poli, Ian Tietjen, Nitesh K Nandwana, Joel Cassel, Troy E Messick

Antimicrob Agents Chemother· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.
Marie L Matos-Hernández, Robert Samples, Grayce Dyer, Victoria M Casimir Montán, Chris A Morales-Colón, Troy E Messick

J Nat Prod· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Validation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of VK-2019, a selective EBNA1 inhibitor.
Michael T Davis, Nicole M Anders, A Dimitrios Colevas, Troy E Messick, Michelle A Rudek

Biomed Chromatogr· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
EBNA1 Inhibitors Block Proliferation of Spontaneous Lymphoblastoid Cell Lines From Patients With Multiple Sclerosis and Healthy Controls.
Maria Chiara G Monaco, Samantha S Soldan, Chenhe Su, Annaliese Clauze, John F Cooper, Troy E Messick

Neurol Neuroimmunol Neuroinflamm· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Therapeutic approaches to Epstein-Barr virus cancers.
Samantha S Soldan, Troy E Messick, Paul M Lieberman

Curr Opin Virol· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cryo-EM Structure and Functional Studies of EBNA1 Binding to the Family of Repeats and Dyad Symmetry Elements of Epstein-Barr Virus .
Yang Mei, Troy E Messick, Jayaraju Dheekollu, Hee Jong Kim, Sudheer Molugu

J Virol· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Natural Stilbenoid (-)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants.
Ian Tietjen, Joel Cassel, Emery T Register, Xiang Yang Zhou, Troy E Messick

Antimicrob Agents Chemother· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein-Barr virus-associated gastric cancer.
Samantha S Soldan, Emma M Anderson, Drew M Frase, Yue Zhang, Lisa B Caruso, Troy E Messick

Gastric Cancer· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes.
Samantha S Soldan, Chenhe Su, R Jason Lamontagne, Nicholas Grams, Fang Lu, Troy E Messick

PLoS Pathog· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cell-cycle-dependent EBNA1-DNA crosslinking promotes replication termination at oriP and viral episome maintenance.
Jayaraju Dheekollu, Andreas Wiedmer, Kasirajan Ayyanathan, Julianna S Deakyne, Troy E Messick

Cell· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Troy E Messick, Lois Tolvinski, Edward R Zartler, Anna Moberg, Åsa Frostell

Molecules· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
Kimberly A Malecka, Jayaraju Dheekollu, Julianna S Deakyne, Andreas Wiedmer, Ursula D Ramirez, Troy E Messick

J Virol· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Jayaraju Dheekollu, Kimberly Malecka, Andreas Wiedmer, Henri-Jacques Delecluse, Alan K S Chiang, Troy E Messick

Oncotarget· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Troy E Messick, Garry R Smith, Samantha S Soldan, Mark E McDonnell, Julianna S Deakyne

Sci Transl Med· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.
Julianna S Deakyne, Kimberly A Malecka, Troy E Messick, Paul M Lieberman

J Virol· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Jayaraju Dheekollu, Kimberly Malecka, Andreas Wiedmer, Henri-Jacques Delecluse, Alan K S Chiang, Troy E Messick

Oncotarget· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus.
Jayaraju Dheekollu, Andreas Wiedmer, Daniel Sentana-Lledo, Joel Cassel, Troy Messick

J Virol· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling.
Benjamin Y Owusu, Namita Bansal, Phanindra K M Venukadasula, Larry J Ross, Troy E Messick

Oncotarget· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Computational analysis of EBNA1 "druggability" suggests novel insights for Epstein-Barr virus inhibitor design.
Eleonora Gianti, Troy E Messick, Paul M Lieberman, Randy J Zauhar

J Comput Aided Mol Des· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation.
Phanindra K M Venukadasula, Benjamin Y Owusu, Namita Bansal, Larry J Ross, Judith V Hobrath, Troy E Messick

ACS Med Chem Lett· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme.
Kevin Tsai, Troy E Messick, Paul M Lieberman

Curr Opin Virol· October 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer.
Susan M Domchek, Jiangbo Tang, Jill Stopfer, Dana R Lilli, Nancy Hamel, Troy E Messick

Cancer Discov· April 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis