Publications by authors named "TsuHan Lin"

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Pharmacokinetics and safety of sacubitril/valsartan (LCZ696) in patients with mild and moderate hepatic impairment
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Kenneth M Kulmatycki, Thomas Langenickel, Wai Hong Ng, Parasar Pal, Wei Zhou, Tsu-Han Lin

Int J Clin Pharmacol Ther· September 2017

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Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.
Wen Lin, Tao Ji, Heidi Einolf, Surya Ayalasomayajula, Tsu-Han Lin

J Pharm Sci· May 2017

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Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats.
Li Li, Kapil Vashisht, Julie Boisclair, Wenkui Li, Tsu-Han Lin

Toxicol Appl Pharmacol· August 2015

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Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor.
Sachiko Mita, Dan Meyers, Parasar Pal, TsuHan Lin, Tapan Majumdar

Clin Pharmacokinet· July 2015

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Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor.
Masaru Hirano, Dan Meyers, GangaRaju Golla, Parasar Pal, Pascale Pinot, TsuHan Lin

Clin Pharmacokinet· July 2015

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Application of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect.
Hefei Zhang, Binfeng Xia, Jennifer Sheng, Tycho Heimbach, Tsu-Han Lin

AAPS PharmSciTech· April 2014

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Utility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound.
Binfeng Xia, Tycho Heimbach, Tsu-han Lin, Shoufeng Li, Hefei Zhang

AAPS PharmSciTech· September 2013

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Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.
Tycho Heimbach, Binfeng Xia, Tsu-han Lin, Handan He

AAPS J· January 2013

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Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability.
Binfeng Xia, Tycho Heimbach, Handan He, Tsu-han Lin

Biopharm Drug Dispos· December 2012

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Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions.
Binfeng Xia, Tycho Heimbach, Tsu-han Lin, Handan He, Yanfeng Wang

Cancer Chemother Pharmacol· June 2012

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Unsymmetrical squaraines incorporating the thiophene unit for panchromatic dye-sensitized solar cells.
Jheng-Ying Li, Chia-Yuan Chen, Chuan-Pei Lee, Szu-Chien Chen, Tsu-Han Lin

Org Lett· December 2010

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Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).
Jessie Gu, Adele Noe, Priya Chandra, Suliman Al-Fayoumi, Monica Ligueros-Saylan, Tsu-Han Lin

J Clin Pharmacol· April 2010

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Effects of hepatic impairment on the pharmacokinetics of nilotinib: an open-label, single-dose, parallel-group study.
Ophelia Q P Yin, Neil Gallagher, Chiaki Tanaka, Deirdre Fisher, Venkat Sethuraman, Tsu-Han Lin

Clin Ther· February 2010

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9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
Clinton J Grubbs, Donald L Hill, Kirby I Bland, Samuel W Beenken, Tsu-Han Lin

Cancer Lett· November 2003

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