Publications by authors named "Tsung Lin"

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Effectiveness of abdominal sandbag training in enhancing diaphragm muscle function and exercise tolerance in patients with chronic respiratory failure.
Tsung Ko Lin, Miao Yu Chen, Hsin Han Cheng, Julie Chow, Chin Ming Chen

J Formos Med Assoc· October 2024

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A pilot pharmacokinetic and Metabolite identification study of Erinacine A in a Single landrace pig model.
Ying-Yu Chen, Ting-Wei Lin, I-Chen Li, Lin Tsung, Chun-Hsiang Hou

Heliyon· September 2024

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Cardiac-targeted delivery of a novel Drp1 inhibitor for acute cardioprotection.
Jarmon G Lees, David W Greening, David A Rudd, Jonathon Cross, Ayeshah A Rosdah, Tsung Wu Lin

J Mol Cell Cardiol Plus· September 2024

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Mitigate cross-market competition caused by the risk of uncertainty and improve firm performance through business intelligence.
Xueliang Han, Tsung Xian Lin, Xiao Wang

Heliyon· July 2024

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The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans.
Jonathan N Bauman, Angela C Doran, Amanda King-Ahmad, Raman Sharma, Gregory S Walker, Jian Lin, Tsung H Lin

Drug Metab Dispos· August 2022

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Preoperative Urine Analysis is An Effective Tool to Predict Fever After Miniaturized Percutaneous Nephrolithotomy on Large Renal Stones.
Ze-Hong Lu, Tsung Yen Lin, Ho Shiang Huang, Chan Jung Liu

Urol J· September 2021

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A Retrospective Study of Unicompartmental Knee Arthroplasty Functional Outcome and the Incidence of Medial Meniscus Posterior Root Tear in Spontaneous Osteonecrosis of the Knee.
Po-Ju Wu, Tsung Yu Lin, Yung Chang Lu

Biomed Res Int· May 2021

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Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases.
Brian S Gerstenberger, Catherine Ambler, Eric P Arnold, Mary-Ellen Banker, Matthew F Brown, Brett D Hollingshead, David W Lin, Tsung H Lin

J Med Chem· November 2020

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Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences.
Brian S Gerstenberger, Mary Ellen Banker, James D Clark, Martin E Dowty, Andrew Fensome, Brett D Hollingshead, Tsung H Lin

Sci Rep· June 2020

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Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1.
Andrew Fensome, Catherine M Ambler, Eric Arnold, Mary Ellen Banker, James D Clark, Tsung H Lin

Bioorg Med Chem· May 2020

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Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.
Martin E Dowty, Tsung H Lin, Michael I Jesson, Martin Hegen, David A Martin

Pharmacol Res Perspect· December 2019

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PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.
Hua Xu, Michael I Jesson, Uthpala I Seneviratne, Tsung H Lin, M Nusrat Sharif

ACS Chem Biol· June 2019

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Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841).
Andrew Fensome, Catherine M Ambler, Eric Arnold, Mary Ellen Banker, Matthew F Brown, Brett D Hollingshead, David Lin, Tsung H Lin

J Med Chem· October 2018

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Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.
Michael L Vazquez, Neelu Kaila, Joseph W Strohbach, John D Trzupek, Matthew F Brown, Tsung H Lin

J Med Chem· February 2018

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Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.
Atli Thorarensen, Martin E Dowty, Mary Ellen Banker, Brian Juba, Jason Jussif, Tsung Lin

J Med Chem· March 2017

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Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
Jean-Baptiste Telliez, Martin E Dowty, Lu Wang, Jason Jussif, Tsung Lin

ACS Chem Biol· December 2016

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Biomimetic Taste Receptors with Chiral Recognition by Photoluminescent Metal-Organic Frameworks Chelated with Polyaniline Helices.
Tu Lee, Tsung Yan Lin, Hung Lin Lee, Yun Hsuan Chang, Yee Chen Tsai

Chemistry· January 2016

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Proton-facilitated ammonia excretion by ionocytes of medaka (Oryzias latipes) acclimated to seawater.
Sian-Tai Liu, Lin Tsung, Jiun-Lin Horng, Li-Yih Lin

Am J Physiol Regul Integr Comp Physiol· August 2013

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pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood.
Ming Zhu, Susan Pleasic-Williams, Tsung H Lin, David A Wunderlich, John B Cheng

J Transl Med· March 2013

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Parametric modeling of cellular state transitions as measured with flow cytometry.
Hsiu J Ho, Tsung I Lin, Hannah H Chang, Steven B Haase, Sui Huang

BMC Bioinformatics· April 2012

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Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice.
Tsung H Lin, Martin Hegen, Elizabeth Quadros, Cheryl L Nickerson-Nutter, Kenneth C Appell, Scott H Schelling, Mary Collins

Arthritis Rheum· August 2010

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2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.
Andrew G Cole, Adolph C Bohnstedt, Vidyadhar Paradkar, Celia Kingsbury, Jorge G Quintero, Tsung H Lin

Bioorg Med Chem Lett· December 2009

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Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.
Min Shi, Tsung H Lin, Kenneth C Appell, Leslie J Berg

J Immunol· October 2009

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Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.
Laura L Rokosz, James R Beasley, Carolyn Diianni Carroll, Tsung Lin, Jiuqiao Zhao

Expert Opin Ther Targets· July 2008

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Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.
Min Shi, Tsung H Lin, Kenneth C Appell, Leslie J Berg

Immunity· June 2008

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