Publications by authors named "Tushar Tomar"

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Integrative Kinase Activity Profiling and Phosphoproteomics of Mouse Retina during cGMP-Dependent Retinal Degeneration.
Akanksha Roy, Jiaming Zhou, Merijn Nolet, Charlotte Welinder, Yu Zhu, Tushar Tomar

Int J Mol Sci· March 2024

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The PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration.
Arianna Tolone, Wadood Haq, Alexandra Fachinger, Akanksha Roy, Sandeep Kesh, Tushar Tomar

Int J Mol Sci· October 2023

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TGF-β promotes microtube formation in glioblastoma through thrombospondin 1.
Justin V Joseph, Capucine R Magaut, Simon Storevik, Luiz H Geraldo, Thomas Mathivet, Tushar Tomar

Neuro Oncol· April 2022

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Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.
Akanksha Roy, Arianna Tolone, Riet Hilhorst, John Groten, Tushar Tomar

Cell Death Discov· March 2022

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KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data.
Erica A K DePasquale, Khaled Alganem, Eduard Bentea, Nawshaba Nawreen, Jennifer L McGuire, Tushar Tomar

PLoS One· January 2022

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Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases.
Akanksha Roy, Riet Hilhorst, John Groten, François Paquet-Durand, Tushar Tomar

Curr Opin Pharmacol· October 2021

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Chick fetal organ spheroids as a model to study development and disease.
Soran Dakhel, Wayne I L Davies, Justin V Joseph, Tushar Tomar, Silvia Remeseiro

BMC Mol Cell Biol· July 2021

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Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration.
Akanksha Roy, John Groten, Valeria Marigo, Tushar Tomar, Riet Hilhorst

Int J Mol Sci· January 2021

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Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors.
Jiawan Wang, Kai Pollard, Amy N Allen, Tushar Tomar, Dirk Pijnenburg

Cancer Res· December 2020

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Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases.
Justin F Creeden, Khaled Alganem, Ali S Imami, F Charles Brunicardi, Shi-He Liu, Tushar Tomar

Int J Mol Sci· November 2020

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Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia.
Justin F Creeden, Khaled Alganem, Ali S Imami, Nicholas D Henkel, F Charles Brunicardi, Tushar Tomar

Int J Mol Sci· November 2020

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Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Joseph J Caumanns, Katrien Berns, G Bea A Wisman, Rudolf S N Fehrmann, Tushar Tomar

Clin Cancer Res· August 2018

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Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?
Martine C Morrison, Gopala K Yakala, Wen Liang, Peter Y Wielinga, Kanita Salic, Tushar Tomar

Sci Rep· June 2017

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Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer.
Tushar Tomar, Nicolette G Alkema, Leroy Schreuder, Gert Jan Meersma, Tim de Meyer

BMC Med· June 2017

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Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.
Tushar Tomar, Steven de Jong, Nicolette G Alkema, Rieks L Hoekman, Gert Jan Meersma

Genome Med· October 2016

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Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9.
Justin V Joseph, Ingrid A M van Roosmalen, Ellen Busschers, Tushar Tomar, Siobhan Conroy

PLoS One· July 2016

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Biobanking of patient and patient-derived xenograft ovarian tumour tissue: efficient preservation with low and high fetal calf serum based methods.
Nicolette G Alkema, Tushar Tomar, Evelien W Duiker, Gert Jan Meersma, Harry Klip

Sci Rep· October 2015

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Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis.
Justin V Joseph, Siobhan Conroy, Kirill Pavlov, Pallavi Sontakke, Tushar Tomar

Cancer Lett· April 2015

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Antibody-free LC-MS/MS quantification of rhTRAIL in human and mouse serum.
Daniel Wilffert, Carlos R Reis, Jos Hermans, Natalia Govorukhina, Tushar Tomar

Anal Chem· November 2013

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Selective targeting of interferon γ to stromal fibroblasts and pericytes as a novel therapeutic approach to inhibit angiogenesis and tumor growth.
Ruchi Bansal, Tushar Tomar, Arne Ostman, Klaas Poelstra, Jai Prakash

Mol Cancer Ther· November 2012

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