Publications by authors named "Ty D Troutman"

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Epigenetic and transcriptional programming of murine eosinophils in the esophagus.
Jennifer M Felton, Lee E Edsall, Ty D Troutman, Lydia Mack, Michael Kotliar

Nat Commun· November 2025

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Differential regulation of fetal bone marrow and liver hematopoiesis by yolk-sac-derived myeloid cells.
Benjamin Weinhaus, Shelli Homan, Morgan Kincaid, Aryan Tadwalkar, Xiaowei Gu, Ty D Troutman

Nat Commun· May 2025

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Eosinophil specialization is regulated by exposure to the esophageal epithelial microenvironment.
Julia L M Dunn, Andrea Szep, Emily Gonzalez Galan, Simin Zhang, Justin Marlman, Ty D Troutman

J Leukoc Biol· November 2024

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Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2.
Souradipta Ganguly, Sara Brin Rosenthal, Kei Ishizuka, Ty D Troutman, Theresa V Rohm

Proc Natl Acad Sci U S A· August 2024

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A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation.
Yohei Abe, Eric R Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J Spann, Ty D Troutman

Proc Natl Acad Sci U S A· January 2024

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Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis.
Steven P Proper, Alexander T Dwyer, Andrews Appiagyei, Jennifer M Felton, Netali Ben-Baruch Morgenstern, Ty D Troutman

Front Allergy· January 2024

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Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes.
Hunter Bennett, Ty D Troutman, Enchen Zhou, Nathanael J Spann, Verena M Link

Nat Immunol· November 2023

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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation.
Tzu-Yu Shao, Tony T Jiang, Joseph Stevens, Abigail E Russi, Ty D Troutman

Cell Rep· November 2023

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Breaking down the complex pathophysiology of eosinophilic esophagitis.
Brynne Underwood, Ty D Troutman, Justin T Schwartz

Ann Allergy Asthma Immunol· January 2023

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Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.
Kei-Ichiro Arimoto, Sayuri Miyauchi, Ty D Troutman, Yue Zhang, Mengdan Liu

Nat Commun· January 2023

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Exploiting dynamic enhancer landscapes to decode macrophage and microglia phenotypes in health and disease.
Ty D Troutman, Eric Kofman, Christopher K Glass

Mol Cell· October 2021

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Heterogeneity of HSCs in a Mouse Model of NASH.
Sara Brin Rosenthal, Xiao Liu, Souradipta Ganguly, Debanjan Dhar, Martina P Pasillas, Ty D Troutman

Hepatology· August 2021

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Epigenetic Regulation of Kupffer Cell Function in Health and Disease.
Hunter Bennett, Ty D Troutman, Mashito Sakai, Christopher K Glass

Front Immunol· June 2021

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An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells.
Lorane Texari, Nathanael J Spann, Ty D Troutman, Mashito Sakai, Jason S Seidman

STAR Protoc· March 2021

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Purification of mouse hepatic non-parenchymal cells or nuclei for use in ChIP-seq and other next-generation sequencing approaches.
Ty D Troutman, Hunter Bennett, Mashito Sakai, Jason S Seidman, Sven Heinz

STAR Protoc· March 2021

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TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation.
Ricardo A Irizarry-Caro, Margaret M McDaniel, Garrett R Overcast, Viral G Jain, Ty Dale Troutman

Proc Natl Acad Sci U S A· December 2020

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Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis.
Jason S Seidman, Ty D Troutman, Mashito Sakai, Anita Gola, Nathanael J Spann

Immunity· June 2020

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Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.
Xiaoli Sun, Jason S Seidman, Peng Zhao, Ty D Troutman, Nathanael J Spann

Cell Metab· January 2020

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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.
Mashito Sakai, Ty D Troutman, Jason S Seidman, Zhengyu Ouyang, Nathanael J Spann

Immunity· October 2019

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An upstream enhancer regulates expression in a tissue-specific manner.
Christopher M Allan, Patrick J Heizer, Yiping Tu, Norma P Sandoval, Rachel S Jung, Ty D Troutman

J Lipid Res· April 2019

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Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.
Spencer M Moore, Jason S Seidman, Jacob Ellegood, Richard Gao, Alex Savchenko, Ty D Troutman

Transl Psychiatry· January 2019

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BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation.
Krystin Deason, Ty Dale Troutman, Aakanksha Jain, Dilip K Challa, Rajakumar Mandraju

J Exp Med· September 2018

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Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.
Verena M Link, Sascha H Duttke, Hyun B Chun, Inge R Holtman, Emma Westin, Ty D Troutman

Cell· June 2018

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Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.
Evan D Muse, Shan Yu, Chantle R Edillor, Jenhan Tao, Nathanael J Spann, Ty D Troutman

Proc Natl Acad Sci U S A· May 2018

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Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages.
Dawn Z Eichenfield, Ty Dale Troutman, Verena M Link, Michael T Lam, Han Cho

Elife· July 2016

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