Publications by authors named "Tyler A Lesh"

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Differential effect of cannabis use and antipsychotic medication on extracellular free-water in the brain of individuals with early psychosis and controls.
Laura Martínez-Sadurní, Marta Barrera-Conde, Patricia Robledo, Emma Veza-Estevez, Jordi Garcia-Quintana, Tyler A Lesh

Mol Psychiatry· January 2026

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Test-retest reliability of template-defined vs. manual tracing processing streams in neuromelanin-sensitive magnetic resonance imaging analysis.
Tyler A Lesh, Jason Smucny, Joshua P Rhilinger, Sarvenaz Pakzad, Guillermo Horga

Neuroimage Rep· December 2025

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Qualitative Analysis of Telephone Logs: Client Engagement and Barriers to Completing an Initial Early Psychosis Assessment.
Adi Rosenthal, Monet S Meyer, Khalima Bolden-Thompson, Sarah Gobrial, Ruth Shim, Tyler A Lesh

Psychiatr Serv· May 2025

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Elevated Extracellular Free Water in the Brain Predicts Clinical Improvement in First-Episode Psychosis.
Tyler A Lesh, Daniel Bergé, Jason Smucny, Joyce Guo, Cameron S Carter

Biol Psychiatry Cogn Neurosci Neuroimaging· January 2025

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Predicting Clinical Improvement in Early Psychosis Using Circuit-Based Resting-State Functional Magnetic Resonance Imaging.
Jason Smucny, Tyler A Lesh, Marina D Albuquerque, Joshua P Rhilinger, Cameron S Carter

Schizophr Bull· November 2024

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Altered brain metabolites in male nonhuman primate offspring exposed to maternal immune activation.
Richard J Maddock, Roza M Vlasova, Shuai Chen, Ana-Maria Iosif, Jeffrey Bennett, Tyler A Lesh

Brain Behav Immun· October 2024

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Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.
Tracy L Warren, Justin D Tubbs, Tyler A Lesh, Mylena B Corona, Sarvenaz S Pakzad

Mol Psychiatry· August 2024

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Exploring the acceptability, barriers, and facilitators to psychosis screening in the integrated behavioral health primary care setting: a qualitative study.
Mark Savill, Rachel L Loewy, Sarah Gobrial, Julianna Kirkpatrick, A Jonathan Porteus, Tyler A Lesh

BMC Health Serv Res· August 2024

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Whole-brain intrinsic functional connectivity predicts symptoms and functioning in early psychosis.
Jason Smucny, Korey P Wylie, Tyler A Lesh, Cameron S Carter, Jason R Tregellas

J Psychiatr Res· July 2024

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The diagnostic accuracy of screening for psychosis spectrum disorders in behavioral health clinics integrated into primary care.
Mark Savill, Rachel L Loewy, Tara A Niendam, A Jonathan Porteus, Adi Rosenthal, Tyler A Lesh

Schizophr Res· April 2024

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Using Task-fMRI to Explore the Relationship Between Lifetime Cannabis Use and Cognitive Control in Individuals With First-Episode Schizophrenia.
Tyler A Lesh, Joshua Rhilinger, Rylee Brower, Alex M Mawla, J Daniel Ragland

Schizophr Bull Open· January 2024

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Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.
Tracy L Warren, Justin D Tubbs, Tyler A Lesh, Mylena B Corona, Sarvenaz Pakzad

medRxiv· November 2023

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Evidence for functional improvement in reward anticipation in recent onset schizophrenia after one year of coordinated specialty care.
Jason Smucny, Tyler A Lesh, Tara A Niendam, J Daniel Ragland, Laura M Tully

Psychol Med· October 2023

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Altered Associations Between Task Performance and Dorsolateral Prefrontal Cortex Activation During Cognitive Control in Schizophrenia.
Jason Smucny, Timothy D Hanks, Tyler A Lesh, Cameron S Carter

Biol Psychiatry Cogn Neurosci Neuroimaging· October 2023

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Extracellular free water elevations are associated with brain volume and maternal cytokine response in a longitudinal nonhuman primate maternal immune activation model.
Tyler A Lesh, Ana-Maria Iosif, Costin Tanase, Roza M Vlasova, Amy M Ryan

Mol Psychiatry· October 2023

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Increased Striatal Presynaptic Dopamine in a Nonhuman Primate Model of Maternal Immune Activation: A Longitudinal Neurodevelopmental Positron Emission Tomography Study With Implications for Schizophrenia.
Jason Smucny, Roza M Vlasova, Tyler A Lesh, Douglas J Rowland, Guobao Wang

Biol Psychiatry Cogn Neurosci Neuroimaging· May 2023

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Altered Associations Between Motivated Performance and Frontostriatal Functional Connectivity During Reward Anticipation in Schizophrenia.
Jason Smucny, Timothy D Hanks, Tyler A Lesh, Randall C O'Reilly, Cameron S Carter

Schizophr Bull· May 2023

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Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated Psychosis: A Cluster Randomized Clinical Trial.
Tara A Niendam, Rachel Loewy, Mark Savill, Kevin L Delucchi, Tyler A Lesh

JAMA Psychiatry· February 2023

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Data augmentation with Mixup: Enhancing performance of a functional neuroimaging-based prognostic deep learning classifier in recent onset psychosis.
Jason Smucny, Ge Shi, Tyler A Lesh, Cameron S Carter, Ian Davidson

Neuroimage Clin· December 2022

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Evidence of innate immune dysfunction in first-episode psychosis patients with accompanying mood disorder.
Heather K Hughes, Houa Yang, Tyler A Lesh, Cameron S Carter, Paul Ashwood

J Neuroinflammation· December 2022

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Improvement in prefrontal thalamic connectivity during the early course of the illness in recent-onset psychosis: a 12-month longitudinal follow-up resting-state fMRI study.
Daniel Bergé, Tyler A Lesh, Jason Smucny, Cameron S Carter

Psychol Med· October 2022

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Absence of altered in vivo concentration of dorsolateral prefrontal cortex GABA in recent onset schizophrenia.
Jong H Yoon, Richard J Maddock, Jeremy Laufer, Michael J Minzenberg, Tara A Niendam, Tyler A Lesh

Schizophr Res· May 2022

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Maternal Immune Activation during Pregnancy Alters Postnatal Brain Growth and Cognitive Development in Nonhuman Primate Offspring.
Roza M Vlasova, Ana-Maria Iosif, Amy M Ryan, Lucy H Funk, Takeshi Murai, Tyler A Lesh

J Neurosci· December 2021

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Schizophrenia and bipolar disorder are associated with opposite brain reward anticipation-associated response.
Jason Smucny, Laura M Tully, Amber M Howell, Tyler A Lesh, Sheri L Johnson

Neuropsychopharmacology· May 2021

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Differential Macrophage Responses in Affective Versus Non-Affective First-Episode Psychosis Patients.
Heather K Hughes, Emily Mills-Ko, Houa Yang, Tyler A Lesh, Cameron S Carter

Front Cell Neurosci· February 2021

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