Publications by authors named "Tyler D Ames"

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Partial mitochondrial involvement in the antiproliferative and immunostimulatory effects of PT-112.
Ruth Soler-Agesta, Manuel Beltrán-Visiedo, Ai Sato, Takahiro Yamazaki, Emma Guilbaud, Tyler D Ames

Oncoimmunology· December 2025

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A Phase I Clinical Study and In Vivo Findings with PT-112, a Novel Immunogenic Cell Death-Inducing Small Molecule, in Relapsed or Refractory Multiple Myeloma.
Taxiarchis Kourelis, Sikander Ailawadhi, Dan T Vogl, Sarah E Gibson, Meaghen E Sharik, Tyler D Ames

Clin Cancer Res· November 2025

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Comparative Effectiveness of Nonoperative Versus Operative Treatment of Completely Displaced Clavicle Shaft Fractures Among Children.
Tyler D Ames, Charles T Mehlman, Robert Toy, Shital N Parikh

Orthopedics· November 2022

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PT-112 Induces Mitochondrial Stress and Immunogenic Cell Death, Targeting Tumor Cells with Mitochondrial Deficiencies.
Ruth Soler-Agesta, Joaquín Marco-Brualla, Martha Minjárez-Sáenz, Christina Y Yim, Marta Martínez-Júlvez, Tyler D Ames

Cancers (Basel)· August 2022

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Phase I study of PT-112, a novel pyrophosphate-platinum immunogenic cell death inducer, in advanced solid tumours.
Daniel D Karp, D Ross Camidge, Jeffery R Infante, Tyler D Ames, Matthew R Price

EClinicalMedicine· July 2022

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PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models.
Takahiro Yamazaki, Aitziber Buqué, Tyler D Ames, Lorenzo Galluzzi

Oncoimmunology· July 2021

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Bilateral thigh and knee pain · leg weakness · no history of trauma · Dx?
Tyler D Ames, Carmen E Quatman, Laura S Phieffer, Scott Van Steyn

J Fam Pract· April 2018

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Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions.
Zasha Weinberg, Christina E Lünse, Keith A Corbino, Tyler D Ames, James W Nelson

Nucleic Acids Res· October 2017

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Quantitative Trait Loci (QTL)-Guided Metabolic Engineering of a Complex Trait.
Matthew J Maurer, Lawrence Sutardja, Dominic Pinel, Stefan Bauer, Amanda L Muehlbauer, Tyler D Ames

ACS Synth Biol· March 2017

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Clinical assessment tools identify functional deficits in fragility fracture patients.
Tyler D Ames, Corinne E Wee, Khoi M Le, Tiffany L Wang, Julie Y Bishop

Clin Interv Aging· February 2017

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Fear of Falling Correlates with Subtle Neuromuscular Balance and Strength Deficits of Fragility Fracture Patients.
Corinne E Wee, Tyler D Ames, Khoi M Le, Tiffany Wang, Laura S Phieffer

Aging Dis· October 2016

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Training Advanced Practice Providers to Collect Functional Outcomes After Fragility Fractures.
Tiffany L Wang, Tyler D Ames, Khoi M Le, Corinne Wee, Laura S Phieffer

Geriatr Orthop Surg Rehabil· September 2015

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Small molecule fluoride toxicity agonists.
James W Nelson, Mark S Plummer, Kenneth F Blount, Tyler D Ames, Ronald R Breaker

Chem Biol· April 2015

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A widespread self-cleaving ribozyme class is revealed by bioinformatics.
Adam Roth, Zasha Weinberg, Andy G Y Chen, Peter B Kim, Tyler D Ames

Nat Chem Biol· January 2014

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Bacterial aptamers that selectively bind glutamine.
Tyler D Ames, Ronald R Breaker

RNA Biol· September 2011

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A eubacterial riboswitch class that senses the coenzyme tetrahydrofolate.
Tyler D Ames, Dmitry A Rodionov, Zasha Weinberg, Ronald R Breaker

Chem Biol· July 2010

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Structural basis of ligand binding by a c-di-GMP riboswitch.
Kathryn D Smith, Sarah V Lipchock, Tyler D Ames, Jimin Wang, Ronald R Breaker

Nat Struct Mol Biol· December 2009

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A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria.
Elena Poiata, Michelle M Meyer, Tyler D Ames, Ronald R Breaker

RNA· November 2009

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Identification of candidate structured RNAs in the marine organism 'Candidatus Pelagibacter ubique'.
Michelle M Meyer, Tyler D Ames, Daniel P Smith, Zasha Weinberg, Michael S Schwalbach

BMC Genomics· June 2009

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Engineering high-speed allosteric hammerhead ribozymes.
Kristian H Link, Lixia Guo, Tyler D Ames, Laising Yen, Richard C Mulligan

Biol Chem· August 2007

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