Publications by authors named "Tyler G Demarest"

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NAD in Aging: Molecular Mechanisms and Translational Implications.
Evandro F Fang, Sofie Lautrup, Yujun Hou, Tyler G Demarest, Deborah L Croteau, Mark P Mattson, Vilhelm A Bohr

October 2017

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Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair-Deficient 3xTg/POLβ Alzheimer Disease Mouse Model.
Robert Pawlosky, Tyler G Demarest, M Todd King, Darlene Estrada, Richard L Veech

J Neurochem· January 2025

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Translation of gene therapy strategies for amyotrophic lateral sclerosis.
Tyler G Demarest, Maria Grazia Biferi

Trends Mol Med· September 2022

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Self-assembly of multi-component mitochondrial nucleoids via phase separation.
Marina Feric, Tyler G Demarest, Jane Tian, Deborah L Croteau, Vilhelm A Bohr

EMBO J· March 2021

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Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction.
Chongkui Sun, Kun Wang, Amanda J Stock, Yi Gong, Tyler G Demarest

EMBO J· November 2020

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Biological sex and DNA repair deficiency drive Alzheimer's disease via systemic metabolic remodeling and brain mitochondrial dysfunction.
Tyler G Demarest, Vijay R Varma, Darlene Estrada, Mansi Babbar, Sambuddha Basu

Acta Neuropathol· July 2020

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Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation.
Mustafa N Okur, Jong-Hyuk Lee, Wasif Osmani, Risako Kimura, Tyler G Demarest

Nucleic Acids Res· March 2020

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NAD augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Evandro F Fang, Yujun Hou, Sofie Lautrup, Martin Borch Jensen, Beimeng Yang, Tyler G Demarest

Nat Commun· November 2019

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Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging.
Jong-Hyuk Lee, Tyler G Demarest, Mansi Babbar, Edward W Kim, Mustafa N Okur

Nucleic Acids Res· September 2019

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Mitochondria, Oxytocin, and Vasopressin: Unfolding the Inflammatory Protein Response.
Evan A Bordt, Caroline J Smith, Tyler G Demarest, Staci D Bilbo, Marcy A Kingsbury

Neurotox Res· August 2019

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High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs.
T Chase Francis, Hideaki Yano, Tyler G Demarest, Hui Shen, Antonello Bonci

Neuron· August 2019

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Assessment of NADmetabolism in human cell cultures, erythrocytes, cerebrospinal fluid and primate skeletal muscle.
Tyler G Demarest, Gia Thinh D Truong, Jacqueline Lovett, Joy G Mohanty, Julie A Mattison

Anal Biochem· May 2019

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Toward understanding genomic instability, mitochondrial dysfunction and aging.
Nima B Fakouri, Yujun Hou, Tyler G Demarest, Louise S Christiansen, Mustafa N Okur

FEBS J· March 2019

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mGluR2/3 activation of the SIRT1 axis preserves mitochondrial function in diabetic neuropathy.
Krish Chandrasekaran, Anjaneyulu Muragundla, Tyler G Demarest, Joungil Choi, Avinash R Sagi

Ann Clin Transl Neurol· December 2017

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Sex-dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy.
Tyler G Demarest, Rosemary A Schuh, Jaylyn Waddell, Mary C McKenna, Gary Fiskum

J Neurochem· June 2016

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Sex differences in mitochondrial (dys)function: Implications for neuroprotection.
Tyler G Demarest, Margaret M McCarthy

J Bioenerg Biomembr· April 2015

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Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity.
Joungil Choi, Krish Chandrasekaran, Tyler G Demarest, Tibor Kristian, Su Xu

Ann Clin Transl Neurol· August 2014

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Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan(®) low density array.
Tyler G Demarest, Nivetha Murugesan, Bandana Shrestha, Joel S Pachter

J Neurosci Methods· August 2012

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Brain regional angiogenic potential at the neurovascular unit during normal aging.
Nivetha Murugesan, Tyler G Demarest, Joseph A Madri, Joel S Pachter

Neurobiol Aging· May 2012

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