Publications by authors named "Tyler Hether"

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C Melms, Sebastian Niezen, Tyler Hether

Genome Biol· March 2025

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C Melms, Sebastian Niezen, Tyler Hether

bioRxiv· October 2022

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SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice.
Kenneth H Dinnon, Sarah R Leist, Kenichi Okuda, Hong Dang, Ethan J Fritch, Tyler Hether

Sci Transl Med· September 2022

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PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial.
Vivek Narayan, Julie S Barber-Rotenberg, In-Young Jung, Simon F Lacey, Andrew J Rech, Tyler D Hether

Nat Med· April 2022

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A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies.
Kenneth H Dinnon, Sarah R Leist, Kenichi Okuda, Hong Dang, Ethan J Fritch, Tyler Hether

bioRxiv· February 2022

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System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Jiwoon Park, Jonathan Foox, Tyler Hether, David C Danko, Sarah Warren

Cell Rep Med· February 2022

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Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb.
Mona Khan, Seung-Jun Yoo, Marnick Clijsters, Wout Backaert, Arno Vanstapel, Tyler D Hether

Cell· November 2021

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The tumor immune microenvironment of primary and metastatic HER2- positive breast cancers utilizing gene expression and spatial proteomic profiling.
Ilana Schlam, Sarah E Church, Tyler D Hether, Krysta Chaldekas, Briana M Hudson

J Transl Med· November 2021

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer.
William A Freed-Pastor, Laurens J Lambert, Zackery A Ely, Nimisha B Pattada, Arjun Bhutkar, Tyler D Hether

Cancer Cell· October 2021

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COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Toni M Delorey, Carly G K Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Tyler Hether

Nature· July 2021

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The spatial landscape of lung pathology during COVID-19 progression.
André F Rendeiro, Hiranmayi Ravichandran, Yaron Bram, Vasuretha Chandar, Junbum Kim, Tyler Hether

Nature· May 2021

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Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.
Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel Rosiene, Tyler D Hether

Nat Commun· March 2021

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Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.
Jiwoon Park, Jonathan Foox, Tyler Hether, David Danko, Sarah Warren

bioRxiv· March 2021

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A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.
Toni M Delorey, Carly G K Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Tyler Hether

bioRxiv· February 2021

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Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy.
Philip A Thompson, Jaya Srivastava, Christine Peterson, Paolo Strati, Jeffrey L Jorgensen, Tyler Hether

Blood· November 2019

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Identifying and Tracking Low-Frequency Virus-Specific TCR Clonotypes Using High-Throughput Sequencing.
Kyle Wolf, Tyler Hether, Pavlo Gilchuk, Amrendra Kumar, Ahmad Rajeh

Cell Rep· November 2018

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Correction: Cryptic chytridiomycosis linked to climate and genetic variation in amphibian populations of the southeastern United States.
Ariel A Horner, Eric A Hoffman, Matthew R Tye, Tyler D Hether, Anna E Savage

PLoS One· October 2017

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Cryptic chytridiomycosis linked to climate and genetic variation in amphibian populations of the southeastern United States.
Ariel A Horner, Eric A Hoffman, Matthew R Tye, Tyler D Hether, Anna E Savage

PLoS One· September 2017

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Genetic regulatory network motifs constrain adaptation through curvature in the landscape of mutational (co)variance.
Tyler D Hether, Paul A Hohenlohe

Evolution· April 2014

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Goldilocks Meets Santa Rosalia: An Ephemeral Speciation Model Explains Patterns of Diversification Across Time Scales.
Erica Bree Rosenblum, Brice A J Sarver, Joseph W Brown, Simone Des Roches, Kayla M Hardwick, Tyler D Hether

Evol Biol· June 2012

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Fat frogs, mobile genes: unexpected phylogeographic patterns for the ornate chorus frog (Pseudacris ornata).
Jacob F Degner, Diana M Silva, Tyler D Hether, Juan M Daza, Eric A Hoffman

Mol Ecol· June 2010

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Permanent Genetic Resources added to Molecular Ecology Resources Database 1 August 2009-30 September 2009.

Mol Ecol Resour· January 2010

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Eight novel tetranucleotide and five cross-species dinucleotide microsatellite loci for the ornate chorus frog (Pseudacris ornata).
Jacob F Degner, Tyler D Hether, Eric A Hoffman

Mol Ecol Resour· March 2009

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