Publications by authors named "Tyler Nygaard"

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Hemolysis of Human Erythrocytes by Methicillin-Resistant Is Primarily Caused by PSMα Peptides.
Tyler K Nygaard, Annika Gao, Eliot LaTray, Jovanka M Voyich

Toxins (Basel)· October 2025

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The Susceptibility Profiles of Human Peripheral Blood Cells to Cytotoxins.
Tyler K Nygaard, Jovanka M Voyich

Microorganisms· August 2025

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SaeR/S-regulated factors overcome human complement-mediated inhibition of aggregation to evade neutrophil killing.
Brian A Pettygrove, Tyler K Nygaard, Timothy R Borgogna, Natalia Malachowa, Gauri Gaur

Proc Natl Acad Sci U S A· May 2025

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The Relative Importance of Cytotoxins Produced by Methicillin-Resistant Strain USA300 for Causing Human PMN Destruction.
Tyler K Nygaard, Timothy R Borgogna, Kyler B Pallister, Maria Predtechenskaya, Owen S Burroughs

Microorganisms· August 2024

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The Accessory Gene of the SaeR/S Two-Component Gene Regulatory System Impacts Virulence During Neutrophil Interaction.
Madison M Collins, Ranjan K Behera, Kyler B Pallister, Tyler J Evans, Owen Burroughs, Tyler K Nygaard

Front Microbiol· April 2020

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Quantifying the Cytotoxicity of Staphyloccus aureus Against Human Polymorphonuclear Leukocytes.
Jennifer G Dankoff, Kyler B Pallister, Fermin E Guerra, Alexander J Parks, Kelly Gorham, Tyler K Nygaard

J Vis Exp· January 2020

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Aspartic Acid Residue 51 of SaeR Is Essential for Virulence.
Tyler K Nygaard, Timothy R Borgogna, Eli W Sward, Fermin E Guerra, Jennifer G Dankoff

Front Microbiol· December 2018

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Staphylococcus aureus SaeR/S-Regulated Factors Decrease Monocyte-Derived Tumor Necrosis Factor-α to Reduce Neutrophil Bactericidal Activity.
Eli W Sward, Elizabeth M Fones, Russel R Spaan, Kyler B Pallister, Brandon L Haller, Tyler K Nygaard

J Infect Dis· March 2018

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Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation.
Seitaro Nakagawa, Masanori Matsumoto, Yuki Katayama, Rena Oguma, Seiichiro Wakabayashi, Tyler Nygaard

Cell Host Microbe· November 2017

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Interaction of Staphylococci with Human B cells.
Tyler K Nygaard, Scott D Kobayashi, Brett Freedman, Adeline R Porter, Jovanka M Voyich

PLoS One· June 2017

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Bovine CCL28 Mediates Chemotaxis via CCR10 and Demonstrates Direct Antimicrobial Activity against Mastitis Causing Bacteria.
Kyler B Pallister, Sara Mason, Tyler K Nygaard, Bin Liu, Shannon Griffith

PLoS One· June 2016

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The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus.
Oliwia W Zurek, Tyler K Nygaard, Robert L Watkins, Kyler B Pallister, Victor J Torres

J Innate Immun· October 2014

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The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300.
Tyler K Nygaard, Kyler B Pallister, Oliwia W Zurek, Jovanka M Voyich

J Leukoc Biol· November 2013

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Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor.
Michael E Olson, Tyler K Nygaard, Laynez Ackermann, Robert L Watkins, Oliwia W Zurek

Infect Immun· April 2013

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Alpha-toxin induces programmed cell death of human T cells, B cells, and monocytes during USA300 infection.
Tyler K Nygaard, Kyler B Pallister, Ashley L DuMont, Mark DeWald, Robert L Watkins

PLoS One· September 2012

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Rot and SaeRS cooperate to activate expression of the staphylococcal superantigen-like exoproteins.
Meredith A Benson, Sarit Lilo, Tyler Nygaard, Jovanka M Voyich, Victor J Torres

J Bacteriol· August 2012

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Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis.
Ashley L Dumont, Tyler K Nygaard, Robert L Watkins, Amanda Smith, Lina Kozhaya

Mol Microbiol· February 2011

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Spectroscopic identification of heme axial ligands in HtsA that are involved in heme acquisition by Streptococcus pyogenes.
Yanchao Ran, Mengyao Liu, Hui Zhu, Tyler K Nygaard, Doreen E Brown

Biochemistry· April 2010

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SaeR binds a consensus sequence within virulence gene promoters to advance USA300 pathogenesis.
Tyler K Nygaard, Kyler B Pallister, Peter Ruzevich, Shannon Griffith, Cuong Vuong

J Infect Dis· January 2010

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The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus.
Jovanka M Voyich, Cuong Vuong, Mark DeWald, Tyler K Nygaard, Stanislava Kocianova

J Infect Dis· June 2009

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Community-associated methicillin-resistant Staphylococcus aureus skin infections: advances toward identifying the key virulence factors.
Tyler K Nygaard, Frank R DeLeo, Jovanka M Voyich

Curr Opin Infect Dis· April 2008

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Identification and characterization of the heme-binding proteins SeShp and SeHtsA of Streptococcus equi subspecies equi.
Tyler K Nygaard, Mengyao Liu, Michael J McClure, Benfang Lei

BMC Microbiol· September 2006

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The mechanism of direct heme transfer from the streptococcal cell surface protein Shp to HtsA of the HtsABC transporter.
Tyler K Nygaard, George C Blouin, Mengyao Liu, Maki Fukumura, John S Olson

J Biol Chem· July 2006

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