Publications by authors named "Tyler R Simpson"

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Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson

Cancer Cell· December 2015

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Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility.
Tsvetelina Pentcheva-Hoang, Tyler R Simpson, Welby Montalvo-Ortiz, James P Allison

Cancer Immunol Res· October 2014

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson

Cancer Cell· June 2014

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Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.
Tyler R Simpson, Fubin Li, Welby Montalvo-Ortiz, Manuel A Sepulveda, Katharina Bergerhoff

J Exp Med· August 2013

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Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication.
Sergio A Quezada, Karl S Peggs, Tyler R Simpson, James P Allison

Immunol Rev· May 2011

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Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS).
Tyler R Simpson, Sergio A Quezada, James P Allison

Curr Opin Immunol· June 2010

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Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts.
Sergio A Quezada, Tyler R Simpson, Karl S Peggs, Taha Merghoub, Jelena Vider

J Exp Med· March 2010

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Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma.
Sergio A Quezada, Karl S Peggs, Tyler R Simpson, Yuelei Shen, Dan R Littman

J Exp Med· September 2008

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