Publications by authors named "Tzu-Ching Meng"

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Enrichment of mutant calmodulin protein in a murine model of a human calmodulinopathy.
Wen-Chin Tsai, Chiu-Fen Yang, Shu-Yu Lin, Suh-Yuen Liang, Wei-Chung Tsai, Tzu-Ching Meng

JCI Insight· September 2025

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Single-cell signaling network profiling during redox stress reveals dynamic redox regulation in immune cells.
Yi-Chuan Wang, Ping-Hsun Wu, Wen-Chieh Ting, Yi-Fu Wang, Ming-Han Yang, Tzu-Ching Meng

Nat Commun· July 2025

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Gut colonization of suppresses colitis-associated colon cancer development.
Hung-Lin Chen, Po-Yuan Hu, Chang-Shan Chen, Wei-Han Lin, Daniel K Hsu, Tzu-Ching Meng

Microbiol Spectr· February 2025

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Pharmacological inhibition of the Src homology phosphatase 2 confers partial protection in a mouse model of alcohol-associated liver disease.
Ming-Fo Hsu, Shinichiro Koike, Chang-Shan Chen, Sonia M Najjar, Tzu-Ching Meng

Biomed Pharmacother· June 2024

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Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte.
Ming-Fo Hsu, Yoshihiro Ito, Jai Prakash Singh, Shu-Fang Hsu, Alan Wells, Tzu-Ching Meng

Biochim Biophys Acta Mol Cell Res· January 2024

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High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha.
Yu-Chun Chien, Yong-Sheng Wang, Deepa Sridharan, Chu-Wei Kuo, Chih-Ta Chien, Tzu-Ching Meng

JACS Au· July 2023

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Application of hybrid biophysical-biochemical methods to unravel the molecular basis for auto-inhibition and activation of protein tyrosine phosphatase TCPTP/PTPN2.
Jai Prakash Singh, Yi-Yun Chen, Yu-Ting Huang, Shang-Te Danny Hsu, Tzu-Ching Meng

Methods Enzymol· March 2023

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Active-site cysteine 215 sulfonation targets protein tyrosine phosphatase PTP1B for Cullin1 E3 ligase-mediated degradation.
Chun-Yi Yang, Chiu-Fen Yang, Xiao-Fang Tang, Luciana E S F Machado, Jai Prakash Singh, Tzu-Ching Meng

Free Radic Biol Med· January 2023

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The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1.
Jai Prakash Singh, Yang Li, Yi-Yun Chen, Shang-Te Danny Hsu, Rebecca Page, Tzu-Ching Meng

Nat Commun· January 2022

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Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity.
Jai Prakash Singh, Meng-Jung Lin, Shu-Fang Hsu, Wolfgang Peti, Cheng-Chung Lee, Tzu-Ching Meng

Biochemistry· December 2021

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Eating right for a healthier heart: Food choice contributes to cardiometabolic benefits and reduction of carotid intima-media thickness.
Chiu-Fen Yang, Tsung-Jen Lin, Chin-Hung Liu, Yu-Chih Chen, Sheau-Chung Tang, Tzu-Ching Meng

Nutrition· October 2020

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Targeting protein tyrosine phosphatase PTP-PEST (PTPN12) for therapeutic intervention in acute myocardial infarction.
Chiu-Fen Yang, Yi-Yun Chen, Jai Prakash Singh, Shu-Fang Hsu, Yu-Wen Liu, Tzu-Ching Meng

Cardiovasc Res· April 2020

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Nitrite Protects Neurons Against Hypoxic Damage Through -nitrosylation of Caspase-6.
Yen-Jung Chen, Yun-Chung Liu, Yu-Wen Liu, Yu-Bin Lee, Hsin-Chieh Huang, Tzu-Ching Meng

Antioxid Redox Signal· July 2019

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PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
Angel Bottini, Dennis J Wu, Rizi Ai, Michelle Le Roux, Beatrix Bartok, Tzu-Ching Meng

Ann Rheum Dis· May 2019

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Dual specificity phosphatase DUSP6 promotes endothelial inflammation through inducible expression of ICAM-1.
Shu-Fang Hsu, Yu-Bin Lee, Ying-Chu Lee, Ai-Ling Chung, Maria Karmella Apaya, Tzu-Ching Meng

FEBS J· May 2018

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Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants.
Lee F Willoughby, Jan Manent, Kirsten Allan, Han Lee, Marta Portela, Tzu-Ching Meng

FEBS J· July 2017

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Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Yan-Jiun Huang, Ching-Kuo Yang, Po-Li Wei, Thanh-Tuan Huynh, Jacqueline Whang-Peng, Tzu-Ching Meng

J Hematol Oncol· February 2017

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Interactive role of diabetes mellitus and female sex in the risk of cholangiocarcinoma: A population-based nested case-control study.
Yan-Jiun Huang, Alexander Th Wu, Hung-Yi Chiou, Ming-Tsang Chuang, Tzu-Ching Meng

Oncotarget· January 2017

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S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling.
Ming-Fo Hsu, Kuan-Ting Pan, Fan-Yu Chang, Kay-Hooi Khoo, Henning Urlaub, Tzu-Ching Meng

Free Radic Biol Med· October 2016

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Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Kai-En Chen, Meng-Yen Li, Chia-Cheng Chou, Meng-Ru Ho, Guang-Chao Chen, Tzu-Ching Meng

Structure· April 2015

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A Drosophila-centric view of protein tyrosine phosphatases.
Teri Hatzihristidis, Nikita Desai, Andrew P Hutchins, Tzu-Ching Meng, Michel L Tremblay

FEBS Lett· April 2015

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Negative regulation of MAP kinase signaling in Drosophila by Ptp61F/PTP1B.
Stéphane Tchankouo-Nguetcheu, Mario Udinotti, Marjorie Durand, Tzu-Ching Meng, Mohammed Taouis

Mol Genet Genomics· October 2014

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Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation.
Kai-En Chen, Shu-Yu Lin, Mei-Ju Wu, Meng-Ru Ho, Abirami Santhanam, Tzu-Ching Meng

Sci Signal· October 2014

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Ecdysone-induced receptor tyrosine phosphatase PTP52F regulates Drosophila midgut histolysis by enhancement of autophagy and apoptosis.
Abirami Santhanam, Wen-Hsin Peng, Ya-Ting Yu, Tzu-Kang Sang, Guang-Chao Chen, Tzu-Ching Meng

Mol Cell Biol· May 2014

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Mass spectrometry-based quantitative proteomics for dissecting multiplexed redox cysteine modifications in nitric oxide-protected cardiomyocyte under hypoxia.
Kuan-Ting Pan, Yi-Yun Chen, Tsung-Hsien Pu, Yu-Shu Chao, Chun-Yi Yang, Tzu-Ching Meng

Antioxid Redox Signal· March 2014

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