Publications by authors named "Tzu-Ping Ko"

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Structural basis of enhanced stalling efficiency of an engineered ribosome arrest peptide.
Manoj Kumar Sriramoju, Tzu-Ping Ko, Piotr Draczkowski, Shang-Te Danny Hsu

Nucleic Acids Res· October 2025

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Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase.
Sheng-Wei Lin, Tzu-Ping Ko, Hung-Yu Chiang, Cheng-Guo Wu, Min-Feng Hsu

J Biol Chem· April 2025

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Site-Specific Histidine Aza-Michael Addition in Proteins Enabled by a Ferritin-Based Metalloenzyme.
Jo-Chu Tsou, Chun-Ju Tsou, Chun-Hsiung Wang, An-Li A Ko, Yi-Hui Wang, Tzu-Ping Ko

J Am Chem Soc· December 2024

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The QS regulator AphB promotes expression of the AHPND PirA and PirB toxins and may enhance virulence under acidic conditions.
Shin-Jen Lin, Phuoc Thien Le, Yuan-Chih Chang, Chang-Yi Liu, Yu-Hsuan Chen, Tzu-Ping Ko

Int J Biol Macromol· December 2024

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A distinct dimer configuration of a diatom Get3 forming a tetrameric complex with its tail-anchored membrane cargo.
Chi-Chih Chen, Yu-Ru Huang, Yuen Ting Chan, Hung-Yun Lin, Han-Jia Lin, Tzu-Ping Ko

BMC Biol· June 2024

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Dual dimeric interactions in the nucleic acid-binding protein Sac10b lead to multiple bridging of double-stranded DNA.
Songqiang Tang, Chun-Hsiang Huang, Tzu-Ping Ko, Kuan-Fu Lin, Yuan-Chih Chang

Heliyon· June 2024

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Structural insights into the molecular mechanism of phytoplasma immunodominant membrane protein.
Chang Yi Liu, Han Pin Cheng, Chan Pin Lin, Yi Ting Liao, Tzu Ping Ko

IUCrJ· May 2024

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K2 capsular polysaccharide degradation by a bacteriophage depolymerase does not require trimer formation.
Ting-Juan Ye, Kit-Man Fung, I-Ming Lee, Tzu-Ping Ko, Chia-Yi Lin

mBio· March 2024

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Mechanistic Insights into Dibasic Iminosugars as pH-Selective Pharmacological Chaperones to Stabilize Human α-Galactosidase.
Huang-Yi Li, Hung-Yi Lin, Sheng-Kai Chang, Yu-Ting Chiu, Chung-Chien Hou, Tzu-Ping Ko

JACS Au· March 2024

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Structure, dynamics, and stability of the smallest and most complex 7 protein knot.
Min-Feng Hsu, Manoj Kumar Sriramoju, Chih-Hsuan Lai, Yun-Ru Chen, Jing-Siou Huang, Tzu-Ping Ko

J Biol Chem· January 2024

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Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN.
Hsi-Wen Kao, Wei-Lin Lu, Meng-Ru Ho, Yu-Fong Lin, Yun-Jung Hsieh, Tzu-Ping Ko

ACS Synth Biol· August 2023

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Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Chia-Shin Yang, Tzu-Ping Ko, Chao-Jung Chen, Mei-Hui Hou, Yu-Chuan Wang

Nat Commun· August 2023

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Cryo-EM reveals the structure and dynamics of a 723-residue malate synthase G.
Meng-Ru Ho, Yi-Ming Wu, Yen-Chen Lu, Tzu-Ping Ko, Kuen-Phon Wu

J Struct Biol· June 2023

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Multiple Nucleocapsid Structural Forms of Shrimp White Spot Syndrome Virus Suggests a Novel Viral Morphogenetic Pathway.
Hui-Ju Huang, Sen-Lin Tang, Yuan-Chih Chang, Hao-Ching Wang, Tze Hann Ng, Kyoko Matoba, Tzu-Ping Ko

Int J Mol Sci· April 2023

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Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Ting Juan Ye, Kai Fa Huang, Tzu Ping Ko, Shih Hsiung Wu

Acta Crystallogr D Struct Biol· May 2022

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Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors.
Ching-Chih Lin, Sin Yong Hoo, Li-Ting Ma, Chih Lin, Kai-Fa Huang, Tzu-Ping Ko

Commun Biol· May 2022

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Structural insights into the substrate selectivity of α-oxoamine synthases from marine Vibrio sp. QWI-06.
Hsin-Yang Chang, Li-Hua Lo, Yu-Hsuan Lan, Mao-Xuan Hong, Yuen Ting Chan, Tzu-Ping Ko

Colloids Surf B Biointerfaces· February 2022

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Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use.
I-Fan Tu, Tzu-Lung Lin, Feng-Ling Yang, I-Ming Lee, Wei-Lin Tu, Tzu-Ping Ko

J Biomed Sci· February 2022

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Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
Sei-Hyun Choi, Byungsun Jeon, Namho Kim, Hsin-Hui Wu, Tzu-Ping Ko

J Am Chem Soc· December 2021

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A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
Kai-Fa Huang, Jing-Siou Huang, Mao-Lun Wu, Wan-Ling Hsieh, Kai-Cheng Hsu, Tzu-Ping Ko

J Mol Biol· June 2021

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Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Tzu-Ping Ko, Yu-Chuan Wang, Chia-Ling Tsai, Chia-Shin Yang, Mei-Hui Hou

Nucleic Acids Res· May 2021

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Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site.
Chia-Shin Yang, Wei-Chien Huang, Tzu-Ping Ko, Yu-Chuan Wang, Andrew H-J Wang

Biochem Biophys Res Commun· January 2021

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Cloning, expression, identification and characterization of borneol dehydrogenase isozymes in Pseudomonas sp. TCU-HL1.
Aye Aye Khine, Pei-Chieh Lu, Tzu-Ping Ko, Kai-Fa Huang, Hao-Ping Chen

Protein Expr Purif· November 2020

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Structural insights into thebaine synthase 2 catalysis.
Chun-Chi Chen, Jing Xue, Wei Peng, Binju Wang, Lilan Zhang, Tzu-Ping Ko

Biochem Biophys Res Commun· August 2020

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