Publications by authors named "Tzuling Cheng"

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Pharmacokinetics, pharmacodynamics and safety of casdatifan, a novel hypoxia-inducible factor-2α inhibitor, in healthy participants.
Mohammad Ghasemi, Ji Yun Kim, Lisa Seitz, Lixia Jin, Paul G Foster, Tzuling Cheng

Br J Clin Pharmacol· December 2025

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Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells.
Juan de Los Santos-Jiménez, José A Campos-Sandoval, Clara Márquez-Torres, Nieves Urbano-Polo, David Brøndegaard, Tzuling Cheng

J Biomed Sci· February 2021

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Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385).
Paul M Wehn, James P Rizzi, Darryl D Dixon, Jonas A Grina, Stephen T Schlachter, Tzuling Cheng

J Med Chem· November 2018

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A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma.
Eli M Wallace, James P Rizzi, Guangzhou Han, Paul M Wehn, Zhaodan Cao, Tzuling Cheng

Cancer Res· September 2016

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Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.
Mercedes Martín-Rufián, Renata Nascimento-Gomes, Ana Higuero, Amanda R Crisma, José A Campos-Sandoval, Tzuling Cheng

J Mol Med (Berl)· March 2014

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Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng

Nature· November 2011

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Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Tzuling Cheng, Jessica Sudderth, Chendong Yang, Andrew R Mullen, Eunsook S Jin

Proc Natl Acad Sci U S A· May 2011

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TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Yi-Hung Ou, Michael Torres, Rosalyn Ram, Etienne Formstecher, Christina Roland, Tzuling Cheng

Mol Cell· February 2011

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RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.
Brian O Bodemann, Anthony Orvedahl, Tzuling Cheng, Rosalyn R Ram, Yi-Hung Ou

Cell· January 2011

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Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling.
Kakajan Komurov, David Padron, Tzuling Cheng, Michael Roth, Kevin P Rosenblatt

J Biol Chem· July 2010

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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Sung Chan Kim, Robert Sprung, Yue Chen, Yingda Xu, Haydn Ball, Tzuling Cheng

Mol Cell· August 2006

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Doxycycline- and tetracycline-regulated transcriptional silencer enhance the expression level and transactivating performance of rtTA.
Jen-Feng Lai, Hsin-Yuan Cheng, Tzu-Ling Cheng, Yu-Yu Lin, Li-Chieh Chen

J Gene Med· December 2004

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Regulation of anoikis by Cdc42 and Rac1.
Tzu-Ling Cheng, Marc Symons, Tzuu-Shuh Jou

Exp Cell Res· May 2004

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An ecdysone and tetracycline dual regulatory expression system for studies on Rac1 small GTPase-mediated signaling.
Jen-Feng Lai, Shin-Hun Juang, Yi-Mei Hung, Hsin-Yuan Cheng, Tzu-Ling Cheng

Am J Physiol Cell Physiol· September 2003

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