Publications by authors named "U Mende"

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Computationally informed point of departure evaluation for proarrhythmic cardiotoxicity assessment using 3D engineered cardiac microtissues from human iPSC-derived cardiomyocytes.
Mark C Daley, Peter Bronk, Tae Yun Kim, Arvin H Soepriatna, Cao T Tran, Ulrike Mende

Toxicol Sci· September 2025

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In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment.
Mark C Daley, Marjory Moreau, Peter Bronk, Jeffrey Fisher, Celinda M Kofron, Ulrike Mende

Toxicol Sci· September 2024

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Mitochondrial Ca uniporter (MCU) variants form plasma-membrane channels.
Iuliia Polina, Jyotsna Mishra, Michael W Cypress, Maria Landherr, Nedyalka Valkov, Ulrike Mende

bioRxiv· August 2023

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Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues.
Arvin H Soepriatna, Allison Navarrete-Welton, Tae Yun Kim, Mark C Daley, Peter Bronk, Ulrike Mende

PLoS One· February 2023

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Beyond pharmaceuticals: Fit-for-purpose new approach methodologies for environmental cardiotoxicity testing.
Mark C Daley, Ulrike Mende, Bum-Rak Choi, Patrick D McMullen, Kareen L K Coulombe

ALTEX· January 2023

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