Publications by authors named "Patrick D McMullen"

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Network Analysis to Define Pediatric Acute Care Regions in Wisconsin.
Kenneth A Michelson, Katherine E Remick, Emily M Bucholz, Patrick D McMullen, Naveen Singamsetty

Health Serv Res· December 2025

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Out-of-State Acute Care Use Among Pediatric Medicaid Enrollees.
Kenneth A Michelson, Naveen Singamsetty, Andrew D Skol, Katherine E Remick, Emily M Bucholz, Patrick D McMullen

JAMA Netw Open· October 2025

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Development of an Atlas for US Pediatric Acute Care.
Kenneth A Michelson, Andrew D Skol, John A Graves, Katherine E Remick, Patrick D McMullen

JAMA Pediatr· October 2025

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Integrating gene expression and splicing dynamics across dose-response oxidative modulators.
A Rasim Barutcu, Michael B Black, Raymond Samuel, Scott Slattery, Patrick D McMullen

Front Genet· May 2024

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Beyond pharmaceuticals: Fit-for-purpose new approach methodologies for environmental cardiotoxicity testing.
Mark C Daley, Ulrike Mende, Bum-Rak Choi, Patrick D McMullen, Kareen L K Coulombe

ALTEX· January 2023

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Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.
Amy J Stefanowicz, Leslie Recio, Michael B Black, Tyler Beames, Melvin E Andersen, Patrick D McMullen

Int J Toxicol· January 2023

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NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene.
Marjory Moreau, Jeff Fisher, Melvin E Andersen, Asayah Barnwell, Sage Corzine, Patrick D McMullen

Toxicology· November 2022

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Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods.
Chantel I Nicolas, Matthew W Linakis, Melyssa S Minto, Kamel Mansouri, Rebecca A Clewell, Patrick D McMullen

Front Pharmacol· October 2022

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Biological system considerations for application of toxicogenomics in next-generation risk assessment and predictive toxicology.
Michael B Black, Allysa Stern, Alina Efremenko, Pankajini Mallick, Marjory Moreau, Patrick D McMullen

Toxicol In Vitro· April 2022

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Considerations for Improving Metabolism Predictions for to Extrapolation.
Marjory Moreau, Pankajini Mallick, Marci Smeltz, Saad Haider, Chantel I Nicolas, Patrick D McMullen

Front Toxicol· April 2022

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RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days.
Michael B Black, Melvin E Andersen, Salil N Pendse, Susan J Borghoff, Michael Streicker, Patrick D McMullen

Data Brief· October 2021

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A systematic approach to evaluate plausible modes of actions for mouse lung tumors in mice exposed to 4-methylimidozole.
Susan J Borghoff, Seneca E Fitch, Michael B Black, Patrick D McMullen, Melvin E Andersen

Regul Toxicol Pharmacol· August 2021

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Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates.
Rebecca A Clewell, Jeremy A Leonard, Chantel I Nicolas, Jerry L Campbell, Miyoung Yoon, Patrick D McMullen

Toxicol In Vitro· August 2020

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Developing context appropriate toxicity testing approaches using new alternative methods (NAMs).
Melvin E Andersen, Patrick D McMullen, Martin B Phillips, Miyoung Yoon, Salil N Pendse

ALTEX· May 2020

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Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods.
Patrick D McMullen, Sudin Bhattacharya, Courtney G Woods, Salil N Pendse, Mary T McBride

Toxicol In Vitro· April 2020

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A toxicogenomic approach for the risk assessment of the food contaminant acetamide.
Rance Nault, Bryan Bals, Farzaneh Teymouri, Michael B Black, Melvin E Andersen, Patrick D McMullen

Toxicol Appl Pharmacol· February 2020

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The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.
Tyler Beames, Marjory Moreau, L Avery Roberts, Kamel Mansouri, Saad Haider, Patrick D McMullen

Toxicol Appl Pharmacol· January 2020

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Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures.
Patrick D McMullen, Salil N Pendse, Michael B Black, Kamel Mansouri, Saad Haider

Toxicol In Vitro· August 2019

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Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system.
Barbara A Wetmore, Rebecca A Clewell, Brian Cholewa, Bethany Parks, Salil N Pendse, Patrick D McMullen

Toxicol In Vitro· February 2019

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A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation.
Saad Haider, Michael B Black, Bethany B Parks, Briana Foley, Barbara A Wetmore, Patrick D McMullen

Front Pharmacol· October 2018

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An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis.
Jessica K Hartman, Tyler Beames, Bethany Parks, Daniel Doheny, Gina Song, Patrick D McMullen

Toxicol Appl Pharmacol· September 2018

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Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.
Melvin E Andersen, George Cruzan, Michael B Black, Salil N Pendse, Darol E Dodd, Patrick D McMullen

Regul Toxicol Pharmacol· July 2018

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Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays.
Patrick D McMullen, Melvin E Andersen, Brian Cholewa, Harvey J Clewell, Katherine M Dunnick

Toxicol In Vitro· April 2018

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Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.
Melvin E Andersen, George Cruzan, Michael B Black, Salil N Pendse, Darol Dodd, Patrick D McMullen

Toxicol Appl Pharmacol· November 2017

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Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts.
Michelle M Miller, Patrick D McMullen, Melvin E Andersen, Rebecca A Clewell

Crit Rev Toxicol· August 2017

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