Publications by authors named "Ulla Simanainen"

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Quantitative and qualitative concordance between clinical and nonclinical toxicity data.
Chelsea A Weitekamp, Katie Paul Friedman, Alison H Harrill, Scott Auerbach, Omari Bandele, Ulla Simanainen

Toxicol Sci· August 2025

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Integration of new approach methods for the assessment of data-poor chemicals.
Katie Paul Friedman, Russell S Thomas, John F Wambaugh, Joshua A Harrill, Richard S Judson, Ulla Simanainen

Toxicol Sci· May 2025

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Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology.
Gro H Mathisen, Angela Bearth, Lowenna B Jones, Sebastian Hoffmann, Gunn E Vist, Ulla Simanainen

Arch Toxicol· August 2024

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Controlled dual release of dihydrotestosterone and flutamide from polycaprolactone electrospun scaffolds accelerate burn wound healing.
Huaikai Shi, Kevin H-Y Tsai, Duncan Ma, Xiaosuo Wang, Reena Desai, Ulla Simanainen

FASEB J· May 2022

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The contradictory role of androgens in cutaneous and major burn wound healing.
Huaikai Shi, Kenny Cheer, Ulla Simanainen, Brian Lesmana, Duncan Ma

Burns Trauma· January 2021

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Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice.
Huaikai Shi, Tsun-Ho Lo, Duncan Ma, Brenton Condor, Brian Lesmana, Ulla Simanainen

Int J Mol Sci· August 2020

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An electrospun scaffold loaded with anti-androgen receptor compound for accelerating wound healing.
Cassandra Chong, Yiwei Wang, Peter K M Maitz, Ulla Simanainen, Zhe Li

Burns Trauma· August 2016

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Androgen action in female reproductive physiology.
Kirsty A Walters, Ulla Simanainen, Douglas A Gibson

Curr Opin Endocrinol Diabetes Obes· June 2016

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Androgen actions in mouse wound healing: Minimal in vivo effects of local antiandrogen delivery.
Yiwei Wang, Ulla Simanainen, Kenny Cheer, Francia G Suarez, Yan Ru Gao

Wound Repair Regen· May 2016

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Glandular epithelial AR inactivation enhances PTEN deletion-induced uterine pathology.
Jaesung Peter Choi, Yu Zheng, David J Handelsman, Ulla Simanainen

Endocr Relat Cancer· May 2016

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A simple, accurate and universal method for quantification of PCR.
Nicky Boulter, Francia Garces Suarez, Stephen Schibeci, Trevor Sunderland, Ornella Tolhurst, Ulla Simanainen

BMC Biotechnol· March 2016

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In utero/lactational and adult exposures to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) show differential effects on craniofacial development and growth in rats.
Sabrina B Sholts, Merja Korkalainen, Ulla Simanainen, Hanna M Miettinen, Helen Håkansson

Toxicology· November 2015

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Development and Characterization of Uterine Glandular Epithelium Specific Androgen Receptor Knockout Mouse Model.
Jaesung Peter Choi, Yu Zheng, Katherine A Skulte, David J Handelsman, Ulla Simanainen

Biol Reprod· November 2015

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Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer.
Jaesung Peter Choi, Reena Desai, Yu Zheng, Mu Yao, Qihan Dong, Ulla Simanainen

Endocr Relat Cancer· October 2015

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Macronutrient balance, reproductive function, and lifespan in aging mice.
Samantha M Solon-Biet, Kirsty A Walters, Ulla K Simanainen, Aisling C McMahon, Kari Ruohonen

Proc Natl Acad Sci U S A· March 2015

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Androgen receptor actions modify skin structure and chemical carcinogen-induced skin cancer susceptibility in mice.
Ulla Simanainen, Tegan Ryan, Desmond Li, Francia Garces Suarez, Yan Ru Gao

Horm Cancer· February 2015

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Androgen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female mice.
Yan Ru Ellen Gao, Kirsty A Walters, Reena Desai, Hong Zhou, David J Handelsman, Ulla Simanainen

Endocrinology· December 2014

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The role of androgens in experimental rodent mammary carcinogenesis.
Jaesung Choi, Basil Psarommatis, Yan Ru Gao, Yu Zheng, David J Handelsman, Ulla Simanainen

Breast Cancer Res· November 2014

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Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A₂α via AKT in prostate cancer cells.
Soma Vignarajan, Chanlu Xie, Mu Yao, Yuting Sun, Ulla Simanainen

Oncotarget· August 2014

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Glucocorticoid receptor in prostate epithelia is not required for corticosteroid-induced epithelial hyperproliferation in the mouse prostate.
Bin Zhao, Jaesung Peter Choi, Maria Jaehne, Yan Ru Ellen Gao, Reena Desai, Ulla Simanainen

Prostate· July 2014

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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) increases bilirubin formation but hampers quantitative hepatic conversion of biliverdin to bilirubin in rats with wild-type AH receptor.
Marjo Niittynen, Ulla Simanainen, Raimo Pohjanvirta, Satu Sankari, Jouni T Tuomisto

Basic Clin Pharmacol Toxicol· June 2014

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Evidence for increased tissue androgen sensitivity in neurturin knockout mice.
Ulla Simanainen, Yan Ru Ellen Gao, Reena Desai, Mark Jimenez, Jennifer Spaliviero

J Endocrinol· September 2013

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Prostate epithelial AR inactivation leads to increased intraprostatic androgen synthesis.
Keely M McNamara, Yasuhiro Nakamura, Hironobu Sasano, David J Handelsman, Ulla Simanainen

Prostate· February 2013

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Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.
Ulla Simanainen, Yan Ru Gao, Kirsty A Walters, Geoff Watson, Reena Desai

Horm Cancer· June 2012

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Targeted loss of androgen receptor signaling in murine granulosa cells of preantral and antral follicles causes female subfertility.
Kirsty A Walters, Linda J Middleton, Shai R Joseph, Rasmani Hazra, Mark Jimenez, Ulla Simanainen

Biol Reprod· June 2012

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