Publications by authors named "Umashankar Das"

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Does Ortho-Substitution Enhance Cytotoxic Potencies in a Series of 3,5-Bis(benzylidene)-4-piperidones?
Subhas S Karki, Umashankar Das, Jan Balzarini, Erik De Clercq, Hiroshi Sakagami

Medicines (Basel)· October 2024

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Dimeric 3,5-Bis(benzylidene)-4-piperidones: Tumor-Selective Cytotoxicity and Structure-Activity Relationships.
Swagatika Das, Praveen K Roayapalley, Hiroshi Sakagami, Naoki Umemura, Dennis K J Gorecki, Umashankar Das

Medicines (Basel)· January 2024

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Anticonvulsant Properties of 1-Diethylamino-3-phenylprop-2-en-1-one.
Swagatika Das, Praveen K Roayapalley, Sarvesh C Vashishtha, Umashankar Das, Jonathan R Dimmock

Medicines (Basel)· September 2023

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Cytotoxic derivatives of dichloroacetic acid and some metal complexes.
Mohammad Hossain, Shayne Roth, Jonathan R Dimmock, Umashankar Das

Arch Pharm (Weinheim)· November 2022

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Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.
Risa Mia Swain, Lisett Contreras, Armando Varela-Ramirez, Mohammad Hossain, Umashankar Das

Invest New Drugs· October 2022

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Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity.
Aruna Chhikara, Praveen K Roayapalley, Hiroshi Sakagami, Shigeru Amano, Keitaro Satoh, Umashankar Das, Swagatika Das

Molecules· October 2022

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1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)- 4-Piperidone Hydrochloride and Related Compounds: Potent Cytotoxins Demonstrate Greater Toxicity to Neoplasms than Non- Malignant Cells.
Praveen K Roayapalley, Jonathan R Dimmock, Hiroshi Sakagami, Noriyki Okudaira, Rajendra K Sharma, Umashankar Das

Med Chem· July 2022

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Dichloroacetyl Amides of 3,5-Bis(benzylidene)-4-piperidones Displaying Greater Toxicity to Neoplasms than to Non-Malignant Cells.
Mohammad Hossain, Praveen K Roayapalley, Hiroshi Sakagami, Keitaro Satoh, Kenjiro Bandow, Umashankar Das

Medicines (Basel)· June 2022

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Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms.
Lisett Contreras, Stephanie Medina, Austre Y Schiaffino Bustamante, Edgar A Borrego, Carlos A Valenzuela, Umashankar Das

Pharmacol Rep· February 2022

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Cytotoxic Tumour-Selective 1,5-Diaryl-3-Oxo-1,4-Pentadienes Mounted on a Piperidine Ring.
Praveen K Roayapalley, Hiroshi Sakagami, Keitaro Satoh, Shigeru Amano, Kenjiro Bandow, Umashankar Das

Medicines (Basel)· December 2021

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Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts.
Praveen K Roayapalley, Jonathan R Dimmock, Lisett Contreras, Karol S Balderrama, Renato J Aguilera, Umashankar Das

Molecules· November 2021

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Clinical Symptoms and Types of Samples Are Critical Factors for the Molecular Diagnosis of Symptomatic COVID-19 Patients: A Systematic Literature Review.
Milad Zandi, Abbas Farahani, Armin Zakeri, Sara Akhavan Rezayat, Ramin Mohammadi, Umashankar Das

Int J Microbiol· September 2021

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Discovery and Investigation of 1-[4-(2-Aminoethoxy)Phenylcarbonyl]- 3,5-Bis-(Benzylidene)-4-Piperidones as Candidate Antineoplastic Agents: Our Last 15 Years Study.
Mohammad Hossain, Carlos E Enci, Jonathan R Dimmock, Umashankar Das

Curr Med Chem· June 2021

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Design, Syntheses, and Bioevaluations of Some Novel -Acryloylbenzohydrazides as Chemostimulants and Cytotoxic Agents.
Kinjal Lakhani, Edgar A Borrego, Karla G Cano, Jonathan R Dimmock, Renato J Aguilera, Swagatika Das, Umashankar Das

Medicines (Basel)· June 2021

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Roles of Histone Deacetylases and Inhibitors in Anticancer Therapy.
Flávia Alves Verza, Umashankar Das, Ana Lúcia Fachin, Jonathan R Dimmock, Mozart Marins

Cancers (Basel)· June 2020

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Novel hybrid molecules of 3,5-bis(benzylidene)-4-piperidones and dichloroacetic acid which demonstrate potent tumour-selective cytotoxicity.
Mohammad Hossain, Swagatika Das, Umashankar Das, Alireza Doroudi, Jianfeng Zhu

Bioorg Med Chem Lett· February 2020

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Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins.
Mohammad Hossain, Umashankar Das, Jonathan R Dimmock

Eur J Med Chem· December 2019

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Novel Conjugated Unsaturated Ketones with Submicromolar Potencies Towards some Leukemic and Colon Cancer Cells.
Swagatika Das, H Inci Gul, Umashankar Das, Jan Balzarini, Stephen G Dimmock

Med Chem· June 2019

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Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones.
Lisett Contreras, Ruben I Calderon, Armando Varela-Ramirez, Hong-Yu Zhang, Yuan Quan, Umashankar Das

Cell Oncol (Dordr)· December 2018

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3,5-Bis(3-dimethylaminomethyl-4-hydroxybenzylidene)-4-piperidone and related compounds induce glutathione oxidation and mitochondria-mediated cell death in HCT-116 colon cancer cells.
Eshwari Addala, Hossein Rafiei, Swagatika Das, Brian Bandy, Umashankar Das

Bioorg Med Chem Lett· August 2017

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6-Benzylidene-2-[4-(pyridin-3-ylcarboxy)benzylidene]cyclohexanones: A novel cluster of tumour-selective cytotoxins.
Atulya K Panda, Umashankar Das, Naoki Umemura, Hiroshi Sakagami, Masami Kawase

Bioorg Med Chem Lett· April 2017

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Investigations on Binding Pattern of Kinase Inhibitors with PPAR: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies.
Mohit Mazumder, Prija Ponnan, Umashankar Das, Samudrala Gourinath, Haseeb Ahmad Khan

PPAR Res· February 2017

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In-situ chemical oxidation: Principle and applications of peroxide and persulfate treatments in wastewater systems.
Parmila Devi, Umashankar Das, Ajay K Dalai

Sci Total Environ· November 2016

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Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models.
Najmeh Edraki, Umashankar Das, Bahram Hemateenejad, Jonathan R Dimmock, Ramin Miri

Iran J Pharm Res· September 2016

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Tumor-selective cytotoxicity of a novel pentadiene analogue on human leukemia/ lymphoma cells.
Yahaira Santiago-Vázquez, Umashankar Das, Armando Varela-Ramirez, Sarah T Baca, Yoshira Ayala-Marin, Swagatika Das

Clin Cancer Drugs· January 2016

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