Publications by authors named "Unbin Chae"

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Precise progerin targeting using RfxCas13d: A therapeutic avenue for Hutchinson-Gilford progeria syndrome.
Unbin Chae, Hae-Jun Yang, Hanseop Kim, Seung Hwan Lee, Dong Gil Lee

Mol Ther· September 2025

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Designing an apoptosis reporter by mutagenesis-based insertion of caspase-3 cleavage motif into green fluorescence protein.
Dong Gil Lee, Hae-Jun Yang, Unbin Chae, Hong Jun Lee, Dong-Seok Lee

J Adv Res· June 2025

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Peroxiredoxin-6 regulates p38-mediated epithelial-mesenchymal transition in HCT116 colon cancer cells.
Unbin Chae, Bokyung Kim, HanSeop Kim, Young-Ho Park, Seung Hwan Lee

J Biol Res (Thessalon)· November 2021

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Establishment and Characterization of Immortalized Miniature Pig Pancreatic Cell Lines Expressing Oncogenic K-Ras.
Hae-Jun Yang, Bong-Seok Song, Bo-Woong Sim, Yena Jung, Unbin Chae

Int J Mol Sci· November 2020

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Parkin in early stage LPS-stimulated BV-2 cells regulates pro-inflammatory response and mitochondrial quality via mitophagy.
Hye Keun Yun, Junghyung Park, UnBin Chae, Hyun-Shik Lee, Jae-Won Huh

J Neuroimmunol· November 2019

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Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
Unbin Chae, Jeen-Woo Park, Sang-Rae Lee, Hong Jun Lee, Hyun-Shik Lee

Aging (Albany NY)· September 2019

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Drp1-dependent mitochondrial fission regulates p62-mediated autophagy in LPS-induced activated microglial cells.
Unbin Chae, Han Seop Kim, Hyun-Shik Lee, Sang-Rae Lee, Dong-Seok Lee

Biosci Biotechnol Biochem· March 2019

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A negative feedback loop between XBP1 and Fbw7 regulates cancer development.
Unbin Chae, Heejin Lee, Bokyung Kim, Haiyoung Jung, Byeong Mo Kim

Oncogenesis· February 2019

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IDH2 Deficiency in Microglia Decreases the Pro-inflammatory Response via the ERK and NF-κB Pathways.
Unbin Chae, Han Seop Kim, Kyung-Min Kim, Heejin Lee, Hyun-Shik Lee

Inflammation· October 2018

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Oleuropein isolated from Fraxinus rhynchophylla inhibits glutamate-induced neuronal cell death by attenuating mitochondrial dysfunction.
Mi Hye Kim, Ju-Sik Min, Joon Yeop Lee, Unbin Chae, Eun-Ju Yang

Nutr Neurosci· September 2018

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Peroxiredoxin 2 mediates insulin sensitivity of skeletal muscles through regulation of protein tyrosine phosphatase oxidation.
Jung-Hak Kim, Sun-Ji Park, Unbin Chae, Joongbae Seong, Hyun-Shik Lee

Int J Biochem Cell Biol· June 2018

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Chrysophanol Suppressed Glutamate-Induced Hippocampal Neuronal Cell Death via Regulation of Dynamin-Related Protein 1-Dependent Mitochondrial Fission.
Unbin Chae, Ju-Sik Min, Hyun Hee Leem, Hyun-Shik Lee, Hong Jun Lee

Pharmacology· April 2018

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Peroxiredoxin 5 Decreases Beta-Amyloid-Mediated Cyclin-Dependent Kinase 5 Activation Through Regulation of Ca-Mediated Calpain Activation.
Junghyung Park, Bokyung Kim, Unbin Chae, Dong Gil Lee, Min Kyoung Kam

Antioxid Redox Signal· October 2017

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Chrysophanol suppresses pro-inflammatory response in microglia via regulation of Drp1-dependent mitochondrial fission.
Unbin Chae, Ju-Sik Min, Hanna Lee, Kyung-Sik Song, Hyun-Shik Lee

Immunopharmacol Immunotoxicol· October 2017

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Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission.
Junghyung Park, Ju-Sik Min, Unbin Chae, Joon Yeop Lee, Kyung-Sik Song

J Neuroimmunol· May 2017

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Peroxiredoxin 5 (Prx5) decreases LPS-induced microglial activation through regulation of Ca/calcineurin-Drp1-dependent mitochondrial fission.
Junghyung Park, Hoonsung Choi, Bokyung Kim, Unbin Chae, Dong Gil Lee

Free Radic Biol Med· October 2016

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Critical role of XBP1 in cancer signalling is regulated by PIN1.
Unbin Chae, Sun-Ji Park, Bokyung Kim, Shou Wei, Ju-Sik Min

Biochem J· September 2016

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Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways.
Junghyung Park, Ju-Sik Min, Bokyung Kim, Un-Bin Chae, Jong Won Yun

Neurosci Lett· January 2015

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