Publications by authors named "Ursula Grohmann"

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Ustekinumab Tissue and Serum Levels in Patients With Crohn's Disease Are Closely Correlated Though Not Consistently Associated With Objective Response After Induction.
Elisa Proietti, Renske W M Pauwels, Christien J van der Woude, Michael Doukas, Lindsey Oudijk, Ursula Grohmann

Inflamm Bowel Dis· July 2023

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Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme.
Maria Teresa Pallotta, Sofia Rossini, Chiara Suvieri, Alice Coletti, Ciriana Orabona, Ursula Grohmann

FEBS J· October 2022

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Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls.
Andrea Mammoli, Elisa Bianconi, Luana Ruta, Alessandra Riccio, Carlo Bigiotti, Ursula Grohmann

Int J Mol Sci· April 2022

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Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity.
Giada Mondanelli, Elisa Albini, Elena Orecchini, Maria Teresa Pallotta, Maria Laura Belladonna, Ursula Grohmann

Front Immunol· December 2021

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Vedolizumab Tissue Concentration Correlates to Mucosal Inflammation and Objective Treatment Response in Inflammatory Bowel Disease.
Renske W M Pauwels, Elisa Proietti, Christien J van der Woude, Lindsey Oudijk, Marie-Rose B S Crombag, Ursula Grohmann

Inflamm Bowel Dis· October 2021

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Current Challenges for IDO2 as Target in Cancer Immunotherapy.
Giada Mondanelli, Martina Mandarano, Maria Laura Belladonna, Chiara Suvieri, Cristina Pelliccia, Ursula Grohmann

Front Immunol· October 2021

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3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.
Cristina C Clement, Angelo D'Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Ursula Grohmann

Nat Commun· July 2021

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Editorial overview: Indoles: very busy (and not indolent) molecules at work in immune regulation.
Ursula Grohmann

Curr Opin Immunol· June 2021

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Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation.
Eleonora Panfili, Giada Mondanelli, Ciriana Orabona, Maria L Belladonna, Marco Gargaro, Ursula Grohmann

Hum Mol Genet· April 2021

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Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine.
Sonia Bianchini, Ciriana Orabona, Barbara Camilloni, Maria Giulia Berioli, Alberto Argentiero, Ursula Grohmann

Hum Vaccin Immunother· March 2021

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The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions.
Marco Gargaro, Giulia Scalisi, Giorgia Manni, Giada Mondanelli, Ursula Grohmann

Int J Mol Sci· January 2021

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A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function.
Giada Mondanelli, Valeria Di Battista, Fabrizia Pellanera, Andrea Mammoli, Antonio Macchiarulo, Ursula Grohmann

J Autoimmun· December 2020

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Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Alberta Iacono, Andrea Pompa, Francesca De Marchis, Eleonora Panfili, Francesco A Greco, Ursula Grohmann

EMBO Rep· December 2020

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Polyamines and Kynurenines at the Intersection of Immune Modulation.
Elisa Proietti, Sofia Rossini, Ursula Grohmann, Giada Mondanelli

Trends Immunol· November 2020

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Immunoregulatory Interplay Between Arginine and Tryptophan Metabolism in Health and Disease.
Giada Mondanelli, Alberta Iacono, Massimo Allegrucci, Paolo Puccetti, Ursula Grohmann

Front Immunol· October 2020

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Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.
Marco Gargaro, Carmine Vacca, Serena Massari, Giulia Scalisi, Giorgia Manni, Ursula Grohmann

Front Immunol· October 2020

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Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Erik Ladomersky, Lijie Zhai, Kristen L Lauing, April Bell, Jiahui Xu, Ursula Grohmann

Clin Cancer Res· October 2020

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Amino Acid Metabolism in Rheumatoid Arthritis: Friend or Foe?
Eleonora Panfili, Roberto Gerli, Ursula Grohmann, Maria Teresa Pallotta

Biomolecules· September 2020

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Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity.
Giada Mondanelli, Agostinho Carvalho, Paolo Puccetti, Ursula Grohmann, Claudia Volpi

Proc Natl Acad Sci U S A· September 2020

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Exemplifying complexity of immune suppression by a "canonical" speech: A glimpse into TNFRSF-activated signaling pathways in Treg cells.
Emira Ayroldi, Ursula Grohmann

Eur J Immunol· July 2020

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New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures.
Andrea Mammoli, Alice Coletti, Marco Ballarotto, Alessandra Riccio, Andrea Carotti, Ursula Grohmann

ChemMedChem· May 2020

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Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Giada Mondanelli, Alice Coletti, Francesco Antonio Greco, Maria Teresa Pallotta, Ciriana Orabona, Ursula Grohmann

Proc Natl Acad Sci U S A· February 2020

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Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1.
Francesco A Greco, Elisa Albini, Alice Coletti, Daniela Dolciami, Andrea Carotti, Ursula Grohmann

ChemMedChem· December 2019

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Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis.
Claudia Volpi, Ciriana Orabona, Antonio Macchiarulo, Roberta Bianchi, Paolo Puccetti, Ursula Grohmann

Expert Opin Drug Discov· November 2019

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Wolfram syndrome, a rare neurodegenerative disease: from pathogenesis to future treatment perspectives.
Maria Teresa Pallotta, Giorgia Tascini, Roberta Crispoldi, Ciriana Orabona, Giada Mondanelli, Ursula Grohmann

J Transl Med· July 2019

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