Publications by authors named "Ursula Matte"

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Recent Advances in Nose-to-Brain Gene Delivery for Central Nervous System Disorders.
Flávia Nathiely Silveira Fachel, Angélica Salatino-Oliveira, Willian da Silva Carniel, Rafaela Zimmermann, Ursula Matte

Pharmaceutics· September 2025

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Genetic Variants Influence the Severity of Oral Mucositis in Pediatric Osteosarcoma Patients.
Renata de Almeida Zieger, Mariana Rodrigues Botton, Marina Curra, Amanda de Farias Gabriel, Stefanie Thieme, Ursula da Silveira Matte

Oral Dis· June 2025

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Newborn Intravenous Injection of Liposomal CRISPR/Cas9 Complex Has No Incidence of Off-Targets or Tumors in Mice.
Vinícius Monteagudo, Larissa Cristina Barbosa Flores, Melaine Lopes, Flavia Nathiely Silveira Fachel, Giselle Martins, Ursula Matte

Pharmaceutics· May 2025

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Laronidase-loaded liposomes reach the brain and other hard-to-treat organs after noninvasive nasal administration.
Roselena Silvestri Schuh, Eduarda Piovesan Franceschi, Bruna Brazeiro Brum, Flávia Nathiely Silveira Fachel, Édina Poletto, Ursula Matte

Int J Pharm· July 2024

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Regulatory Framework, Challenges, and Initial Strategic Planning for Advanced Therapy Products (PTAs) Development in Brazil.
Flávia Nathiely Silveira Fachel, Roselena Silvestri Schuh, Patrícia Bencke Grudzinski, Helder Ferreira Teixeira, Guilherme Baldo, Ursula Matte

Ther Innov Regul Sci· January 2024

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Broken silence: 22,841 predicted deleterious synonymous variants identified in the human exome through computational analysis.
Ana Carolina Mello, Delva Leao, Luis Dias, Felipe Colombelli, Mariana Recamonde-Mendoza, Ursula Matte

Genet Mol Biol· January 2024

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Identification of adverse drug reactions that may be related to pharmacogenetics in a public hospital in the South of Brazil.
Amanda C Camargo, Ursula Matte, Mariana R Botton

Expert Opin Drug Saf· November 2023

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CRISPR/Cas patents and health-related publications in South America.
Lariane Frâncio, Martiela V DE Freitas, Ursula Matte

An Acad Bras Cienc· June 2023

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Analysis of the interval between submission and publication in genetics journals.
Rafael Leal Zimmer, Aline Castello Branco Mancuso, Ursula Matte, Patricia Ashton-Prolla

PLoS One· May 2023

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Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses.
Flávia Nathiely Silveira Fachel, Lariane Frâncio, Édina Poletto, Roselena Silvestri Schuh, Helder Ferreira Teixeira, Ursula Matte

Adv Drug Deliv Rev· December 2022

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Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis.
Gerda Cristal Villalba Silva, Thiago Steindorff, Roselena Silvestri Schuh, Natalia Cardoso Flores, Ursula Matte

Life (Basel)· December 2022

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Protection is not always a good thing: The immune system's impact on gene therapy.
Martiela Vaz de Freitas, Lariane Frâncio, Laura Haleva, Ursula da Silveira Matte

Genet Mol Biol· July 2022

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Sales of "COVID kit" drugs and adverse drug reactions reported by the Brazilian Health Regulatory Agency.
Marina Hentschke-Lopes, Mariana R Botton, Pâmella Borges, Martiela Freitas, Aline Castello Branco Mancuso, Ursula Matte

Cad Saude Publica· July 2022

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Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system.
Luisa Natalia Pimentel Vera, Roselena Silvestri Schuh, Flavia Nathielly Silveira Fachel, Edina Poletto, Eduarda Piovesan, Ursula Matte

J Gene Med· April 2022

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Frequency of DPYD gene variants and phenotype inference in a Southern Brazilian population.
Mariana Rodrigues Botton, Marina Hentschke-Lopes, Ursula Matte

Ann Hum Genet· March 2022

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In silico analysis of potential off-target sites to gene editing for Mucopolysaccharidosis type I using the CRISPR/Cas9 system: Implications for population-specific treatments.
Paola Carneiro, Martiela Vaz de Freitas, Ursula Matte

PLoS One· February 2022

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Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes.
Michelle Fraga, Roselena Silvestri Schuh, Édina Poletto, Talita Giacomet de Carvalho, Raqueli Teresinha França, Ursula Matte

Curr Gene Ther· January 2022

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Genome editing in mucopolysaccharidoses and mucolipidoses.
Hallana Souza Santos, Edina Poletto, Roselena Schuh, Ursula Matte, Guilherme Baldo

Prog Mol Biol Transl Sci· November 2021

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Which Is the Best Program for the Missense Variations in IDUA Gene? A Comparison of 33 Programs Plus a Conservation Score and Evaluation of 586 Missense Variants.
Pâmella Borges, Gabriela Pasqualim, Ursula Matte

Front Mol Biosci· October 2021

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Disruption of morphogenic and growth pathways in lysosomal storage diseases.
Thiago Corrêa, Bruno C Feltes, Roberto Giugliani, Ursula Matte

WIREs Mech Dis· September 2021

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MPSBase: Comprehensive repository of differentially expressed genes for mucopolysaccharidoses.
Luís Dias Ferreira Soares, Gerda Cristal Villalba Silva, Francyne Kubaski, Roberto Giugliani, Ursula Matte

Mol Genet Metab· August 2021

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Biodistribution of Transplanted Hematopoietic Precursor Cells Injected Through Different Administration Routes in Newborn Mice.
Edina Poletto, Camila Vieira Pinheiro, Roselena Silvestri Schuh, Daniela Campagnol, Marta Cioato, Ursula Matte

Hum Gene Ther· May 2021

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Fantastic databases and where to find them: Web applications for researchers in a rush.
Gerda Cristal Villalba, Ursula Matte

Genet Mol Biol· April 2021

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Variants p.Pro2063Ser and p.Arg324* co-segregate in type 3 von Willebrand disease patients from Southern Brazil.
Ana Paula Ornaghi, Mariana Rost Meireles, Mariana Rodrigues Botton, Francisco Mauro Salzano, Eliane Bandinelli, Ursula Matte

Haemophilia· March 2021

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Gene panel for the diagnosis of epidermolysis bullosa: proposal for a viable and efficient approach.
Luiza Monteavaro Mariath, Ana Elisa Kiszewski, Jeanine Aparecida Frantz, Marina Siebert, Ursula Matte

An Bras Dermatol· March 2021

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