Publications by authors named "Utkarsh Doshi"

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Generalizable Multimodal Retinal Image Registration via Label-free Vessel Segmentation.
Utkarsh Doshi, Elli Davis, Mayss Al-Sheikh, José-Alain Sahel, Jay Chhablani

Biomed Signal Process Control· March 2026

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Benchmarking diffusion models against state-of-the-art architectures for OCT fluid biomarker segmentation.
Katherine Du, Utkarsh Doshi, Benjamin DiCenzo, Jessica Jiang, Ethan Wu

PLoS One· October 2025

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In vitro evaluation of the metabolic stability of nine fragrance chemicals in trout and human hepatocytes.
John Weeks, Albert P Li, Utkarsh Doshi, Karla Johanning, Patrick D Guiney

J Appl Toxicol· October 2020

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A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.
Anita R Iskandar, Filippo Zanetti, Athanasios Kondylis, Florian Martin, Patrice Leroy, Utkarsh Doshi

Intern Emerg Med· September 2019

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Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions.
Susan Wong, Utkarsh Doshi, Peter Vuong, Ning Liu, Suzanne Tay

Drug Metab Lett· January 2019

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Prediction of the Pharmacokinetics of Pravastatin as an OATP Substrate Using Plateable Human Hepatocytes With Human Plasma Data and PBPK Modeling.
Jialin Mao, Utkarsh Doshi, Matthew Wright, Cornelis E C A Hop, Albert P Li

CPT Pharmacometrics Syst Pharmacol· April 2018

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Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors.
Ming-Chih David Ho, Nicholas Ring, Kirsten Amaral, Utkarsh Doshi, Albert P Li

Drug Metab Dispos· June 2017

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A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds.
Chi-Chi Peng, Utkarsh Doshi, Chandra Prakash, Albert P Li

Drug Metab Lett· December 2016

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Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells.
Zhen Ren, Si Chen, Jie Zhang, Utkarsh Doshi, Albert P Li

Toxicol Sci· December 2016

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Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles.
Jie Zhang, Utkarsh Doshi, Ayako Suzuki, Ching-Wei Chang, Jürgen Borlak

Chem Biol Interact· August 2016

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In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
Doshi Utkarsh, Carol Loretz, Albert P Li

Chem Biol Interact· August 2016

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Culture duration-, donor-, and medium-dependent changes in OATP1B3-mediated telmisartan uptake in human hepatocytes.
Qing Zhu, Haiyan Xia, Cindy Q Xia, Qian Yang, Utkarsh Doshi

Drug Metab Lett· July 2014

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Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6: implications for experimental design for the evaluation of downregulatory effects of biotherapeutics.
Qian Yang, Utkarsh Doshi, Nicole Li, Albert P Li

Curr Drug Metab· September 2012

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Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction.
Utkarsh Doshi, Albert P Li

J Biomol Screen· September 2011

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Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4.
Albert P Li, Utkarsh Doshi

Drug Metab Lett· August 2011

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Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones.
Hardik J Patel, Joe Sarra, Francesco Caruso, Miriam Rossi, Utkarsh Doshi

Bioorg Med Chem Lett· September 2006

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