Publications by authors named "Valen Z Yu"

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Characterizing chromosome instability reveals its association with lipid-associated macrophages and clonal evolution of lymph node metastasis in esophageal squamous cell carcinoma.
Wei Dai, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Zhaozheng Hou, Larry Ka-Yue Chow, Michael King Yung Chung, Ian Yu Hong Wong

Cancer Lett· September 2025

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Cell-associated galectin 9 interacts with cytotoxic T cells confers resistance to tumor killing in nasopharyngeal carcinoma through autophagy activation.
Ngar-Woon Kam, Cho Yiu Lau, Jeffrey Yan Ho Lau, Xin Dai, Yusi Liang, Michael King Yung Chung, Valen Zhuoyou Yu

Cell Mol Immunol· March 2025

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ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma.
Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-Chad Lung, George Zhaozheng Hou, Carissa Wing-Yan Wong, Larry Ka-Yue Chow, Michael King-Yung Chung, Ian Yu-Hong Wong

Cancer Lett· July 2024

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Multigene Profiling of Circulating Tumor Cells in Esophageal Squamous Cell Carcinoma Identifies Prognostic Cancer Driver Genes Associated with Epithelial-Mesenchymal-Transition Progression and Chemoresistance.
Zhen Tan, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Ka-On Lam, Dora Lai-Wan Kwong, Ian Yu-Hong Wong

Cancers (Basel)· November 2023

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Differentiation-related zinc finger protein 750 suppresses cell growth in esophageal squamous cell carcinoma.
Sheyne Sta Ana Choi, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Lvwen Ning, Maria Li Lung

Oncol Lett· July 2021

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Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma.
Jian Li, Josephine Mun-Yee Ko, Wei Dai, Valen Zhuoyou Yu, Hoi Yan Ng

Cancers (Basel)· June 2021

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Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma.
Valen Z Yu, Joseph C Y Ip, Josephine M Y Ko, Lihua Tao, Alfred K Lam

Methods Mol Biol· March 2021

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Gain-of-function hot spot mutant p53 regulation of integrin/FAK/ERK signaling in esophageal squamous cell carcinoma.
Valen Zhuoyou Yu, Shan Shan So, Maria Li Lung

Transl Oncol· January 2021

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Clinical Outcome-Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma.
Wei Dai, Dittman Lai-Shun Chung, Larry Ka-Yue Chow, Valen Zhuoyou Yu, Lisa Chan Lei

Clin Cancer Res· December 2020

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Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci.
Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan

Commun Biol· December 2020

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FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression.
Lisa Chan Lei, Valen Zhuoyou Yu, Josephine Mun Yee Ko, Lvwen Ning, Maria Li Lung

Cancers (Basel)· September 2020

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Cylindromatosis Lysine 63 Deubiquitinase (CYLD) Regulates NF-kB Signaling Pathway and Modulates Fibroblast and Endothelial Cells Recruitment in Nasopharyngeal Carcinoma.
Mingdan Deng, Wei Dai, Valen Zhuoyou Yu, Lihua Tao, Maria Li Lung

Cancers (Basel)· July 2020

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Endoplasmic reticulum-localized ECM1b suppresses tumor growth and regulates MYC and MTORC1 through modulating MTORC2 activation in esophageal squamous cell carcinoma.
Valen Zhuoyou Yu, Josephine Mun Yee Ko, Lvwen Ning, Wei Dai, Simon Law

Cancer Lett· October 2019

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Chemotherapeutic Treatments Increase PD-L1 Expression in Esophageal Squamous Cell Carcinoma through EGFR/ERK Activation.
Hoi Yan Ng, Jian Li, Lihua Tao, Alfred King-Yin Lam, Kwok Wah Chan, Valen Zhuoyou Yu

Transl Oncol· December 2018

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Corrigendum to "A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma".
Joseph Chok Yan Ip, Josephine Mun Yee Ko, Valen Zhuoyou Yu, Kwok Wah Chan, Alfred K Lam

Biomed Res Int· July 2016

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DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Hoi Yan Ng, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Joseph Chok Yan Ip, Wei Dai

Int J Cancer· June 2016

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A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma.
Joseph Chok Yan Ip, Josephine Mun Yee Ko, Valen Zhuoyou Yu, Kwok Wah Chan, Alfred K Lam

Biomed Res Int· December 2015

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Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells.
Valen Zhuoyou Yu, Victor Chun-Lam Wong, Wei Dai, Josephine Mun-Yee Ko, Alfred King-Yin Lam, Yuen Piu Chan, Nikki Pui-Yue Lee

Gastroenterology· December 2015

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