Publications by authors named "Valentin Vlassov"

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Biological Performance and Molecular Mechanisms of Mesyl MicroRNA-Targeted Oligonucleotides in Colorectal Cancer Cells.
Svetlana K Miroshnichenko, Olga A Patutina, Andrey V Markov, Maxim S Kupryushkin, Valentin V Vlassov

Int J Mol Sci· December 2025

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Reversing the Irreversible: miRNA-Targeting Mesyl Phosphoramidate Oligonucleotides Restore Sensitivity to Cisplatin and Doxorubicin of KB-8-5 Epidermoid Carcinoma Cells.
Svetlana Miroshnichenko, Rabia Demirel, Arseny Moralev, Olga Almieva, Andrey Markov, Valentin Vlassov

Biomedicines· December 2025

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Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA.
Anastasiya Oshchepkova, Ivan Chernikov, Svetlana Miroshnichenko, Olga Patutina, Oleg Markov, Valentin Vlassov

Front Bioeng Biotechnol· October 2024

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Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models.
Daria Chiglintseva, David J Clarke, Aleksandra Sen'kova, Thomas Heyman, Svetlana Miroshnichenko, Valentin Vlassov

Biomaterials· September 2024

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Cholesterol-Modified Anti-Il6 siRNA Reduces the Severity of Acute Lung Injury in Mice.
Ivan V Chernikov, Irina K Bachkova, Aleksandra V Sen'kova, Mariya I Meschaninova, Innokenty A Savin, Valentin V Vlassov

Cells· April 2024

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Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification.
Ivan V Chernikov, Ul'yana A Ponomareva, Mariya I Meschaninova, Irina K Bachkova, Valentin V Vlassov

Molecules· February 2024

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Cholesterol-Conjugated Supramolecular Multimeric siRNAs: Effect of siRNA Length on Accumulation and Silencing and .
Ivan V Chernikov, Ul'yana A Ponomareva, Mariya I Meschaninova, Irina K Bachkova, Anna A Teterina, Valentin V Vlassov

Nucleic Acid Ther· December 2023

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Intron Editing Reveals -Dependent Maturation of the Small Nucleolar RNA Host Gene in Human Cells.
Anastasiya Matveeva, Dmitry Vinogradov, Evgenii Zhuravlev, Dmitriy Semenov, Valentin Vlassov

Int J Mol Sci· December 2023

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Extracellular Vesicles for Therapeutic Nucleic Acid Delivery: Loading Strategies and Challenges.
Anastasiya Oshchepkova, Marina Zenkova, Valentin Vlassov

Int J Mol Sci· April 2023

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siRNA-Mediated Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury.
Ivan V Chernikov, Yaroslav Yu Staroseletz, Irina S Tatarnikova, Aleksandra V Sen'kova, Innokenty A Savin, Valentin V Vlassov

Int J Mol Sci· January 2023

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Tribute to Sidney Altman.
Venkat Gopalan, Timothy Nilsen, Venkat Gopalan, Ann M Altman, Benjamin C Stark, Valentin Vlassov

RNA· November 2022

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Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy.
Svetlana Gaponova, Olga Patutina, Aleksandra Sen'kova, Ekaterina Burakova, Innokenty Savin, Valentin Vlassov

Cancers (Basel)· September 2022

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Bulge-Forming miRNases Cleave Oncogenic miRNAs at the Central Loop Region in a Sequence-Specific Manner.
Olga Patutina, Daria Chiglintseva, Bahareh Amirloo, David Clarke, Svetlana Gaponova, Valentin Vlassov

Int J Mol Sci· June 2022

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Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells.
Maxim S Kupryushkin, Anton V Filatov, Nadezhda L Mironova, Olga A Patutina, Ivan V Chernikov, Valentin V Vlassov

Mol Ther Nucleic Acids· March 2022

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Tropism of Extracellular Vesicles and Cell-Derived Nanovesicles to Normal and Cancer Cells: New Perspectives in Tumor-Targeted Nucleic Acid Delivery.
Anastasiya Oshchepkova, Oleg Markov, Evgeniy Evtushenko, Alexander Chernonosov, Elena Kiseleva, Valentin Vlassov

Pharmaceutics· November 2021

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Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy.
Daniil V Gladkikh, Aleksandra V Sen Kova, Ivan V Chernikov, Tatyana O Kabilova, Nelly A Popova, Valentin V Vlassov

Pharmaceutics· August 2021

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Influence of Caudovirales Phages on Humoral Immunity in Mice.
Anton Chechushkov, Yuliya Kozlova, Ivan Baykov, Vera Morozova, Bogdana Kravchuk, Valentin Vlassov

Viruses· June 2021

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The Core of Gut Life: Profile in Patients with Relapsing-Remitting Multiple Sclerosis.
Madina Kozhieva, Natalia Naumova, Tatiana Alikina, Alexey Boyko, Valentin Vlassov

Life (Basel)· January 2021

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Human Gut Microbiome Response to Short-Term -Based Probiotic Treatment.
Natalia Naumova, Tatiana Alikina, Alexey Tupikin, Anna Kalmykova, Galina Soldatova, Valentin Vlassov

Indian J Microbiol· December 2020

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Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency.
Olga A Patutina, Svetlana K Gaponova Miroshnichenko, Aleksandra V Sen'kova, Innokenty A Savin, Daniil V Gladkikh, Valentin V Vlassov

Proc Natl Acad Sci U S A· December 2020

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Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides.
Azad Mamedov, Nadezhda Vorobyeva, Ioanna Filimonova, Maria Zakharova, Ivan Kiselev, Valentin Vlassov

Front Immunol· November 2020

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Immunostimulating RNA Delivered by P1500 PEGylated Cationic Liposomes Limits Influenza Infection in C57Bl/6 Mice.
Elena P Goncharova, Aleksandra V Sen'kova, Innokenty A Savin, Tat'yana O Kabilova, Marina A Zenkova, Valentin V Vlassov

Pharmaceutics· September 2020

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Transport Oligonucleotides-A Novel System for Intracellular Delivery of Antisense Therapeutics.
Oleg V Markov, Anton V Filatov, Maxim S Kupryushkin, Ivan V Chernikov, Olga A Patutina, Valentin V Vlassov

Molecules· August 2020

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Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance.
Olga Patutina, Daria Chiglintseva, Elena Bichenkova, Svetlana Gaponova, Nadezhda Mironova, Valentin Vlassov

Molecules· May 2020

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Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity.
Ivan V Chernikov, Daniil V Gladkikh, Ulyana A Karelina, Mariya I Meschaninova, Alya G Ven'yaminova, Valentin V Vlassov

Molecules· April 2020

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