Publications by authors named "Valer Gotea"

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Identification of RNA binding proteins that mediate a quality control mechanism of splicing.
Maram Arafat, Valer Gotea, Mubarak I Umar, Aya Muharram, Eyal Kamhi

bioRxiv· July 2025

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iSoMAs: Finding isoform expression and somatic mutation associations in human cancers.
Hua Tan, Valer Gotea, Sushil K Jaiswal, Nancy E Seidel, David O Holland

PLoS Comput Biol· March 2025

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The Megacomplex protects ER-alpha from degradation by Fulvestrant in epithelial ovarian cancer.
Sushil Kumar Jaiswal, Kevin Fedkenheuer, Ronak Khamar, Hua Tan, Valer Gotea

Cancer Lett· January 2025

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Characterization and clustering of kinase isoform expression in metastatic melanoma.
David O Holland, Valer Gotea, Kevin Fedkenheuer, Sushil K Jaiswal, Catherine Baugher

PLoS Comput Biol· May 2022

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A novel role for nucleolin in splice site selection.
Kinneret Shefer, Ayub Boulos, Valer Gotea, Maram Arafat, Yair Ben Chaim

RNA Biol· March 2022

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Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer.
Yichao Li, Sushil K Jaiswal, Rupleen Kaur, Dana Alsaadi, Xiaoyu Liang, Valer Gotea

BMC Cancer· July 2021

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Transposable Elements: Classification, Identification, and Their Use As a Tool For Comparative Genomics.
Wojciech Makałowski, Valer Gotea, Amit Pande, Izabela Makałowska

Methods Mol Biol· January 2020

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CAGI experiments: Modeling sequence variant impact on gene splicing using predictions from computational tools.
Valer Gotea, Gennady Margolin, Laura Elnitski

Hum Mutat· September 2019

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Assessing predictions of the impact of variants on splicing in CAGI5.
Stephen M Mount, Žiga Avsec, Liran Carmel, Rita Casadio, Muhammed Hasan Çelik, Valer Gotea

Hum Mutat· September 2019

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Significant associations between driver gene mutations and DNA methylation alterations across many cancer types.
Yun-Ching Chen, Valer Gotea, Gennady Margolin, Laura Elnitski

PLoS Comput Biol· November 2017

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CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Francisco Sánchez-Vega, Valer Gotea, Yun-Ching Chen, Laura Elnitski

World J Gastrointest Oncol· March 2017

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A Case of IL-7R Deficiency Caused by a Novel Synonymous Mutation and Implications for Mutation Screening in SCID Diagnosis.
Fernando Gallego-Bustos, Valer Gotea, José T Ramos-Amador, Rebeca Rodríguez-Pena, Juana Gil-Herrera

Front Immunol· October 2016

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The functional relevance of somatic synonymous mutations in melanoma and other cancers.
Valer Gotea, Jared J Gartner, Nouar Qutob, Laura Elnitski, Yardena Samuels

Pigment Cell Melanoma Res· November 2015

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Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype.
Francisco Sánchez-Vega, Valer Gotea, Gennady Margolin, Laura Elnitski

Epigenetics Chromatin· May 2015

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Ascertaining regions affected by GC-biased gene conversion through weak-to-strong mutational hotspots.
Valer Gotea, Laura Elnitski

Genomics· January 2015

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Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines.
Francisco Sánchez-Vega, Valer Gotea, Hanna M Petrykowska, Gennady Margolin, Thomas C Krivak

Epigenetics· December 2013

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Bidirectional promoters as important drivers for the emergence of species-specific transcripts.
Valer Gotea, Hanna M Petrykowska, Laura Elnitski

PLoS One· September 2013

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Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma.
Jared J Gartner, Stephen C J Parker, Todd D Prickett, Ken Dutton-Regester, Michael L Stitzel, Valer Gotea

Proc Natl Acad Sci U S A· August 2013

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Functional analysis of synonymous substitutions predicted to affect splicing of the CFTR gene.
Alexandra Scott, Hanna M Petrykowska, Timothy Hefferon, Valer Gotea, Laura Elnitski

J Cyst Fibros· December 2012

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Transposable elements and their identification.
Wojciech Makałowski, Amit Pande, Valer Gotea, Izabela Makałowska

Methods Mol Biol· July 2012

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Genome-wide detection of a TFIID localization element from an initial human disease mutation.
Mary Q Yang, Karina Laflamme, Valer Gotea, Clinton H Joiner, Nancy E Seidel

Nucleic Acids Res· March 2011

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Tissue-specific and ubiquitous expression patterns from alternative promoters of human genes.
Edwin Jacox, Valer Gotea, Ivan Ovcharenko, Laura Elnitski

PLoS One· August 2010

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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers.
Valer Gotea, Axel Visel, John M Westlund, Marcelo A Nobrega, Len A Pennacchio

Genome Res· May 2010

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DiRE: identifying distant regulatory elements of co-expressed genes.
Valer Gotea, Ivan Ovcharenko

Nucleic Acids Res· July 2008

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Evolution of genes and genomes on the Drosophila phylogeny.

Nature· November 2007

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