Publications by authors named "Varinderpal Kaur"

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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Varinderpal Kaur

medRxiv· July 2025

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Author Correction: Multi-ancestry polygenic mechanisms of type 2 diabetes.
Kirk Smith, Aaron J Deutsch, Carolyn McGrail, Hyunkyung Kim, Sarah Hsu, Varinderpal Kaur

Nat Med· July 2024

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Initial Insights into the Genetic Variation Associated with Metformin Treatment Failure in Youth with Type 2 Diabetes.
Shylaja Srinivasan, Ling Chen, Miriam Udler, Jennifer Todd, Megan M Kelsey, Varinderpal Kaur

Pediatr Diabetes· April 2024

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Multi-ancestry polygenic mechanisms of type 2 diabetes.
Kirk Smith, Aaron J Deutsch, Carolyn McGrail, Hyunkyung Kim, Sarah Hsu, Varinderpal Kaur

Nat Med· April 2024

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Varinderpal Kaur

Nature· March 2024

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Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.
Kirk Smith, Aaron J Deutsch, Carolyn McGrail, Hyunkyung Kim, Sarah Hsu, Varinderpal Kaur

Res Sq· October 2023

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Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.
Kirk Smith, Aaron J Deutsch, Carolyn McGrail, Hyunkyung Kim, Sarah Hsu, Varinderpal Kaur

medRxiv· September 2023

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The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.
Alicia Huerta-Chagoya, Philip Schroeder, Ravi Mandla, Aaron J Deutsch, Wanying Zhu, Varinderpal Kaur

Diabetologia· July 2023

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Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Josephine H Li, Laura N Brenner, Varinderpal Kaur, Katherine Figueroa, Philip Schroeder

Diabetologia· July 2023

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Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Varinderpal Kaur

medRxiv· March 2023

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Association of GLP1R Polymorphisms With the Incretin Response.
Edgar G Dorsey-Trevino, Varinderpal Kaur, Josep M Mercader, Jose C Florez, Aaron Leong

J Clin Endocrinol Metab· August 2022

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Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19.
Philip H Schroeder, Laura N Brenner, Varinderpal Kaur, Sara J Cromer, Katrina Armstrong

Cardiovasc Diabetol· July 2022

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Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19.
Philip Schroeder, Laura Brenner, Varinderpal Kaur, Sara Cromer, Katrina Armstrong

Res Sq· June 2022

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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Anubha Mahajan, Cassandra N Spracklen, Weihua Zhang, Maggie C Y Ng, Lauren E Petty, Varinderpal Kaur

Nat Genet· May 2022

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Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682.
Adem Y Dawed, Sook Wah Yee, Kaixin Zhou, Nienke van Leeuwen, Yanfei Zhang, Varinderpal Kaur

Diabetes Care· April 2022

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Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.
Mark J O'Connor, Philip Schroeder, Alicia Huerta-Chagoya, Paula Cortés-Sánchez, Silvía Bonàs-Guarch, Varinderpal Kaur

Diabetes· March 2022

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Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas.
Adem Y Dawed, Sook Wah Yee, Kaixin Zhou, Nienke van Leeuwen, Yanfei Zhang, Varinderpal Kaur

Diabetes Care· December 2021

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A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas.
Josephine H Li, Lukasz Szczerbinski, Adem Y Dawed, Varinderpal Kaur, Jennifer N Todd

Diabetes· January 2021

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Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH).
Shylaja Srinivasan, Varinderpal Kaur, Bindu Chamarthi, Katherine R Littleton, Ling Chen

Diabetes Care· March 2018

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The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.
Geoffrey A Walford, Natalia Colomo, Jennifer N Todd, Liana K Billings, Marlene Fernandez, Varinderpal Kaur

PLoS One· March 2016

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Regulation of pancreas duodenum homeobox-1 expression by early growth response-1.
Kazuhiro Eto, Varinderpal Kaur, Melissa K Thomas

J Biol Chem· March 2007

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Regulation of insulin gene transcription by the immediate-early growth response gene Egr-1.
Kazuhiro Eto, Varinderpal Kaur, Melissa K Thomas

Endocrinology· June 2006

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Overexpression of the coactivator bridge-1 results in insulin deficiency and diabetes.
Jamie L Volinic, Jee H Lee, Kazuhiro Eto, Varinderpal Kaur, Melissa K Thomas

Mol Endocrinol· January 2006

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