Publications by authors named "Varughese A Mulamoottil"

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Okra seed polysaccharides mitigate neuroinflammation and cognitive impairment via modulation of Nrf2/HO-1, HMGB1/RAGE/TLR4/NF-κB, NLRP3/Caspase-1, JAK-2/STAT-3, AMPK/SIRT1/m-TOR, PI3K/AKT/CREB/BDNF/TrkB and PERK/CHOP/Bcl-2 axes.
Jilan A Nazeam, Ian Black, Varughese A Mulamoottil, Nabil M Selim, Riham A El Shiekh

Int Immunopharmacol· February 2025

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Synthesis of an Anti-hepatitis B Agent, 2'-Fluoro-6'-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP).
Uma S Singh, Varughese A Mulamoottil, Chung K Chu

J Org Chem· January 2019

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Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and - pyrimidines.
Ji-Seong Yoon, Dnyandev B Jarhad, Gyudong Kim, Akshata Nayak, Long Xuan Zhao, Varughese A Mulamoottil

Eur J Med Chem· July 2018

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2'-Fluoro-6'-methylene carbocyclic adenosine and its phosphoramidate prodrug: A novel anti-HBV agent, active against drug-resistant HBV mutants.
Uma S Singh, Varughese A Mulamoottil, Chung K Chu

Med Res Rev· May 2018

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Asymmetric Synthesis of (-)-6'-β-Fluoro-aristeromycin via Stereoselective Electrophilic Fluorination.
Gyudong Kim, Ji-Seong Yoon, Dnyandev B Jarhad, Young Sup Shin, Mahesh S Majik, Varughese A Mulamoottil

Org Lett· November 2017

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Design, synthesis, and anticancer activity of C8-substituted-4'-thionucleosides as potential HSP90 inhibitors.
Shuhao Qu, Varughese A Mulamoottil, Akshata Nayak, Seungyeon Ryu, Xiyan Hou

Bioorg Med Chem· August 2016

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Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
Girish Chandra, Yang Won Moon, Yoonji Lee, Ji Yong Jang, Jayoung Song, Varughese A Mulamoottil

J Med Chem· June 2015

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