Publications by authors named "Vicky de Winter"

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Autophagy induction by piplartine ameliorates axonal degeneration caused by mutant HSPB1 and HSPB8 in Charcot-Marie-Tooth type 2 neuropathies.
Angela Sisto, Tamira van Wermeskerken, Michael Pancher, Pamela Gatto, Bob Asselbergh, Vicky De Winter

Autophagy· May 2025

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RNA Interference Targeting Small Heat Shock Protein B8 Failed to Improve Distal Hereditary Motor Neuropathy in the Mouse Model.
Leen Vendredy, Vicky De Winter, Jonas Van Lent, Jasmien Orije, Tatiana Da Silva Authier

J Gene Med· February 2025

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Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space.
Elias Adriaenssens, Bob Asselbergh, Pablo Rivera-Mejías, Sven Bervoets, Leen Vendredy, Vicky De Winter

Nat Cell Biol· March 2023

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NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice.
Matthew J Jennings, Alexia Kagiava, Leen Vendredy, Emily L Spaulding, Marina Stavrou, Vicky De Winter

Brain· November 2022

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Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction.
Jonas Van Lent, Peter Verstraelen, Bob Asselbergh, Elias Adriaenssens, Ligia Mateiu, Vicky De Winter

Brain· September 2021

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Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.
Mansour Haidar, Bob Asselbergh, Elias Adriaenssens, Vicky De Winter, Jean-Pierre Timmermans

Autophagy· June 2019

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Sensory neuropathy-causing mutations in ATL3 affect ER-mitochondria contact sites and impair axonal mitochondrial distribution.
Michiel Krols, Bob Asselbergh, Riet De Rycke, Vicky De Winter, Alexandre Seyer

Hum Mol Genet· February 2019

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Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering.
Michiel Krols, Sammy Detry, Bob Asselbergh, Leonardo Almeida-Souza, Anna Kremer, Vicky De Winter

Cell Rep· May 2018

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A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Delphine Bouhy, Manisha Juneja, Istvan Katona, Anne Holmgren, Bob Asselbergh, Vicky De Winter

Acta Neuropathol· January 2018

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Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Thomas Geuens, Vicky De Winter, Nicholas Rajan, Tilmann Achsel, Ligia Mateiu

Acta Neuropathol Commun· January 2017

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Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1.
Simona Capponi, Thomas Geuens, Alessandro Geroldi, Paola Origone, Simonetta Verdiani, Vicky De Winter

Hum Mutat· November 2016

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Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.
Delphine Bouhy, Thomas Geuens, Vicky De Winter, Leonardo Almeida-Souza, Istvan Katona

J Neuromuscul Dis· May 2016

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Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes.
Elke Ydens, Dieter Demon, Guillaume Lornet, Vicky De Winter, Vincent Timmerman

J Neuroinflammation· August 2015

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HSPB1 facilitates the formation of non-centrosomal microtubules.
Leonardo Almeida-Souza, Bob Asselbergh, Vicky De Winter, Sofie Goethals, Vincent Timmerman

PLoS One· March 2014

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Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments.
Anne Holmgren, Delphine Bouhy, Vicky De Winter, Bob Asselbergh, Jean-Pierre Timmermans

Acta Neuropathol· July 2013

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Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance.
Kristien Peeters, Ivan Litvinenko, Bob Asselbergh, Leonardo Almeida-Souza, Teodora Chamova, Vicky De Winter

Am J Hum Genet· June 2013

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Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.
Joy Irobi, Anne Holmgren, Vicky De Winter, Bob Asselbergh, Jan Gettemans

Neuromuscul Disord· August 2012

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Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.
Leonardo Almeida-Souza, Bob Asselbergh, Constantin d'Ydewalle, Kristof Moonens, Sofie Goethals, Vicky de Winter

J Neurosci· October 2011

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Mutant HSPB8 causes motor neuron-specific neurite degeneration.
Joy Irobi, Leonardo Almeida-Souza, Bob Asselbergh, Vicky De Winter, Sofie Goethals

Hum Mol Genet· August 2010

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Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy.
Leonardo Almeida-Souza, Sofie Goethals, Vicky de Winter, Ines Dierick, Rodrigo Gallardo

J Biol Chem· April 2010

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