Publications by authors named "Victoria Head"

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Discovery and Characterization of Zilurgisertib, a Potent and Selective Inhibitor of Activin Receptor-like Kinase‑2 (ALK2) for the Treatment of Fibrodysplasia Ossificans Progressiva.
Thomas Ullrich, Sabine Guth, Luca Arista, Sven Weiler, Nikolaus Stiefl, Victoria Head

ACS Med Chem Lett· November 2025

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Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.
Andreas Weiss, Edwige Lorthiois, Louise Barys, Kim S Beyer, Claudio Bomio-Confaglia, Victoria Head

Cancer Discov· June 2022

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Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva.
Thomas Ullrich, Luca Arista, Sven Weiler, Sylvie Teixeira-Fouchard, Valérie Broennimann, Victoria Head

Bioorg Med Chem Lett· May 2022

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Development of autotaxin inhibitors: A series of tetrazole cinnamides.
Christopher G Thomson, Darren Le Grand, Mark Dowling, David Beattie, Lucy Elphick, Victoria Head

Bioorg Med Chem Lett· January 2021

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Development of autotaxin inhibitors: A series of zinc binding triazoles.
Christopher G Thomson, Darren Le Grand, Mark Dowling, Cara E Brocklehurst, Colin Chinn, Victoria Head

Bioorg Med Chem Lett· July 2018

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Selective inhibition of histamine-evoked Ca signals by compartmentalized cAMP in human bronchial airway smooth muscle cells.
Philippa Dale, Victoria Head, Mark R Dowling, Colin W Taylor

Cell Calcium· May 2018

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Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists.
Lisa Rooney, Agnès Vidal, Anne-Marie D'Souza, Nick Devereux, Brian Masick, Victoria Head

J Med Chem· June 2014

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