Publications by authors named "Victoria Magrioti"

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Synthesis and anti-mycobacterial activity of novel medium-chain β-lactone derivatives: a multi-target strategy to combat .
Thomas Francis, Christina Dedaki, Phoebe Ananida-Dasenaki, Dimitra Bolka, Kanellos Albanis, Victoria Magrioti

RSC Med Chem· July 2025

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Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin.
Dionisios Vourloumis, Ioannis Mavridis, Alexandros Athanasoulis, Ioannis Temponeras, Despoina Koumantou, Victoria Magrioti

J Med Chem· July 2022

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Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives.
Vasiliki Mavrikaki, Alexandros Pagonis, Isabelle Poncin, Ivy Mallick, Stéphane Canaan, Victoria Magrioti

Bioorg Med Chem Lett· May 2022

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α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E (PGE) in Rat Mesangial Cells.
Anastasia Psarra, Maria A Theodoropoulou, Martin Erhardt, Marina Mertiri, Christiana Mantzourani, Victoria Magrioti

Biomolecules· February 2021

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Changes in the cellular fatty acid profile drive the proteasomal degradation of α-synuclein and enhance neuronal survival.
Mary Xylaki, Ioanna Boumpoureka, Maroula G Kokotou, Theodoros Marras, Georgia Papadimitriou, Victoria Magrioti

FASEB J· November 2020

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The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase As to Adrenic Acid Mobilization in Murine Macrophages.
Patricia Monge, Alvaro Garrido, Julio M Rubio, Victoria Magrioti, George Kokotos

Biomolecules· April 2020

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β-Lactones: A Novel Class of Ca-Independent Phospholipase A (Group VIA iPLA) Inhibitors with the Ability To Inhibit β-Cell Apoptosis.
Christina Dedaki, Maroula G Kokotou, Varnavas D Mouchlis, Dimitris Limnios, Xiaoyong Lei, Victoria Magrioti

J Med Chem· March 2019

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Synthesis of Long-Chain β-Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria.
Pierre Santucci, Christina Dedaki, Alexandros Athanasoulis, Laura Gallorini, Anaïs Munoz, Victoria Magrioti

ChemMedChem· February 2019

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2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A.
Maroula G Kokotou, Gerasimia Galiatsatou, Victoria Magrioti, Giorgos Koutoulogenis, Efrosini Barbayianni

Sci Rep· August 2017

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2-Oxoamide inhibitors of cytosolic group IVA phospholipase A2 with reduced lipophilicity.
Georgia Antonopoulou, Victoria Magrioti, Maroula G Kokotou, Aikaterini Nikolaou, Efrosini Barbayianni

Bioorg Med Chem· October 2016

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Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells.
Sofia Vasilakaki, Efrosini Barbayianni, Victoria Magrioti, Oleksandr Pastukhov, Violetta Constantinou-Kokotou

Bioorg Med Chem· July 2016

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Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.
Robert N Bone, Ying Gai, Victoria Magrioti, Maroula G Kokotou, Tomader Ali

Diabetes· February 2015

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Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo.
George Kokotos, Astrid J Feuerherm, Efrosini Barbayianni, Ishita Shah, Mari Sæther, Victoria Magrioti

J Med Chem· September 2014

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Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes.
Tomader Ali, George Kokotos, Victoria Magrioti, Robert N Bone, James A Mobley

PLoS One· April 2014

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Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages.
Luis Gil-de-Gómez, Alma M Astudillo, Carlos Guijas, Victoria Magrioti, George Kokotos

J Immunol· January 2014

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Autotaxin inhibitors: a patent review.
Efrosini Barbayianni, Victoria Magrioti, Panagiota Moutevelis-Minakakis, George Kokotos

Expert Opin Ther Pat· September 2013

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New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2.
Victoria Magrioti, Aikaterini Nikolaou, Annetta Smyrniotou, Ishita Shah, Violetta Constantinou-Kokotou

Bioorg Med Chem· September 2013

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Phospholipase A2 inhibitors for the treatment of inflammatory diseases: a patent review (2010--present).
Victoria Magrioti, George Kokotos

Expert Opin Ther Pat· March 2013

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Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.
Edward A Dennis, Jian Cao, Yuan-Hao Hsu, Victoria Magrioti, George Kokotos

Chem Rev· October 2011

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Inhibition of secreted phospholipases A₂ by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations.
Varnavas D Mouchlis, Victoria Magrioti, Efrosini Barbayianni, Nathan Cermak, Rob C Oslund

Bioorg Med Chem· January 2011

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Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.
George Kokotos, Yuan-Hao Hsu, John E Burke, Constantinos Baskakis, Christoforos G Kokotos, Victoria Magrioti

J Med Chem· May 2010

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Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases.
Victoria Magrioti, George Kokotos

Expert Opin Ther Pat· January 2010

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2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.
Efrosini Barbayianni, Daren Stephens, Andrej Grkovich, Victoria Magrioti, Yuan-Hao Hsu

Bioorg Med Chem· July 2009

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Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis.
Athena Kalyvas, Constantinos Baskakis, Victoria Magrioti, Violetta Constantinou-Kokotou, Daren Stephens

Brain· May 2009

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Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes.
Constantinos Baskakis, Victoria Magrioti, Naomi Cotton, Daren Stephens, Violetta Constantinou-Kokotou

J Med Chem· December 2008

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