Publications by authors named "Vikki Spaulding"

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Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors.
Ben Umiker, Yasmin Hashambhoy-Ramsay, Jeff Smith, Tanzila Rahman, Amy Mueller, Vikki Spaulding

Mol Cancer Ther· April 2023

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Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Jessica D Weaver, Edward C Stack, Joshua A Buggé, Changyun Hu, Lara McGrath, Vikki Spaulding

Oncoimmunology· November 2022

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Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Seungil Han, Robert M Czerwinski, Nicole L Caspers, David C Limburg, WeiDong Ding, Vikki Spaulding

Biochem J· June 2014

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Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with nanomolar potency in a whole-blood assay.
Christoph W Zapf, Brian S Gerstenberger, Li Xing, David C Limburg, David R Anderson, Vikki Spaulding

J Med Chem· November 2012

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Osteogenic effects of a potent Src-over-Abl-selective kinase inhibitor in the mouse.
Richard J Murrills, Shoichi Fukayama, Frank Boschelli, Jeanne J Matteo, Jane Owens, Vikki Spaulding

J Pharmacol Exp Ther· March 2012

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In vitro potency, pharmacokinetic profiles, and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus.
Yulia Vugmeyster, Heath Guay, Pamela Szklut, Ming D Qian, Macy Jin, Vikki Spaulding

MAbs· December 2010

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Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys.
Yulia Vugmeyster, Scott Allen, Pamela Szklut, Andrea Bree, Mark Ryan, Vikki Spaulding

J Transl Med· April 2010

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hKSR-2 inhibits MEKK3-activated MAP kinase and NF-kappaB pathways in inflammation.
Padma L Channavajhala, Vikram R Rao, Vikki Spaulding, Lih-Ling Lin, Y George Zhang

Biochem Biophys Res Commun· September 2005

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Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.
Jing Li, Kathy N Tomkinson, Xiang-Yang Tan, Paul Wu, Grace Yan, Vikki Spaulding

Int Immunopharmacol· May 2004

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Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss.
Vincent Ling, Paul W Wu, Vikki Spaulding, Jan Kieleczawa, Deborah Luxenberg

Genomics· September 2003

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