Publications by authors named "Vikram Shende"

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P450 Electron transfer: Towards in vitro NAD(P)H-independent biocatalysis.
Olivia Paredes, Ava Arabshahi, Jacqueline Hu, Neel Kumar, Vikram Shende

J Inorg Biochem· February 2026

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Isolation of Verrucosins A-E from a Marine sp. Reveals a Unifying Biosynthetic Hypothesis for Linear and Macrocyclic Polyketides.
Darren C Holland, Reiko Iizumi, Vikram V Shende, William Fenical

J Nat Prod· July 2025

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Identification of an Induced Orthosteric Pocket in IL-23: A New Avenue for Non-biological Therapeutic Targeting.
Fabien C Lecomte, Jeremiah S Joseph, Jacek Stalewski, Qingliang Shen, Eric Arnoult, Vikram Shende

ACS Chem Biol· July 2025

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Engineering a Biosynthetic Pathway to Produce (+)-Brevianamides A and B.
Casandra P Sandoval Hurtado, Samantha P Kelly, Vikram Shende, Makayla Perez, Brian J Curtis

ACS Catal· May 2025

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Correction to "Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with ".
Thuan-Ethan Ngo, Andrew Ecker, Byeol Ryu, Aurora Guild, Ariana Remmel, Vikram V Shende

ACS Chem Biol· December 2024

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Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in .
Casandra P Sandoval Hurtado, Samantha P Kelly, Vikram Shende, Makayla Perez, Brian J Curtis

bioRxiv· December 2024

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Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins.
Timothy R Fallon, Vikram V Shende, Igor H Wierzbicki, Amanda L Pendleton, Nathan F Watervoort

Science· August 2024

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The shikimate pathway: gateway to metabolic diversity.
Vikram V Shende, Katherine D Bauman, Bradley S Moore

Nat Prod Rep· April 2024

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Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium JHB Discovered via Coculture with .
Thuan-Ethan Ngo, Andrew Ecker, Byeol Ryu, Aurora Guild, Ariana Remmel, Vikram V Shende

ACS Chem Biol· March 2024

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Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin.
Timothy R Fallon, Vikram V Shende, Igor H Wierzbicki, Robert P Auber, David J Gonzalez

bioRxiv· January 2024

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Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from the Marine Cyanobacterium JHB Discovered via Co-culture with .
Thuan-Ethan Ngo, Andrew Ecker, Aurora Guild, Ariana Remmel, Paul D Boudreau, Vikram V Shende

bioRxiv· July 2023

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Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases.
Vikram V Shende, Natalia R Harris, Jacob N Sanders, Sean A Newmister, Yogan Khatri

Angew Chem Int Ed Engl· May 2023

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Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A.
Samantha P Kelly, Vikram V Shende, Autumn R Flynn, Qingyun Dan, Ying Ye

J Am Chem Soc· October 2022

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Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead.
Katherine D Bauman, Vikram V Shende, Percival Yang-Ting Chen, Daniela B B Trivella, Tobias A M Gulder

Nat Chem Biol· May 2022

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Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase.
Vikram V Shende, Yogan Khatri, Sean A Newmister, Jacob N Sanders, Petra Lindovska

J Am Chem Soc· October 2020

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Fungal-derived brevianamide assembly by a stereoselective semipinacolase.
Ying Ye, Lei Du, Xingwang Zhang, Sean A Newmister, Morgan McCauley, Vikram V Shende

Nat Catal· June 2020

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Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Qingyun Dan, Sean A Newmister, Kimberly R Klas, Amy E Fraley, Timothy J McAfoos, Vikram V Shende

Nat Chem· November 2019

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Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway.
Samuel T Slocum, Andrew N Lowell, Ashootosh Tripathi, Vikram V Shende, Janet L Smith

Methods Enzymol· April 2019

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A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst.
Aaron A Koch, Douglas A Hansen, Vikram V Shende, Lawrence R Furan, K N Houk

J Am Chem Soc· September 2017

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Hepatic HNF1 transcription factors control the induction of PCSK9 mediated by rosuvastatin in normolipidemic hamsters.
Bin Dong, Amar Bahadur Singh, Vikram Ravindra Shende, Jingwen Liu

Int J Mol Med· March 2017

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A novel peroxisome proliferator response element modulates hepatic low-density lipoprotein receptor gene transcription in response to PPARδ activation.
Vikram R Shende, Amar Bahadur Singh, Jingwen Liu

Biochem J· December 2015

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PPARδ activation induces hepatic long-chain acyl-CoA synthetase 4 expression in vivo and in vitro.
Chin Fung Kelvin Kan, Amar Bahadur Singh, Bin Dong, Vikram Ravindra Shende, Jingwen Liu

Biochim Biophys Acta· May 2015

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Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice.
Vikram Ravindra Shende, Minhao Wu, Amar Bahadur Singh, Bin Dong, Chin Fung Kelvin Kan

J Lipid Res· April 2015

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MicroRNAs function as cis- and trans-acting modulators of peripheral circadian clocks.
Vikram R Shende, Sam-Moon Kim, Nichole Neuendorff, David J Earnest

FEBS Lett· August 2014

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A novel posttranscriptional mechanism for dietary cholesterol-mediated suppression of liver LDL receptor expression.
Amar Bahadur Singh, Chin Fung Kelvin Kan, Vikram Shende, Bin Dong, Jingwen Liu

J Lipid Res· July 2014

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