Publications by authors named "Viktor M Pastukh"

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Metabolomic biomarkers predict long-term physical function in survivors of acute respiratory failure.
Adeyeye I Haastrup, Justin T Roberts, Sheetal Gandotra, Emily M Hartsell, Grant T Daly, Viktor M Pastukh

Respir Res· November 2025

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Metabolomic Biomarkers Predict Long-term Physical Function in Survivors of Acute Respiratory Failure.
Adeyeye I Haastrup, Justin T Roberts, Sheetal Gandotra, Emily M Hartsell, Grant T Daly, Viktor M Pastukh

Res Sq· November 2025

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Serum mtDNA DAMP abundance, fragmentation and heteroplasmic variants associate with Acute Respiratory Failure outcome: A secondary analysis of study NCT00976833.
Grant T Daly, Emily M Hartsell, Viktor M Pastukh, Justin T Roberts, Adeyeye I Haastrup

medRxiv· November 2025

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Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury.
Shubham Dubey, Zhihong Yu, Emily Morgan Stephens, Ahmed Lazrak, Israr Ahmad, Viktor M Pastukh

Redox Biol· May 2025

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Mitochondria-Targeted DNA Repair Glycosylase hOGG1 Protects Against HFD-Induced Liver Oxidative Mitochondrial DNA Damage and Insulin Resistance in OGG1-Deficient Mice.
Larysa V Yuzefovych, Hye Lim Noh, Sujin Suk, Anne Michele Schuler, Madhuri S Mulekar, Viktor M Pastukh

Int J Mol Sci· November 2024

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Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury.
Shubham Dubey, Zhihong Yu, Emily Morgan Stephens, Ahmed Lazrak, Israr Ahmad, Viktor M Pastukh

bioRxiv· November 2024

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PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells.
Ji Young Lee, Reece P Stevens, Viktoriya V Pastukh, Viktor M Pastukh, Natalya Kozhukhar

Am J Respir Cell Mol Biol· September 2023

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Effect of Bariatric Surgery on Plasma Cell-Free Mitochondrial DNA, Insulin Sensitivity and Metabolic Changes in Obese Patients.
Larysa V Yuzefovych, Viktor M Pastukh, Madhuri S Mulekar, Kate Ledbetter, William O Richards

Biomedicines· September 2023

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Novel attributes of cell-free plasma mitochondrial DNA in traumatic injury.
Grant T Daly, Viktor M Pastukh, Yong B Tan, C Michael Francis, C Zack Aggen

Clin Transl Med· October 2022

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Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance.
Larysa V Yuzefovych, Viktor M Pastukh, Mykhaylo V Ruchko, Jon D Simmons, William O Richards

PLoS One· March 2020

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Enhanced Mitochondrial DNA Repair Resuscitates Transplantable Lungs Donated After Circulatory Death.
Yong B Tan, Viktor M Pastukh, Olena M Gorodnya, Madhuri S Mulekar, Jon D Simmons

J Surg Res· January 2020

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Plasma Transfusion Products and Contamination with Cellular and Associated Pro-Inflammatory Debris.
Yong B Tan, Richard R Rieske, Jon P Audia, Viktor M Pastukh, Gina C Capley

J Am Coll Surg· September 2019

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Mitochondrial DNA Damage Initiates Acute Lung Injury and Multi-Organ System Failure Evoked in Rats by Intra-Tracheal Pseudomonas Aeruginosa.
Yann-Leei Lee, Boniface Obiako, Olena M Gorodnya, Mykhaylo V Ruchko, Jamie L Kuck, Viktor M Pastukh

Shock· July 2017

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Potential contribution of mitochondrial DNA damage associated molecular patterns in transfusion products to the development of acute respiratory distress syndrome after multiple transfusions.
Jon D Simmons, Yann-Leei L Lee, Viktor M Pastukh, Gina Capley, Cherry A Muscat

J Trauma Acute Care Surg· June 2017

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Mitochondrial DNA damage associated molecular patterns in ventilator-associated pneumonia: Prevention and reversal by intratracheal DNase I.
Jon D Simmons, Daniel R Freno, C Annie Muscat, Boniface Obiako, Yann-Leei L Lee, Viktor M Pastukh

J Trauma Acute Care Surg· January 2017

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Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region.
Viktor M Pastukh, Olena M Gorodnya, Mark N Gillespie, Mykhaylo V Ruchko

Free Radic Biol Med· July 2016

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Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs.
Jamie L Kuck, Boniface O Obiako, Olena M Gorodnya, Viktor M Pastukh, Justin Kua

Am J Physiol Lung Cell Mol Physiol· May 2015

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Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription.
Abu-Bakr Al-Mehdi, Viktor M Pastukh, Brad M Swiger, Darla J Reed, Mita R Patel, Viktoriya V Pastukh

Sci Signal· July 2012

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Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs.
Joshua M Chouteau, Boniface Obiako, Olena M Gorodnya, Viktor M Pastukh, Mykhaylo V Ruchko

Am J Physiol Lung Cell Mol Physiol· December 2011

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Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.
Viktor M Pastukh, Li Zhang, Mykhaylo V Ruchko, Olena Gorodnya, Gina C Bardwell

Int J Chron Obstruct Pulmon Dis· October 2011

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The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells.
Mykhaylo V Ruchko, Olena M Gorodnya, Andres Zuleta, Viktor M Pastukh, Mark N Gillespie

Free Radic Biol Med· May 2011

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Controlled DNA "damage" and repair in hypoxic signaling.
Mark N Gillespie, Viktor M Pastukh, Mykhaylo V Ruchko

Respir Physiol Neurobiol· December 2010

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Hypoxia-induced oxidative base modifications in the VEGF hypoxia-response element are associated with transcriptionally active nucleosomes.
Mykhaylo V Ruchko, Olena M Gorodnya, Viktor M Pastukh, Brad M Swiger, Natavia S Middleton

Free Radic Biol Med· February 2009

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