Publications by authors named "Viktor Posse"

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Small molecules restore mutant mitochondrial DNA polymerase activity.
Sebastian Valenzuela, Xuefeng Zhu, Bertil Macao, Mattias Stamgren, Carol Geukens, Viktor Posse

Nature· June 2025

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Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Xuefeng Zhu, Xie Xie, Hrishikesh Das, Benedict G Tan, Yonghong Shi, Viktor Posse

Cell· June 2022

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Eukaryotic DNA replication with purified budding yeast proteins.
Viktor Posse, Erik Johansson, John F X Diffley

Methods Enzymol· March 2022

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Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression.
Meenakshi Singh, Viktor Posse, Bradley Peter, Maria Falkenberg, Claes M Gustafsson

Nucleic Acids Res· January 2022

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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
Jingkun Zeng, Florian Weissmann, Agustina P Bertolin, Viktor Posse, Berta Canal

Biochem J· July 2021

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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase.
Agustina P Bertolin, Florian Weissmann, Jingkun Zeng, Viktor Posse, Jennifer C Milligan

Biochem J· July 2021

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TEFM regulates both transcription elongation and RNA processing in mitochondria.
Shan Jiang, Camilla Koolmeister, Jelena Misic, Stefan Siira, Inge Kühl, Viktor Posse

EMBO Rep· June 2019

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RNase H1 directs origin-specific initiation of DNA replication in human mitochondria.
Viktor Posse, Ali Al-Behadili, Jay P Uhler, Anders R Clausen, Aurelio Reyes

PLoS Genet· January 2019

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Mutations in mitochondrial DNA causing tubulointerstitial kidney disease.
Thomas M Connor, Simon Hoer, Andrew Mallett, Daniel P Gale, Aurora Gomez-Duran, Viktor Posse

PLoS Genet· March 2017

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Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription.
Viktor Posse, Claes M Gustafsson

J Biol Chem· February 2017

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POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.
Inge Kühl, Maria Miranda, Viktor Posse, Dusanka Milenkovic, Arnaud Mourier

Sci Adv· August 2016

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Mitochondrial transcription termination factor 1 directs polar replication fork pausing.
Yonghong Shi, Viktor Posse, Xuefeng Zhu, Anne K Hyvärinen, Howard T Jacobs

Nucleic Acids Res· July 2016

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Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Christian Kukat, Karen M Davies, Christian A Wurm, Henrik Spåhr, Nina A Bonekamp, Viktor Posse

Proc Natl Acad Sci U S A· September 2015

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TEFM is a potent stimulator of mitochondrial transcription elongation in vitro.
Viktor Posse, Saba Shahzad, Maria Falkenberg, B Martin Hällberg, Claes M Gustafsson

Nucleic Acids Res· March 2015

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The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation.
Viktor Posse, Emily Hoberg, Anke Dierckx, Saba Shahzad, Camilla Koolmeister

Nucleic Acids Res· April 2014

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