Publications by authors named "Vincenzo Summa"

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The role of dopaminergic signalling from physiology to neuroprotection in acute and chronic disorders.
Martina Di Nunzio, Maria Lidia Mignogna, Marco Bacigaluppi, Paola Panina-Bordignon, Paolo Ragonese, Vincenzo Summa

Neurobiol Dis· December 2025

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Selective HDAC6 inhibition by Mesinostat impairs tumor growth and stemness in triple-negative breast cancer.
Ivana Bello, Simona Barone, Anna Guadagni, Camilla Esposito, Morena D'Ariano, Vincenzo Summa

Pharmacol Res· December 2025

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METTL16-mediated inhibition of MXD4 promotes leukemia through activation of the MYC-MAX axis.
Guglielmo Bove, Mehrad Babaei, Alberto Bueno-Costa, Sajid Amin, Nicla Simonelli, Vincenzo Summa

Oncogene· November 2025

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A rapid and robust luciferase-based reporter system to assess SARS-CoV-2 protease activity.
Alessandro Lucini Paioni, Lorena Donnici, Riccardo Nodari, Marika Longo Minnolo, Anastasia Ferraro, Vincenzo Summa

Virology· October 2025

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Challenging triple negative breast cancer through HDAC6 selective inhibition: Novel cap-group identification, structure-activity relationships, computational and biological studies.
Simona Barone, Ivana Bello, Anna Guadagni, Carmen Cerchia, Gessica Filocamo, Vincenzo Summa

Eur J Med Chem· August 2025

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Sustainable Joullié-Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors.
Antonella Ilenia Alfano, Sveva Pelliccia, Simona Barone, Luigi Cutarella, Sacha Michèle Idriss Cancade, Vincenzo Summa

J Med Chem· August 2025

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Fixed combination of palmitoylethanolamide and melatonin in preventive therapy of migraine: results from a randomized clinical trial.
Vincenzo Piccolo, Adua Marzocchi, Maria Maisto, Vincenzo Summa, Gian Carlo Tenore

Front Nutr· April 2025

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Integrating Surface Plasmon Resonance and Docking Analysis for Mechanistic Insights of Tryptase Inhibitors.
Alessia Porta, Candida Manelfi, Carmine Talarico, Andrea Rosario Beccari, Margherita Brindisi, Vincenzo Summa

Molecules· March 2025

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Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.
Maria Kuzikov, Stefano Morasso, Jeanette Reinshagen, Markus Wolf, Vittoria Monaco, Vincenzo Summa

ACS Pharmacol Transl Sci· January 2025

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Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform!
Anna Guadagni, Simona Barone, Antonella Ilenia Alfano, Sveva Pelliccia, Ivana Bello, Vincenzo Summa

Eur J Med Chem· December 2024

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Methyl-Transferase-Like Protein 16 (METTL16): The Intriguing Journey of a Key Epitranscriptomic Player Becoming an Emerging Biological Target.
Simona Barone, Carmen Cerchia, Vincenzo Summa, Margherita Brindisi

J Med Chem· September 2024

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Nutraceutical formulation based on a synergic combination of melatonin and palmitoylethanolamide for the management of allergic events.
Maria Maisto, Vincenzo Piccolo, Adua Marzocchi, Daniela Claudia Maresca, Benedetta Romano, Vincenzo Summa

Front Nutr· August 2024

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A Rapid and Reliable Spectrofluorimetric Method to Measure the Urinary Lactulose/Mannitol Ratio for Dysbiosis Assessment.
Lorenzo Marino Cerrato, Elisabetta Schiano, Fortuna Iannuzzo, Gian Carlo Tenore, Vincenzo Summa

Biomedicines· July 2024

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Optimization and Validation of Procyanidins Extraction and Phytochemical Profiling of Seven Herbal Matrices of Nutraceutical Interest.
Niloufar Keivani, Vincenzo Piccolo, Adua Marzocchi, Maria Maisto, Gian Carlo Tenore, Vincenzo Summa

Antioxidants (Basel)· May 2024

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Effects of Food-Derived Antioxidant Compounds on In Vitro Heavy Metal Intestinal Bioaccessibility.
Maria Maisto, Adua Marzocchi, Roberto Ciampaglia, Vincenzo Piccolo, Niloufar Keivani, Vincenzo Summa

Antioxidants (Basel)· May 2024

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Phytochemical investigation and antioxidant properties of unripe tomato cultivars (Solanum lycopersicum L.).
Vincenzo Piccolo, Maria Maisto, Elisabetta Schiano, Fortuna Iannuzzo, Niloufar Keivani, Vincenzo Summa

Food Chem· April 2024

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Unveiling the modulation of virulence and biofilm formation by selective histone deacetylase 6 inhibitors.
Simona Barone, Baptiste Mateu, Luigia Turco, Sveva Pelliccia, Francesca Lembo, Vincenzo Summa

Front Microbiol· February 2024

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Agri-Food Waste Recycling for Healthy Remedies: Biomedical Potential of Nutraceuticals from Unripe Tomatoes ( L.).
Vincenzo Piccolo, Arianna Pastore, Maria Maisto, Niloufar Keivani, Gian Carlo Tenore, Vincenzo Summa

Foods· January 2024

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Natural Chalcones for the Management of Obesity Disease.
Maria Maisto, Adua Marzocchi, Niloufar Keivani, Vincenzo Piccolo, Vincenzo Summa

Int J Mol Sci· November 2023

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The Urine Metabolome of R6/2 and zQ175DN Huntington's Disease Mouse Models.
Roberto Speziale, Camilla Montesano, Giulia Di Pietro, Daniel Oscar Cicero, Vincenzo Summa

Metabolites· August 2023

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Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses.
Valeria Fumagalli, Pietro Di Lucia, Micol Ravà, Davide Marotta, Elisa Bono, Vincenzo Summa

EMBO Mol Med· May 2023

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Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.
Irina Stefanelli, Angela Corona, Carmen Cerchia, Emilia Cassese, Salvatore Improta, Vincenzo Summa

Eur J Med Chem· May 2023

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Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds.
Antonella Ilenia Alfano, Sveva Pelliccia, Giacomo Rossino, Orazio Chianese, Vincenzo Summa

ACS Med Chem Lett· May 2023

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Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds.
Antonella Ilenia Alfano, Sveva Pelliccia, Giacomo Rossino, Orazio Chianese, Vincenzo Summa

ACS Med Chem Lett· March 2023

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Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation.
Sveva Pelliccia, Antonella Ilenia Alfano, Beatriz Ramos Gomes Da Assunção, Luigia Turco, Francesca Lembo, Vincenzo Summa

Front Chem· March 2023

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