Publications by authors named "Vinod Mootha"

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Delphi-Based Global Consensus on Fuchs Endothelial Corneal Dystrophy. An Endothelial Keratoplasty Learners Group Initiative.
Sanjay V Patel, Nidhi Gupta, Maninder Bhogal, Ula V Jurkunas, Naoki Okumura, V Vinod Mootha

Am J Ophthalmol· December 2025

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Transcriptomic analysis implicates the involvement of RBM20 in Fuchs' endothelial corneal dystrophy with TCF4 repeat expansion.
Xunzhi Zhang, Ze Yu, Aundrea K Westfall, Kunyi Han, V Vinod Mootha

PLoS One· September 2025

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Modulation of TTR gene expression in the eye using modified siRNAs.
Jiaxin Hu, Xin Gong, Jayanta Kundu, Dhrubajyoti Datta, Martin Egli, V Vinod Mootha

Nucleic Acids Res· May 2025

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Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging.
Stanley S J Poh, Kai Yuan Tey, Gary S L Peh, Dawn J H Neo, Hla Myint Htoon, V Vinod Mootha

Ophthalmol Sci· May 2025

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Modulation of Gene Expression in the Eye using Modified Duplex RNAs.
Jiaxin Hu, Xin Gong, Jayanta Kundu, Dhrubajyoti Datta, Martin Egli, V Vinod Mootha

bioRxiv· March 2025

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Increased Risk of Glaucoma in Fuchs Endothelial Corneal Dystrophy Is Independent of TCF4 Trinucleotide Repeat Expansion.
Chao Xing, Sara Schultis, Vladyslav Bondar, Xin Gong, Jess T Whitson, V Vinod Mootha

Cornea· September 2024

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Prevalence of Transcription Factor 4 Gene Triplet Repeat Expansion Associated with Fuchs' Endothelial Corneal Dystrophy in the United States and Global Populations.
Xunzhi Zhang, Ashwani Kumar, Xin Gong, Chao Xing, V Vinod Mootha

Ophthalmol Sci· August 2024

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Modulation of Gene Expression in the Eye with Antisense Oligonucleotides.
Jiaxin Hu, Xin Gong, Yan Fan, Selina Aguilar, Frank Rigo, V Vinod Mootha

Nucleic Acid Ther· December 2023

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Transcriptomic meta-analysis reveals ERRα-mediated oxidative phosphorylation is downregulated in Fuchs' endothelial corneal dystrophy.
Xunzhi Zhang, Ashwani Kumar, Adwait A Sathe, V Vinod Mootha, Chao Xing

PLoS One· December 2023

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Targeting the Expanded /Fuchs' Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates.
Jiaxin Hu, Xiulong Shen, Mahboubeh Kheirabadi, Matthew D Streeter, Ziqing Qian, V Vinod Mootha

ACS Omega· November 2023

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The TCF4 Trinucleotide Repeat Expansion of Fuchs' Endothelial Corneal Dystrophy: Implications for the Anterior Segment of the Eye.
Jiaxin Hu, Xin Gong, Samantha T Johnson, David R Corey, V Vinod Mootha

Invest Ophthalmol Vis Sci· May 2023

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Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.
Brian C Leonard, Sangwan Park, Soohyun Kim, Laura J Young, Iman Jalilian, V Vinod Mootha

Invest Ophthalmol Vis Sci· April 2023

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Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs' Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion.
Matthew Gillings, Andrew Mastro, Xunzhi Zhang, Kelly Kiser, Jane Gu, V Vinod Mootha

Ophthalmol Sci· March 2023

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A novel homozygous missense mutation p.P388S in causes protein instability and retinitis pigmentosa.
DaNae R Woodard, Chao Xing, Pratyusha Ganne, Hanquan Liang, Avinash Mahindrakar, V Vinod Mootha

Mol Vis· November 2021

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Lower Corneal Haze and Aberrations in Descemet Membrane Endothelial Keratoplasty Versus Descemet Stripping Automated Endothelial Keratoplasty in Fellow Eyes for Fuchs Endothelial Corneal Dystrophy.
William H Waldrop, Matthew J Gillings, Danielle M Robertson, W Matthew Petroll, V Vinod Mootha

Cornea· October 2020

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Delivery of Antisense Oligonucleotides to the Cornea.
Viet Q Chau, Jiaxin Hu, Xin Gong, John D Hulleman, Rafael L Ufret-Vincenty, V Vinod Mootha

Nucleic Acid Ther· August 2020

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Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs' Endothelial Corneal Dystrophy.
Ziye Rong, Xin Gong, John D Hulleman, David R Corey, V Vinod Mootha

Transl Vis Sci Technol· August 2020

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Analyzing pre-symptomatic tissue to gain insights into the molecular and mechanistic origins of late-onset degenerative trinucleotide repeat disease.
Yongjun Chu, Jiaxin Hu, Hanquan Liang, Mohammed Kanchwala, Chao Xing, V Vinod Mootha

Nucleic Acids Res· July 2020

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Trinucleotide repeat expansion length as a predictor of the clinical progression of Fuchs' Endothelial Corneal Dystrophy.
Yu Qiang Soh, Gary Peh Swee Lim, Hla Myint Htoon, Xin Gong, V Vinod Mootha

PLoS One· November 2019

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Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy.
Ziye Rong, Jiaxin Hu, David R Corey, V Vinod Mootha

Invest Ophthalmol Vis Sci· September 2019

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Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy.
Jiaxin Hu, Xiulong Shen, Frank Rigo, Thahza P Prakash, V Vinod Mootha

Nucleic Acid Ther· April 2019

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Instability of TCF4 Triplet Repeat Expansion With Parent-Child Transmission in Fuchs' Endothelial Corneal Dystrophy.
Joanna S Saade, Chao Xing, Xin Gong, Zhengyang Zhou, V Vinod Mootha

Invest Ophthalmol Vis Sci· August 2018

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Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs' dystrophy.
Jiaxin Hu, Ziye Rong, Xin Gong, Zhengyang Zhou, Vivek K Sharma, V Vinod Mootha

Hum Mol Genet· March 2018

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Supervised resident manual small-incision cataract surgery outcomes at large urban United States residency training program.
Ross Lynds, Brock Hansen, Preston H Blomquist, V Vinod Mootha

J Cataract Refract Surg· January 2018

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Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy.
V Vinod Mootha, Brock Hansen, Ziye Rong, Pradeep P Mammen, Zhengyang Zhou

Invest Ophthalmol Vis Sci· September 2017

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