Publications by authors named "Viola Melone"

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BRPF1 in cancer epigenetics: a key regulator of histone acetylation and a promising therapeutic target.
Elena Alexandrova, Roberto Parisi, Marharyta Smal, Domenico Di Rosa, Alfonso Carleo, Viola Melone

Cell Death Discov· October 2025

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Multi-omics based and AI-driven drug repositioning for epigenetic therapy in female malignancies.
Annamaria Salvati, Viola Melone, Alessandro Giordano, Jessica Lamberti, Domenico Palumbo

J Transl Med· July 2025

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LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer.
Viola Melone, Domenico Palumbo, Luigi Palo, Noemi Brusco, Annamaria Salvati

Cell Death Dis· February 2025

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Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers.
Annamaria Salvati, Giorgio Giurato, Jessica Lamberti, Ilaria Terenzi, Laura Crescenzo, Viola Melone

Mol Cancer· August 2024

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Functional Relationships between Long Non-Coding RNAs and Estrogen Receptor Alpha: A New Frontier in Hormone-Responsive Breast Cancer Management.
Viola Melone, Annamaria Salvati, Noemi Brusco, Elena Alexandrova, Ylenia D'Agostino

Int J Mol Sci· January 2023

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Combinatorial targeting of menin and the histone methyltransferase DOT1L as a novel therapeutic strategy for treatment of chemotherapy-resistant ovarian cancer.
Elena Alexandrova, Jessica Lamberti, Domenico Memoli, Claudia Quercia, Viola Melone

Cancer Cell Int· November 2022

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Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis.
Viola Melone, Annamaria Salvati, Domenico Palumbo, Giorgio Giurato, Giovanni Nassa

J Transl Med· July 2022

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Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo

Breast Cancer Res· July 2022

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Nasopharyngeal virome analysis of COVID-19 patients during three different waves in Campania region of Italy.
Carlo Ferravante, Giuseppina Sanna, Viola Melone, Aurore Fromentier, Teresa Rocco

J Med Virol· May 2022

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Histone Methyltransferase DOT1L as a Promising Epigenetic Target for Treatment of Solid Tumors.
Elena Alexandrova, Annamaria Salvati, Giovanni Pecoraro, Jessica Lamberti, Viola Melone

Front Genet· April 2022

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An Overview of Candidate Therapeutic Target Genes in Ovarian Cancer.
Elena Alexandrova, Giovanni Pecoraro, Assunta Sellitto, Viola Melone, Carlo Ferravante

Cancers (Basel)· June 2020

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