Publications by authors named "Virgil Percec"

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Extraordinary Tolerance of the Cogwheel Mechanism of Helical Self-Organization to Structural Defects.
Dipankar Sahoo, Devendra S Maurya, Jasper Adamson, Benjamin E Partridge, Mihai Peterca, Virgil Percec

J Am Chem Soc· December 2025

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Harnessing the Electron-Withdrawing Inductive Effect of One-Component Ionizable Amphiphilic Janus Dendrimers Unveils Cation-π Interactions and Their Important Roles to Targeted mRNA Delivery.
Mahwish Arshad, Elena N Atochina-Vasserman, Devendra S Maurya, Juncheng Lu, Nathan Ona, Virgil Percec

J Am Chem Soc· June 2025

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Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers.
Jaclynn A Meshanni, Emily R Stevenson, Dapeng Zhang, Rachel Sun, Nathan A Ona, Virgil Percec

Nat Commun· February 2025

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Toward a Complete Elucidation of the Primary Structure-Activity in Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers for In Vivo Delivery of Luc-mRNA.
Dipankar Sahoo, Elena N Atochina-Vasserman, Juncheng Lu, Devendra S Maurya, Nathan Ona, Virgil Percec

Biomacromolecules· January 2025

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Porous helical supramolecular columns self-organized the fluorophobic effect of a semifluorinated tapered dendron.
Dipankar Sahoo, Mihai Peterca, Mohammad R Imam, Devendra S Maurya, Virgil Percec

J Mater Chem B· December 2024

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Unwinding Spherical Helices Increases Entropy and Stability of Frank-Kasper and Body-Centered-Cubic Periodic Arrays To Facilitate Discrimination between Self-Organization Mechanisms.
Dipankar Sahoo, Mihai Peterca, Virgil Percec

J Am Chem Soc· November 2024

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Hierarchical Self-Organization and Disorganization of Helical Supramolecular Columns Mediated by H-Bonding and Shape Complementarity.
Dipankar Sahoo, Mihai Peterca, Virgil Percec

J Am Chem Soc· October 2024

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Accelerated Ten-Gram-Scale Synthesis of One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer 97.
Mahwish Arshad, Elena N Atochina-Vasserman, Srijay S Chenna, Devendra S Maurya, Muhammad Irhash Shalihin, Virgil Percec

Biomacromolecules· October 2024

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Designing Highly Ordered Helical and Nonhelical Porous Crystalline and Disordered Nonhelical Columnar Liquid Crystalline Self-Organizations.
Dipankar Sahoo, Mihai Peterca, Virgil Percec

J Am Chem Soc· August 2024

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Cogwheel Mechanism of Helical Self-Organization is Thermodynamically Controlled, Self-Repairing, and Universal.
Dipankar Sahoo, Mihai Peterca, Pawaret Leowanawat, Virgil Percec

J Am Chem Soc· July 2024

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Targeted delivery of TGF-β mRNA to lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers.
Elena Atochina-Vasserman, Jaclynn Meshanni, Emily Stevenson, Dapeng Zhang, Rachel Sun, Virgil Percec

Res Sq· July 2024

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From Frank-Kasper, Quasicrystals, and Biological Membrane Mimics to Reprogramming the Living Factory to Target the Delivery of mRNA with One-Component Amphiphilic Janus Dendrimers.
Virgil Percec, Dipankar Sahoo

Biomacromolecules· March 2024

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Aptamer-Targeted Dendrimersomes Assembled from Azido-Modified Janus Dendrimers "Clicked" to DNA.
Paige Bristow, Kyle Schantz, Zoe Moosbrugger, Kailey Martin, Haley Liebenberg, Virgil Percec

Biomacromolecules· March 2024

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The Constitutional Isomerism of One-Component Ionizable Amphiphilic Janus Dendrimers Orchestrates the Total and Targeted Activities of mRNA Delivery.
Dipankar Sahoo, Elena N Atochina-Vasserman, Devendra S Maurya, Mahwish Arshad, Srijay S Chenna, Virgil Percec

J Am Chem Soc· February 2024

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Glycan-Driven Formation of Raft-Like Domains with Hierarchical Periodic Nanoarrays on Dendrimersome Synthetic Cells.
Anna M Wagner, Nina Yu Kostina, Qi Xiao, Michael L Klein, Virgil Percec

Biomacromolecules· January 2024

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Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers.
Juncheng Lu, Elena N Atochina-Vasserman, Devendra S Maurya, Dipankar Sahoo, Nathan Ona, Virgil Percec

J Am Chem Soc· August 2023

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Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids.
Juncheng Lu, Elena N Atochina-Vasserman, Devendra S Maurya, Muhammad Irhash Shalihin, Dapeng Zhang, Virgil Percec

Pharmaceutics· May 2023

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Stimuli-Responsive Principles of Supramolecular Organizations Emerging from Self-Assembling and Self-Organizable Dendrons, Dendrimers, and Dendronized Polymers.
Virgil Percec, Dipankar Sahoo, Jasper Adamson

Polymers (Basel)· April 2023

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Self-Assembly of Glycerol-Amphiphilic Janus Dendrimers Amplifies and Indicates Principles for the Selection of Stereochemistry by Biological Membranes.
Dapeng Zhang, Qi Xiao, Mehrnoush Rahimzadeh, Matthew Liu, Cesar Rodriguez-Emmenegger, Virgil Percec

J Am Chem Soc· February 2023

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Assembling Complex Macromolecules and Self-Organizations of Biological Relevance with Cu(I)-Catalyzed Azide-Alkyne, Thio-Bromo, and TERMINI Double "Click" Reactions.
Adrian Moreno, Gerard Lligadas, Jasper Adamson, Devendra S Maurya, Virgil Percec

Polymers (Basel)· February 2023

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Zwitterionic Dendrimersomes: A Closer Xenobiotic Mimic of Cell Membranes.
Anton Joseph, Anna M Wagner, Manuela Garay-Sarmiento, Mina Aleksanyan, Tamás Haraszti, Virgil Percec

Adv Mater· December 2022

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The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity.
Dapeng Zhang, Elena N Atochina-Vasserman, Juncheng Lu, Devendra S Maurya, Qi Xiao, Virgil Percec

J Am Chem Soc· March 2022

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Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers.
Dapeng Zhang, Elena N Atochina-Vasserman, Devendra S Maurya, Matthew Liu, Qi Xiao, Virgil Percec

J Am Chem Soc· November 2021

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An Accelerated Modular-Orthogonal Ni-Catalyzed Methodology to Symmetric and Nonsymmetric Constitutional Isomeric AB to AB Dendrons Exhibiting Unprecedented Self-Organizing Principles.
Virgil Percec, Shitao Wang, Ning Huang, Benjamin E Partridge, Xuefeng Wang

J Am Chem Soc· October 2021

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One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA.
Dapeng Zhang, Elena N Atochina-Vasserman, Devendra S Maurya, Ning Huang, Qi Xiao, Virgil Percec

J Am Chem Soc· August 2021

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