Publications by authors named "Virginia Pulito"

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A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions.
Marc Damelin, Alexander Bankovich, Jeffrey Bernstein, Justin Lucas, Liang Chen, Virginia Pulito

Sci Transl Med· January 2017

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Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions.
Marc Damelin, Alexander Bankovich, Albert Park, Jorge Aguilar, Wade Anderson, Virginia Pulito

Clin Cancer Res· September 2015

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Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.
Michele P Kelly, Sheree F Logue, Julie Brennan, Jonathon P Day, Subha Lakkaraju, Virginia L Pulito

Proc Natl Acad Sci U S A· May 2010

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The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders?
Sheree F Logue, Steven M Grauer, Janet Paulsen, Radka Graf, Noel Taylor, Virginia L Pulito

Mol Cell Neurosci· December 2009

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Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.
Steven M Grauer, Virginia L Pulito, Rachel L Navarra, Michele P Kelly, Cody Kelley

J Pharmacol Exp Ther· November 2009

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Synthesis, in vitro activities of (2-cyclopropoxyphenyl)piperidine derivatives for alpha 1a and alpha 1d adrenergic receptor inhibitors.
Shengjian Li, George Chiu, Virginia L Pulito, Jingchun Liu, Peter J Connolly

Med Chem· January 2009

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Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory.
Feng Liu, Mark Day, Luis C Muñiz, Daniel Bitran, Robert Arias, Virginia Pulito

Nat Neurosci· March 2008

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(Phenylpiperazinyl)cyclohexylureas: discovery of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
George Chiu, Shengjian Li, Peter J Connolly, Virginia Pulito, Jingchun Liu

Bioorg Med Chem Lett· January 2008

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Aminocyclohexylsulfonamides: discovery of metabolically stable alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
George Chiu, Shengjian Li, Hong Cai, Peter J Connolly, Sean Peng, Virginia Pulito

Bioorg Med Chem Lett· November 2007

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(Phenylpiperidinyl)cyclohexylsulfonamides: development of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
George Chiu, Shengjian Li, Peter J Connolly, Virginia Pulito, Jingchun Liu

Bioorg Med Chem Lett· July 2007

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(Arylpiperazinyl)cyclohexylsufonamides: discovery of alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS).
George Chiu, Shengjian Li, Peter J Connolly, Virginia Pulito, Jingchun Liu

Bioorg Med Chem Lett· June 2007

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1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands.
Shengjian Li, George Chiu, Virginia L Pulito, Jingchun Liu, Peter J Connolly

Bioorg Med Chem Lett· March 2007

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Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists.
Haripada Khatuya, Richard H Hutchings, Gee-Hong Kuo, Virginia L Pulito, Linda K Jolliffe

Bioorg Med Chem Lett· September 2002

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Novel thiophene derivatives for the treatment of benign prostatic hyperplasia.
Haripada Khatuya, Virginia L Pulito, Linda K Jolliffe, Xiaobing Li, William V Murray

Bioorg Med Chem Lett· August 2002

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