Publications by authors named "Virpi Launonen"

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Presence of Stromal Cells Enhances Epithelial-to-Mesenchymal Transition (EMT) Induction in Lung Bronchial Epithelium after Protracted Exposure to Oxidative Stress of Gamma Radiation.
Anna Acheva, Siamak Haghdoost, Alice Sollazzo, Virpi Launonen, Meerit Kämäräinen

Oxid Med Cell Longev· March 2020

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Assessment of targeted and non-targeted responses in cells deficient in ATM function following exposure to low and high dose X-rays.
Anne Kiuru, Meerit Kämäräinen, Sirpa Heinävaara, Katri Pylkäs, Kim Chapman, Virpi Launonen

PLoS One· June 2015

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A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
Carmel Mothersill, Francesca Antonelli, Jostein Dahle, Valentina Dini, Hargita Hegyesi, Virpi Launonen

Int J Radiat Biol· October 2012

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Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer.
Silva Saarinen, Pia Vahteristo, Rainer Lehtonen, Kristiina Aittomäki, Virpi Launonen

Fam Cancer· September 2012

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MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
Netta Mäkinen, Miika Mehine, Jaana Tolvanen, Eevi Kaasinen, Yilong Li, Virpi Launonen

Science· October 2011

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Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
Chiara Bardella, Mona El-Bahrawy, Norma Frizzell, Julie Adam, Nicola Ternette, Virpi Launonen

J Pathol· September 2011

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Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma.
Silva Saarinen, Pia Vahteristo, Virpi Launonen, Kaarle Franssila, Sirpa Kivirikko

Br J Haematol· August 2011

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Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma.
Silva Saarinen, Mervi Aavikko, Kristiina Aittomäki, Virpi Launonen, Rainer Lehtonen

Blood· July 2011

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Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.
Houman Ashrafian, Linda O'Flaherty, Julie Adam, Violetta Steeples, Yuen-Li Chung, Virpi Launonen

Cancer Res· November 2010

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Mutations in the circadian gene CLOCK in colorectal cancer.
Pia Alhopuro, Mikael Björklund, Heli Sammalkorpi, Mikko Turunen, Sari Tuupanen, Virpi Launonen

Mol Cancer Res· July 2010

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No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome.
Pia Vahteristo, Taru A Koski, Laura Näätsaari, Maija Kiuru, Auli Karhu, Virpi Launonen

Fam Cancer· June 2010

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The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas.
Elina Heliövaara, Anniina Raitila, Virpi Launonen, Anders Paetau, Johanna Arola

Am J Pathol· December 2009

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Array comparative genomic hybridization identifies a distinct DNA copy number profile in renal cell cancer associated with hereditary leiomyomatosis and renal cell cancer.
Taru A Koski, Heli J Lehtonen, Kowan J Jee, Shinsuke Ninomiya, Simon A Joosse, Virpi Launonen

Genes Chromosomes Cancer· July 2009

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Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer.
Taru Ahvenainen, Heli J Lehtonen, Rainer Lehtonen, Pia Vahteristo, Kristiina Aittomäki, Virpi Launonen

Cancer Genet Cytogenet· June 2008

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Unregulated smooth-muscle myosin in human intestinal neoplasia.
Pia Alhopuro, Denis Phichith, Sari Tuupanen, Heli Sammalkorpi, Miranda Nybondas, Virpi Launonen

Proc Natl Acad Sci U S A· April 2008

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Stress-induced expression of a novel variant of human fumarate hydratase (FH).
Heli J Lehtonen, Sanna K Ylisaukko-Oja, Maija Kiuru, Auli Karhu, Rainer Lehtonen, Virpi Launonen

Gene Expr· March 2008

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The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency.
Jean-Pierre Bayley, Virpi Launonen, Ian P M Tomlinson

BMC Med Genet· March 2008

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Increased HIF1 alpha in SDH and FH deficient tumors does not cause microsatellite instability.
Heli J Lehtonen, Markus J Mäkinen, Maija Kiuru, Päivi Laiho, Riitta Herva, Virpi Launonen

Int J Cancer· September 2007

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Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.
Marianthi Georgitsi, Anniina Raitila, Auli Karhu, Rob B van der Luijt, Cora M Aalfs, Virpi Launonen

J Clin Endocrinol Metab· August 2007

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Conventional renal cancer in a patient with fumarate hydratase mutation.
Heli J Lehtonen, Ignacio Blanco, Jose M Piulats, Riitta Herva, Virpi Launonen

Hum Pathol· May 2007

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Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations.
Marianthi Georgitsi, Anniina Raitila, Auli Karhu, Karoliina Tuppurainen, Markus J Mäkinen, Virpi Launonen

Proc Natl Acad Sci U S A· March 2007

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Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients.
Sanna K Ylisaukko-oja, Maija Kiuru, Heli J Lehtonen, Rainer Lehtonen, Eero Pukkala, Virpi Launonen

Int J Cancer· July 2006

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Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma.
Sanna K Ylisaukko-oja, Cezary Cybulski, Rainer Lehtonen, Maija Kiuru, Joanna Matyjasik, Virpi Launonen

Eur J Hum Genet· July 2006

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Pituitary adenoma predisposition caused by germline mutations in the AIP gene.
Outi Vierimaa, Marianthi Georgitsi, Rainer Lehtonen, Pia Vahteristo, Antti Kokko, Virpi Launonen

Science· May 2006

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Mutations in the human LKB1/STK11 gene.
Virpi Launonen

Hum Mutat· October 2005

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