Publications by authors named "Vladimir Subr"

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Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach.
Jana Pokorná, Martin Hadzima, Alena Křenková, Joshua D Smith, Vladimír Šubr

Sci Rep· November 2025

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Polymer Nanomedicines with pH-Triggered Pirarubicin Release: Revealing the Role of Carrier Hydrophilicity and Release Kinetics in Anticancer Performance.
Sára Pytlíková, Benchun Jiang, Lucie Woldřichová, Kevin Kotalík, Ladislav Androvič

Biomacromolecules· October 2025

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Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases.
Martin Hadzima, Franco F Faucher, Kristýna Blažková, Joshua J Yim, Matteo Guerra

ACS Sens· July 2024

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Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
Mohammad Reza Zamani, Martin Hadzima, Kristýna Blažková, Vladimír Šubr, Tereza Ormsby

J Biol Chem· June 2024

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Polymer-tethered quenched fluorescent probes for enhanced imaging of tumor associated proteases.
Martin Hadzima, Franco Faucher, Kristýna Blažková, Joshua J Yim, Matteo Guerra

bioRxiv· May 2024

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Highly Effective Synthetic Polymer-Based Blockers of Non-Specific Interactions in Immunochemical Analyses.
Vladimír Šubr, Libor Kostka, Jan Plicka, Ondřej Sedláček, Tomáš Etrych

Polymers (Basel)· March 2024

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Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid).
Michal Pechar, Vlastimil Král, Lucie Kracíková, Ladislav Androvič, Eliška Hrdá

Int J Pharm· December 2023

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Polymer theranostics with multiple stimuli-based activation of photodynamic therapy and tumor imaging.
Marina Rodrigues Tavares, Rayhanul Islam, Vladimír Šubr, Steffen Hackbarth, Shanghui Gao

Theranostics· October 2023

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Singlet Oxygen : It Is All about Intensity-Part 2.
Steffen Hackbarth, Shanghui Gao, Vladimír Šubr, Lisheng Lin, Jakob Pohl

J Pers Med· April 2023

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HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties.
Rayhanul Islam, Kevin Kotalík, Vladimír Šubr, Shanghui Gao, Jian-Rong Zhou

Nanomedicine· February 2023

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Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.
Jana Kousalová, Milada Šírová, Libor Kostka, Vladimír Šubr, Jiřina Kovářová

Nanomedicine· August 2022

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Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.
Libor Kostka, Ladislav Sivák, Vladimír Šubr, Jiřina Kovářová, Milada Šírová

Biomacromolecules· June 2022

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Singlet Oxygen In Vivo: It Is All about Intensity.
Steffen Hackbarth, Rayhanul Islam, Vladimír Šubr, Tomáš Etrych, Jun Fang

J Pers Med· May 2022

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Tumor Stimulus-Responsive Biodegradable Diblock Copolymer Conjugates as Efficient Anti-Cancer Nanomedicines.
Vladimír Šubr, Robert Pola, Shanghui Gao, Rayhanul Islam, Takuma Hirata

J Pers Med· April 2022

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The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody).
Kristyna Blažková, Jana Beranová, Martin Hradilek, Libor Kostka, Vladimír Šubr

J Biol Chem· November 2021

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Unraveling the role of Intralipid in suppressing off-target delivery and augmenting the therapeutic effects of anticancer nanomedicines.
Rayhanul Islam, Shanghui Gao, Waliul Islam, Vladimír Šubr, Jian-Rong Zhou

Acta Biomater· May 2021

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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Ladislav Sivák, Vladimír Šubr, Jiřina Kovářová, Barbora Dvořáková, Milada Šírová

J Control Release· April 2021

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HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours.
Libor Kostka, Lenka Kotrchová, Vladimír Šubr, Alena Libánská, Carolina A Ferreira

Biomaterials· March 2020

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Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon

PLoS Biol· October 2019

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Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents.
Jun Fang, Rayhanul Islam, Waliul Islam, Hongzhuan Yin, Vladimir Subr

Pharmaceutics· July 2019

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Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors.
Steffen Hackbarth, Waliul Islam, Jun Fang, Vladimír Šubr, Beate Röder

Photochem Photobiol Sci· June 2019

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Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines.
Waliul Islam, Jun Fang, Takahisa Imamura, Tomas Etrych, Vladimir Subr

Mol Cancer Ther· December 2018

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Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes.
Petr Šimon, Tomáš Knedlík, Kristýna Blažková, Petra Dvořáková, Anna Březinová

ACS Chem Biol· December 2018

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N-(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production.
Eva Koziolová, Libor Kostka, Lenka Kotrchová, Vladimír Šubr, Rafal Konefal

Biomacromolecules· October 2018

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N-(2-hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide-a, a promising tumor-targeted theranostic probe for photodynamic therapy and imaging.
Jun Fang, Vladimír Šubr, Waliul Islam, Steffen Hackbarth, Rayhanul Islam

Eur J Pharm Biopharm· September 2018

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