Publications by authors named "Vladimir V Shuvaev"

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Targeting DNA-LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity.
Nicolas Marzolini, Taylor V Brysgel, Ryan J Rahman, Eno-Obong Essien, Saw Y Nwe, Vladimir V Shuvaev

bioRxiv· October 2025

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Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications.
Máté Vadovics, Wenchen Zhao, Emily F Daley, Kieu Lam, Owen Daly, Vladimir V Shuvaev

Nat Nanotechnol· September 2025

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Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo.
Vladimir V Shuvaev, Ying K Tam, Benjamin W Lee, Jacob W Myerson, Alan Herbst, Tea I Shuvaeva

Proc Natl Acad Sci U S A· July 2025

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Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system.
Hamideh Parhiz, Vladimir V Shuvaev, Qin Li, Tyler E Papp, Awurama A Akyianu

Mol Ther Nucleic Acids· June 2024

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Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Vladimir V Shuvaev, Sahily Reyes-Esteves, Helene C Descamps, Tea Shuvaeva

Mol Ther· May 2024

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Engineered Dual Antioxidant Enzyme Complexes Targeting ICAM-1 on Brain Endothelium Reduce Brain Injury-Associated Neuroinflammation.
Brian M Leonard, Vladimir V Shuvaev, Trent A Bullock, Kalpani N Udeni Galpayage Dona, Vladimir R Muzykantov

Bioengineering (Basel)· February 2024

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Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Sahily Reyes-Esteves, Helene C Descamps, Vladimir V Shuvaev, Tea Shuvaeva

bioRxiv· June 2023

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Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding.
Carla Riera-Domingo, Eduarda Leite-Gomes, Iris Charatsidou, Peihua Zhao, Giovanna Carrá, Vladimir V Shuvaev

Sci Adv· March 2023

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Mechanisms by Which Liposomes Improve Inhaled Drug Delivery for Alveolar Diseases.
Laura T Ferguson, Xiaonan Ma, Jacob W Myerson, Jichuan Wu, Patrick M Glassman, Vladimir V Shuvaev

Adv Nanobiomed Res· March 2023

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Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
Hamideh Parhiz, Jacob S Brenner, Priyal N Patel, Tyler E Papp, Hamna Shahnawaz, Vladimir V Shuvaev

J Control Release· April 2022

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Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers.
Laura T Ferguson, Elizabeth D Hood, Tea Shuvaeva, Vladimir V Shuvaev, Maria C Basil

ACS Nano· March 2022

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Targeting drug delivery in the vascular system: Focus on endothelium.
Patrick M Glassman, Jacob W Myerson, Laura T Ferguson, Raisa Y Kiseleva, Vladimir V Shuvaev

Adv Drug Deliv Rev· August 2021

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Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605).
Ralph A Pietrofesa, Kyewon Park, Om P Mishra, Darrah Johnson-McDaniel, Jacob W Myerson, Vladimir V Shuvaev

Int J Mol Sci· August 2021

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Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.
Oscar A Marcos-Contreras, Colin F Greineder, Raisa Yu Kiseleva, Hamideh Parhiz, Landis R Walsh, Vladimir V Shuvaev

Proc Natl Acad Sci U S A· February 2020

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Cross-linker-Modulated Nanogel Flexibility Correlates with Tunable Targeting to a Sterically Impeded Endothelial Marker.
Jacob Wheatley Myerson, Olivia McPherson, Kelsey G DeFrates, Jenna H Towslee, Oscar A Marcos-Contreras, Vladimir V Shuvaev

ACS Nano· October 2019

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Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury.
Evan M Lutton, S Katie Farney, Allison M Andrews, Vladimir V Shuvaev, Gwo-Yu Chuang

Front Neurol· June 2019

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Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae.
Vladimir V Shuvaev, Makan Khoshnejad, Katherine W Pulsipher, Raisa Yu Kiseleva, Evguenia Arguiri

Biomaterials· December 2018

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PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
Hamideh Parhiz, Vladimir V Shuvaev, Norbert Pardi, Makan Khoshnejad, Raisa Yu Kiseleva

J Control Release· December 2018

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Targeting therapeutics to endothelium: are we there yet?
Raisa Yu Kiseleva, Patrick M Glassman, Colin F Greineder, Elizabeth D Hood, Vladimir V Shuvaev

Drug Deliv Transl Res· August 2018

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Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles.
Jacob W Myerson, Bruce Braender, Olivia Mcpherson, Patrick M Glassman, Raisa Y Kiseleva, Vladimir V Shuvaev

Adv Mater· August 2018

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Ferritin-based drug delivery systems: Hybrid nanocarriers for vascular immunotargeting.
Makan Khoshnejad, Hamideh Parhiz, Vladimir V Shuvaev, Ivan J Dmochowski, Vladimir R Muzykantov

J Control Release· July 2018

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Targeting superoxide dismutase to endothelial caveolae profoundly alleviates inflammation caused by endotoxin.
Vladimir V Shuvaev, Raisa Yu Kiseleva, Evguenia Arguiri, Carlos H Villa, Silvia Muro

J Control Release· February 2018

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The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series).
Jacob S Brenner, Raisa Yu Kiseleva, Patrick M Glassman, Hamideh Parhiz, Colin F Greineder, Vladimir V Shuvaev

Pulm Circ· December 2017

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Superoxide Dismutase-Loaded Porous Polymersomes as Highly Efficient Antioxidants for Treating Neuropathic Pain.
Sonia Kartha, Lesan Yan, Christine L Weisshaar, Meagan E Ita, Vladimir V Shuvaev

Adv Healthc Mater· September 2017

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Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.
Luca Goitre, Peter V DiStefano, Andrea Moglia, Nicholas Nobiletti, Eva Baldini, Vladimir V Shuvaev

Sci Rep· August 2017

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